NURS 474a Exam 2 (other-2022) Questions and Correct Answers/ Latest Update / Already Graded

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NURS 474a Exam 2 (other-2022)
Questions and Correct Answers/ Latest
Update / Already Graded
Cyclooxygenase Inhibitor Main Effects


Ans: -can suppress inflammation


-relieve pain


-reduce fever




Function of COX-1


Ans: -gastric protection


-maintenance of submucosal blood flow


-platelet aggregation


-maintenance of renal function and perfusion




Inhibition of COX-1

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Ans: -gastric ulceration


-increased bleeding


-protection against MI


-renal impairment




Function of COX-2


Ans: -vasodilation


-maintenance of renal function and perfusion


-inflammation


-pain (injured tissue and brain)


-fever


-promotes colorectal cancer




Inhibition of COX-2

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Ans: -vasoconstriction


-renal impairment


-reduced inflammation


-analgesia (injured tissue and brain)


-reduced fever


-protects against colorectal cancer




First Generation NSAIDs


Ans: Ex: Aspirin and Ibuprofen


-inhibits both COX-1 and COX-2




Aspirin

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Ans: Irreversible COX inhibitor.


First Gen NSAID


Unique in that:


-protect against Myocardial Infarction (MI)


-protect against stroke


Adverse Effects


-gastrointestinal issues


-bleeding


-renal impairment


-salicylism


-reye's syndrome


Should not be used during pregnancy.




Salicylism