COMSAE: Neuro Exam Questions and Answers 2025/2026( A+ GRADED 100% VERIFIED).

COMSAE: Neuro
Frontal lobe lesion
Lesion results in:
Disinhibition and deficits in concentration, orientation, judgement. May have re-emergence of
primitive reflexes


Frontal eye fields
Lesion results in:

Eyes will loos toward brain lesion (i.e. away from side of hemiplegia)

-E.g. MCA stroke




Paramedian pontine reticular formation (PPRF)
Lesion results in:

Eyes will look away from brain lesion (i.e. toward side of hemiplegia)




Medial longitudinal fasciculus
Lesion results in:

Internuclear ophthalmoplegia

-Impaired aDduction of ipsilateral eye

-Nystagmus of contralateral eye w/ aBduction

Example: Multiple sclerosis

, Dominant parietal cortex
Lesion results in:

Agraphia (can't write), acalculia (can't process numbers), finger agnosia (can't recognize
fingers), left-right disorientation

Example: Gerstmann syndrome




Nondominant parietal cortex
Lesion results in:

Agnosia (can't recognize things) of the contralateral side of the world

Example: Hemispatial neglect syndrome




Hippocampus
Lesion results in:

Anterograde amnesia (inability to make new memories)




Basal ganglia
Lesion results in:

Tremor at rest, chorea (jerky movements), athetosis (slow, involuntary, writing movements)

Examples:

-Parkinson disease: ↓ dopamine

-Huntington disease: ↑ dopamine, ↓ ACh/GABA

-Wilson disease: Cu accumulation




subthalamic nucleus
Lesion results in: