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nr507 patho derma

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Lecture notes of 8 pages for the course NR 507 / NR507 at Chamberlain College Nursing (dermatology disease)










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Uploaded on
March 8, 2025
Number of pages
8
Written in
2024/2025
Type
Class notes
Professor(s)
Medica
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Dermatological Conditions
Introduction to Psoriasis
Psoriasis is a chronic autoimmune skin condition that speeds up the
growth cycle of skin cells. This results in thick, scaly patches of skin,
often accompanied by itching, burning, or stinging sensations.

The epidermis is the outermost layer of the skin and serves as a protective
barrier against environmental factors, pathogens, and ultraviolet (UV)
radiation.

The dermis is the second layer of the skin, located beneath the epidermis.
The dermis provides structural support to the skin and contains
collagen and elastin fibers, which give the skin its strength and
elasticity.

The hypodermis is the deepest layer of the skin, located beneath the dermis.
The hypodermis acts as a cushioning layer, providing insulation and
energy storage.

One key aspect of psoriasis is the abnormal immune response
involving T cells. In a healthy immune system, T cells help protect the
body against infection and disease. However, these T cells become
overactive in psoriasis and mistakenly attack healthy skin cells. This
immune response triggers a cascade of events in the skin, including
the production of inflammatory cytokines that promote the rapid
growth of skin cells. This rapid growth leads to plagues, the
characteristic raised, red patches of skin covered with silvery
scales.

Plaque psoriasis is the most common form of psoriasis, characterized
by raised, red patches of skin covered with silvery-white scales.
These plaques can vary in size and appear anywhere on the body, but they
are most found on the elbows, knees, scalp, and lower back. Plaque
psoriasis can be itchy and painful and affect the nails, causing them
to become thickened and pitted.

Inverse psoriasis appears in the skin folds and flexures, such as the
armpits, groin, and under the breasts. It presents as smooth, red
patches of skin unlike typical psoriasis plaques. Inverse psoriasis can be

, particularly uncomfortable due to its location in areas of friction and
moisture.

Guttate psoriasis often starts in childhood or young adulthood and is
characterized by small, red, teardrop-shaped lesions that appear on the
trunk, limbs, and scalp. This type of psoriasis is often triggered by bacterial
infections, such as strep throat, and can improve on its own or develop into
chronic plaque psoriasis.

Pustular psoriasis is rare and is characterized by pus-filled blisters
surrounded by red, inflamed skin. Pustular psoriasis can be localized to
certain areas of the body or affect the entire body. This type of psoriasis can
be painful and may be triggered by medications, infections, or other
factors.

Erythrodermic psoriasis is a rare but severe form that affects the
entire body. It is characterized by widespread, fiery redness and
shedding of the skin, often accompanied by severe itching and pain.
Erythrodermic psoriasis can be life-threatening and requires
immediate medical attention.

Risk factors for psoriasis include the following:
 Genetics: Psoriasis tends to run in families, indicating a genetic
predisposition. Individuals with a family history of psoriasis are at
higher risk of developing the condition.

 Immune system: Psoriasis is considered an autoimmune disorder,
where the immune system mistakenly attacks healthy skin cells.
Factors that weaken the immune system, such as infections or
certain medications, can trigger or worsen psoriasis
symptoms.

 Environmental triggers: Certain environmental factors can trigger or
exacerbate psoriasis, including cold or dry weather, skin injuries
(such as cuts, scrapes, or sunburns), and infections (such as
strep throat or skin infections).

 Obesity: Excess weight can increase the risk of developing
psoriasis, and it can also make existing symptoms worse. Obesity
is associated with chronic inflammation, which may contribute to
psoriasis flare-ups.
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