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E. Cells decrease in size
P. Still functional
Physiologic: thymus gland in early childhood
Pathological: disuse - 🧠ANSWER ✔✔Atrophy
E. Increase in cell size
P. Increased workload
Physiologic: weightlifting
Pathologic: cardiomegaly from HTN - 🧠ANSWER ✔✔Hypertrophy
E. Increase in cell number
P. Increased cellular division
Physiologic: liver regeneration
Pathologic: endometrial- usually r/t hormones - 🧠ANSWER ✔✔Hyperplasia
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, E. Cells change in size, shape, organization
P. AKA atypical hyperplasia, a disorderly proliferation
Physiologic: N/A
Pathologic: squamous dysplasia of cervix from HPV - 🧠ANSWER
✔✔Dysplasia
E. one cell type replaced with another
P. reprogramming of stem cells, reversible
Physiologic: N/A
Pathologic: stratified squamous cells in bronchial lining r/t cigarette smoke -
🧠ANSWER ✔✔Metaplasia
E. inadequate oxygenation of tissues
P. decrease in mitochondrial function, decreased production of ATP
increases anaerobic metabolism. eventual cell death.
C.M. hypoxia, cyanosis, cognitive impairment, lethargy - 🧠ANSWER
✔✔Hypoxia injury
E. normal byproduct of ATP production, will overwhelm the mitochondria-
exhaust intracellular antioxidants
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