National Board of Medical Examiners (NBME)
NBME USMLE (United States Medical Licensing
Examination): USMLE Step 1, 2 and 3
NBME CBSSA & NBME CBSE Comprehensive Basic
Science Self- Assessment and Examination
Course Title and Number: NBME CBSSA, NBME CBSE,
and NBME USMLE Exam
Exam Title: NBME
Exam Date: Exam 2025- 2026
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CBSE Exam Review NBME CBSE Comprehensive
Basic Science Examination Review Questions and
Answers | 100% Pass Guaranteed | Graded A+ |
2025- 2026
NBME CBSSA & NBME CBSE Comprehensive
Basic Science Self- Assessment and Examination
NBME USMLE (United States Medical Licensing
Examination): USMLE Step 1, 2 and 3
Read All Instructions Carefully and Answer All the
Questions Correctly Good Luck: -
Treat with high protein diet and niacin.
Niacin (B3) - =Answer>>
Pellagra - =Answer>>
Cladribine - =Answer>> First line treatment of hairy
cell leukemia
Mimics adenosine & inhibits nucleotide metabolism
Resistance to breakdown by adenosine deaminase
during S phase
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Pentostatin - =Answer>> Not a statin! Treatment for
hairy cell leukemia
Inhibits adenosine deaminase-->decreased purine
degradation
Essential tremor - =Answer>> AD nerve disorder
causing slowly progressive, symmetric postural tremors
while moving or trying to move; not usually associated
with Parkinson's
Improves with alcohol; treat w/ propranolol
Atracurium - =Answer>> Skeletal muscle relaxant
that undergoes Hofmann elimination, spontaneous
organ independent breakdown & elimination, along
with a predictable duration of time
Preferred in patients with impaired renal or hepatic
function
Von Gierke's Disease - =Answer>> Type 1 glycogen
storage disease (most common) due to defect in
glucose 6 phosphatase used in the final steps of both
glycogenolysis & gluconeogenesis
Leads to periods of hypoglycemia between meals
requiring continual eating to maintain blood sugar
Additionally accumulation of glucose 6 phosphate
builds up enlarging & damaging the liver over time
Celecoxib - =Answer>> NSAID, COX-2/prostaglandin
synthesis inhibitor
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Can cause vasoconstriction of afferent arterioles &
subsequent renal impairment decreasing clearance,
especially of lithium causing toxicity
Fabry disease - =Answer>> Fabry was a gal that liked
to tri ceramix
Inherited x-linked deficiency of a-galactosidase that
causes accumulation of ceramide trihexoside in tissues
developing into progressive renal failure
Earliest manifestations are cataracts, angiokeratomas,
hypohidrosis & acroparesthesia
I cells - =Answer>> Located in the duodenum &
jejunum where they secrete CCK which increases
pancreatic secretion & slows gastric emptying
S cells - =Answer>> Located in the duodenum &
jejunum where they produce secretin which increases
pancreatic bicarbonate & bile secretion causing
decreased gastric acid secretion & neutralization of
chyme
K cells - =Answer>> Located in the duodenum &
jejunum where they secrete glucose-dependent
insulintropic peptide (GIP) which decreases gastric acid
& increases insulin secretion
Ornithine transcarbamylase deficiency - =Answer>>
Most common urea cycle disorder
X-linked recessive (other urea cycle enzyme
deficiencies are autosomal recessive)
First few days of life, may present later
Excess carbamoyl phosphate converted to orotic acid
High orotic acid in blood and urine
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