PC 707 Module 1 2025 update|comprehensive
questions and verified answers (complete
solutions) Exam|GRADE A+!!
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Terms in this set (507)
Are there any standards No standards
for potency, efficacy, and
purity for herbal
medicines?
helpful in tx some common IBS symptoms (abd pain
peppermint oil
and gas)
what is the main adverse Heartburn
effect of peppermint
When do you avoid Hx of MI, GI bleed, elevated BP
Acetaminophen (APAP)?
Area under the plasma concentration time curve
AUC it is the amount of drug in the blood after a dose is
given
a measure of avalibility
butterburr for headaches
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development of fetal compartment.
So,
plasma and total body water increase (plasma
50%)therefore, serum drug levels decrease and you
Vd (volume distribution) may need to increase the dose of hydrophilic meds
in pregnancy
albumin levels decrease and serum albumin binding
decreases.... this means that there are more
unbound drugs and there is an increased transport
of free drugs into the fetal compartment
usually first pass is not altered, but there is an
increase in metabolic enzymes so drug doses may
need to be increased.
at the same time, some metabolic enzymes are
decreased so some drugs may need to be reduced
and monitor for toxicity
metabolism in pregnancy
there is increased estrogen and progesterone:
These may increase metabolization of some drugs
and decrease others
decreased albumin levels increase the amounts of
unbound drugs and increase clearance of the drugs
not affordable
do not understand directions of use
reasons for medication
side effects
nonadherence (5)
inconvenient regimen
decide they dont need it
What does the American 50% do not take their meds
College of Preventive less than 70% fill their prescriptions
Medicine say about only 25-30% take the meds as ordered
medication compliance
increased renal blood flow and GFR increase the
excretion/clearance in
clearance of medications that undergo renal
pregnancy
clearance
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Maximum 4 g daily
Acetaminophen dosage 650mg q4
for adults/day? 1000 mg qid
Criteria for a drug to be safe, low misuse, self diagnose, self manage, labeled
OTC?
How many OTC products over 100,000
are there?
What OTC drug causes Antihistamine; specifically 1st gen
confusion in the elderly?
What 6 different Antihistamine, anti-tussives, H2 antagonists, NSAIDs,
components are found in anti-motility, alcohol
common OTC
medicines?
Why is it important to ask side effects, adverse reactions, and drug
patients about OTC interactions
medications?
Common uses of NSAIDs Fever reducer, pain
Major side effect of Upper GI bleed (UGIB)
NSAIDs
Who should use NSAIDs elderly and hx of GI bleed
with caution?
When taking NSAIDs with Corticosteroids, anticoagulants, aspirin, alcohol
what other 4
drugs/products further
increases the risk of GI
bleed?
What 3 groups of Heart failure, severe kidney disease; asthma
patients should NSAIDs
be AVOIDED?
what are the MI, CVA, emboli, GI bleeds, renal failure/disease
risks/conditions (5)
associated with long
term use of NSAIDs?
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What other class of drugs COX-2 inhibitors (only prescribed for pts with hx of
decreases the risk of GI GI bleed)
bleed compared to
NSAIDs?
If pts are taking ASA for NSAIDs bc it interferes with ASA's cardioprotective
prophylaxis, what drug effects
class should they avoid?
If pt needs long term PPI, H2RA, or cytotec
NSAIDs, what classes (3)
should be prescribed
instead?
What condition could HTN
worsen when taking
NSAIDs
What risk is associated GI bleed
with ASA?
What medication classes Anticoagulants, antiplatelets
can increase the risk of
GI bleed with patients
taking ASA?
How many days does up to 7 days due to acetylation process
ASA suppress platelet
production?
What symptom would Tinnitus
cause pt to discontinue
ASA use immediately?
What age group should Children <16 with viral illness
ASA be avoided?
If ASA is given to children Reye's syndrome
with a viral illness, what
syndrome can result?
What is the post-MI and 81 mg
post-cardiovascular
dose?
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