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Exam (elaborations)

NU643 WEEK 4 QUESTIONS WITH CORRECT ANSWERS 2025

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NU643 WEEK 4 QUESTIONS WITH CORRECT ANSWERS 2025

Institution
NU643/ NU 643
Course
NU643/ NU 643








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Written for

Institution
NU643/ NU 643
Course
NU643/ NU 643

Document information

Uploaded on
March 10, 2025
Number of pages
4
Written in
2024/2025
Type
Exam (elaborations)
Contains
Questions & answers

Subjects

  • nu643 week 4 questions with correct answers 2025

Content preview

NU643 WEEK 4 QUESTIONS WITH
CORRECT ANSWERS 2025
TheoriesQofQschizophrenia.Q-QcorrectQanswerQ-
elevationsQofQdopamine,QepigeneticsQ(genesQbeingQturnedQonQandQoffQdueQtoQenvironment),Qenmda/Qglut
amateQdefectiveQgenesQinherited-QenvironmentalQpressuresQturnQonQdefectiveQgenes



MesocorticalQdopamineQpathwayQ-QcorrectQanswerQ-
negQsymptoms:Q5QasQalogia,Qavolition,Qasociality,Qanhendonia,QaffectiveQblunting,QvtaQtoQprefrontalQcortex
:QcognitiveQchanges,QslowingQofQthoughtQ(lowQlevelsQofQdopamineQinQmesocorticalQpathway),QdrugsQtarge
tQthisQareaQtoQincQdopamineQ(becauseQthereQisQlessQdopamine)



TuberoinfundibularQdopamineQpathwayQ-QcorrectQanswerQ-
incQprolactin,QdueQtoQtheQhypothamus,QblocksQdopamine,QwhichQinQturnQincreasesQprolactinQ(inverseQrela
tionshipQwithQdopamineQ(amenorrhea,QgalactorrheaQ(milkQinQbreast)-risperidone



NigrostriatalQdopamineQpathwayQ-QcorrectQanswerQ-
movementQdisorders:QtardiveQdyskinesia,QextrapyramidalQsymptoms,Qparkinsons's,QslowQbrady-
dyskinesia,Qtremors



MesolimbicQdopamineQpathwayQ-QcorrectQanswerQ-
positiveQsymptoms:Q(hallucinations,QrapidQspeech,Qdelusions)QhyperactivityQinQthisQpathway.QTheQmesoli
mbicQpathway,QsometimesQreferredQtoQasQtheQrewardQpathway,QisQaQdopaminergicQpathwayQinQtheQbrain.



Conventional/typicalQantipsychoticsQ-QcorrectQanswerQ-
haloperidolQandQchlorpromazineQ(1stQgeneration)QtendQtoQblockQdopamineQd2QreceptorsQinQallQofQtheQdo
paminergicQpathwaysQofQtheQbrain.



AtypicalQ2ndQgenerationsQ-QcorrectQanswerQ-
lessQeps,QlessQmovementQdisorders,QlessQsideQeffects;QnonselectivityQofQreceptorQsites,QserotoninQ(5ht)Qbl
ockerQalsoQ(stimulatesQdopamineQreleaseQfurtherQdownQinQtheQbrain),QdopamineQblockerQ(dopamineQisQn
otQblockedQasQfullyQasQconventionalQantipsychotics)



EpsQ-QcorrectQanswerQ-
causedQbyQblockingQofQdopamineQd2QreceptorsQ(risperidoneQinc'dQriskQofQepsQinQhighQdoses)
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