UPDATED ACTUAL Exam Questions and
CORRECT Answers
ACE inhibitors block the production of what in order to lower blood pressure? - CORRECT
ANSWER - Angiotensin II
ARB decrease the influence of what in order to lower blood pressure? - CORRECT
ANSWER - Angiotensin II
How do DRI work? - CORRECT ANSWER - Decrease production of Angiotensin I
What's the name of the only DRI drug available for hypertension? - CORRECT
ANSWER - Aliskiren
What category of diuretic is HCTZ? - CORRECT ANSWER - Thiazide
Which osmotic diuretic has the ability to reduce intracranial pressure when given parentally? -
CORRECT ANSWER - Mannitol
What is the MOA of Loop diuretics? - CORRECT ANSWER - Blocks the reabsorption of
Na and Cl in the ascending loop of Henle
Bumetanide and Torsemide are what type of diuretics? - CORRECT ANSWER - Loop
Diuretics
What is a major adverse effect of Ethacrynic acid? - CORRECT ANSWER - Ototoxicity
, Which diuretic would be best for someone with osteoporosis? - CORRECT ANSWER -
Thiazide diuretic because of its ability to preserve Calcium
What category of diuretic is Metolazone? - CORRECT ANSWER - Thiazide diuretics
What is the MOA of Esplerenone? - CORRECT ANSWER - Inhibits aldosterone receptor,
this leads to increased excretion of water and sodium and retention of potassium
What is the difference between Spironolactone, Esplerenone and Trianterene, Amiloride? -
CORRECT ANSWER - T and A directly block the action of the Sodium Potassium
channel without involving Aldosterone
What category of medication are Captopril, Enalapril, and Lisinipril? - CORRECT
ANSWER - ACE inhibitors
Are ACE inhibitors safe in pregnancy? - CORRECT ANSWER - No, they are teratogenic
Why do ACE inhibitors cause cough? - CORRECT ANSWER - ACE increases
bradykinins causing lung irritation
Why are ACE inhibitors NOT to be given to Renal patients? - CORRECT ANSWER -
ACE inhibitors reverse the constriction of the efferent arteriole hence decreasing the GFR
Medications with the ending -sartan are? - CORRECT ANSWER - ARBS (Angiotensin II
receptor blockers)
What is a benefit of using an ARB instead of an ACE inhibitor? - CORRECT ANSWER -
Less risk of cough due to less bradykinin production in the lungs
What part of the heart does Verapamil Target? - CORRECT ANSWER - Verapamil is a
calcium channel blocker that targets the coronary arteries of the heart. The over all effect is