National Board of Medical Examiners (NBME)
NBME USMLE (United States Medical Licensing
Examination): USMLE Step 1, 2 and 3
NBME CBSSA & NBME CBSE Comprehensive Basic
Science Self- Assessment and Examination
Course Title and Number: NBME CBSSA, NBME CBSE,
and NBME USMLE Exam
Exam Title: NBME
Exam Date: Exam 2025- 2026
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Examination
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2. Answer all questions.
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4. Ensure all answers are final before submitting the exam.
5. Please answer each question below and click Submit when you
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Learning Resources.
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CBSE Review NBME CBSE Comprehensive Basic
Science Examination Review Questions and
Answers | 100% Pass Guaranteed | Graded A+ |
2025- 2026
NBME CBSSA & NBME CBSE Comprehensive
Basic Science Self- Assessment and Examination
NBME USMLE (United States Medical Licensing
Examination): USMLE Step 1, 2 and 3
Read All Instructions Carefully and Answer All the
Questions Correctly Good Luck: -
what is the purpose/function of the RER? - =Answer>>
synthesis of secretory proteins, protein modification
and transfer
where are steroids synthesized and detoxification of
drugs occur? - =Answer>> in the SMOOTH ER.
what synthesizes cystolic proteins? - =Answer>>
FREE RIBOSOMES
what can be used to calculate GFR? - =Answer>>
inulin (freely filtered) neither reabsorbed nor secreted
**creatine clearance slightly overestimates GFR**
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what can be used to estimate effective renal plasma
flow? - =Answer>> PAH (freely filtered and actively
secreted in the proximal tubule) **underestimates**
where does mannitol work? - =Answer>> on the PCT.
increases tubular fluid osmolarity which increases urine
flow
how does furosemide work? - =Answer>> inhibits the
cotransport system of Na/K at the thick ascending loop
of henle.
how does ethacrynic acid work? - =Answer>> it
basically inhibits the cotransport system of Na/K pump
at the thick ascending loop of henle.
how does HCTZ work? - =Answer>> it ihibits NaCl
reabsorption in the early distal tubule, decreases Ca
excretion
how does the K+ sparing diuretics work? - =Answer>>
spironolactone: aldosterone antagonist in the cortical
collecting tubule. Triameterine, Amiloride block Na
channels at CCT.
Acute myelogenous leukemia - =Answer>> Down
syndrome
Acute myelogenous leukemia - =Answer>>
Myeloperoxidase
Auer rods
T(15,17)- acute PROmyelotic leukemia- retinoic acid
receptor
Hairy cell leukemia - =Answer>> chronic mature B
cell leukemia
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