Chapter 13 Drug Therapy to Decrease Immunity
After organ transplantation, immunosuppressants are given to prevent which of
the
following?
A. nephrotoxicity
B. hepatotoxicity
C. rejection reaction
D. bleeding disorders
The most common cancers that develop with long-term immunosuppression after
organ
transplant are
A. skin cancers and lymphomas
B. cancers of the gastrointestinal tract
C. renal and liver cancers
D. brain and spinal cord cancers
The nurse should instruct the patient taking cyclosporine or tacrolimus that toxic
levels
of the drug may be reached if taken with which of the following beverages that
inhibit
metabolism of the drugs?
A. orange juice
B. coffee
C. grapefruit juice
D. milk
A nurse is caring for a patient who is taking immunosuppressant drugs. The most
critical information to teach the patient is ways
A. to decrease infection
B. to avoid weight gain
C. to maintain a good fluid intake
D. to increase rest and decrease exercise
A patient in an outpatient clinic is taking mycophenolate after a kidney transplant.
Which of the following over-the-counter products is likely to interfere with the
activity of this immunosuppressant?
A. diphenhydramine, used for itchy mosquito bites
B. acetaminophen, used for a tension headache
, C. magnesium/aluminum hydroxide, used for heartburn
D. benzocaine/dextromethorphan throat lozenges, used for throat irritation
A woman is taking leflunomide for rheumatoid arthritis, and her provider monitors
her
laboratory results on a regular basis. Which of the following laboratory findings
indicates that the patient is experiencing an adverse effect?
A. increased red blood cell count
B. decreased creatinine
C. increased white blood cell count
D. decreased liver enzymes
Monoclonal antibodies are engineered to specifically target a certain antigen,
such as one found on cancer cells. Which of the following actions by monoclonal
antibodies have demonstrated effectiveness in cancer therapy? (Check all that
apply.)
A. make the cancer cell more visible to the immune system
B. block growth signals
C. increase growth of new blood vessels
D. deliver radiation or chemotherapy to cancer cells
A client has developed a wound infection and leukocytes are leaving the
bloodstream to perform phagocytosis on pathogens. What white cells are most
likely performing this function?
A. Basophils
B. Neutrophils
C. Monocytes
D. Eosinophils
A client is experiencing an allergy to a penicillin antibiotic. What immunoglobulin
(Ig) will most directly relate to this immune response?
A. IgA
B. IgM
C. IgE
D. IgG
A 23-year-old man has received a recent diagnosis of appendicitis following 24
hours of acute abdominal pain. The nurse providing care for the man is
explaining that while unpleasant, the inflammation of his appendix is playing a
role in his body's fight against the underlying infectious process. Which teaching
point should the nurse not teach to the patient?
A. "Inflammation ultimately aids in eliminating the initial cause of the cell injury in your
appendix."
B. "Inflammation will start your body on the path to growing new, healthy tissue at the
After organ transplantation, immunosuppressants are given to prevent which of
the
following?
A. nephrotoxicity
B. hepatotoxicity
C. rejection reaction
D. bleeding disorders
The most common cancers that develop with long-term immunosuppression after
organ
transplant are
A. skin cancers and lymphomas
B. cancers of the gastrointestinal tract
C. renal and liver cancers
D. brain and spinal cord cancers
The nurse should instruct the patient taking cyclosporine or tacrolimus that toxic
levels
of the drug may be reached if taken with which of the following beverages that
inhibit
metabolism of the drugs?
A. orange juice
B. coffee
C. grapefruit juice
D. milk
A nurse is caring for a patient who is taking immunosuppressant drugs. The most
critical information to teach the patient is ways
A. to decrease infection
B. to avoid weight gain
C. to maintain a good fluid intake
D. to increase rest and decrease exercise
A patient in an outpatient clinic is taking mycophenolate after a kidney transplant.
Which of the following over-the-counter products is likely to interfere with the
activity of this immunosuppressant?
A. diphenhydramine, used for itchy mosquito bites
B. acetaminophen, used for a tension headache
, C. magnesium/aluminum hydroxide, used for heartburn
D. benzocaine/dextromethorphan throat lozenges, used for throat irritation
A woman is taking leflunomide for rheumatoid arthritis, and her provider monitors
her
laboratory results on a regular basis. Which of the following laboratory findings
indicates that the patient is experiencing an adverse effect?
A. increased red blood cell count
B. decreased creatinine
C. increased white blood cell count
D. decreased liver enzymes
Monoclonal antibodies are engineered to specifically target a certain antigen,
such as one found on cancer cells. Which of the following actions by monoclonal
antibodies have demonstrated effectiveness in cancer therapy? (Check all that
apply.)
A. make the cancer cell more visible to the immune system
B. block growth signals
C. increase growth of new blood vessels
D. deliver radiation or chemotherapy to cancer cells
A client has developed a wound infection and leukocytes are leaving the
bloodstream to perform phagocytosis on pathogens. What white cells are most
likely performing this function?
A. Basophils
B. Neutrophils
C. Monocytes
D. Eosinophils
A client is experiencing an allergy to a penicillin antibiotic. What immunoglobulin
(Ig) will most directly relate to this immune response?
A. IgA
B. IgM
C. IgE
D. IgG
A 23-year-old man has received a recent diagnosis of appendicitis following 24
hours of acute abdominal pain. The nurse providing care for the man is
explaining that while unpleasant, the inflammation of his appendix is playing a
role in his body's fight against the underlying infectious process. Which teaching
point should the nurse not teach to the patient?
A. "Inflammation ultimately aids in eliminating the initial cause of the cell injury in your
appendix."
B. "Inflammation will start your body on the path to growing new, healthy tissue at the
