Five. Which medicine would be the best choice for a patient who has an eGFR <30ml/min?
A. Epclusa (velpatasvir/sofosbuvir)
b. Vosevi (velpatasvir/sofosbuvir/voxilaprevir)
c. Harvoni (ledipasvir/sofosbuvir)
d. Mavyret (glecaprevir/pibrentasvir) - ANS-d. Mavyret (glecaprevir/pibrentasvir)
A 30 yr vintage lady MS patient states she's considering starting a family. What could you
inform her approximately the remedy alternatives for MS and being pregnant?
A. Aubagio (teriflunomide) has no pregnancy precautions and would be an excellent option
for
her.
B. Aubagio (teriflunomide) has been proven to purpose delivery defects and might soak up
to two
months to be removed from the body.
C. Copaxone (glatiramer) is rated class B in pregnancy and a probable option for
treatment during pregnancy.
D. Betaseron (interferon - ANS-c. Copaxone (glatiramer) is rated class B in being pregnant
and a probable option for
remedy at some point of pregnancy.
A forty five y/o, 200lb patient is suffering with excessive dermatitis and the provider desires
to probably
start a biologic. Which medicine might you suggest?
A. Protopic (tacrolimus)
b. Humira (adalimumab)
c. Stelara (ustekinumab)
d. Dupixent (dupilumab) - ANS-d. Dupixent (dupilumab)
A 45 yr old male with pancreatic most cancers is given a prescription for Tarceva (erlotinib).
He
states that he currently smokes about one percent of cigarettes a day. How need to you
consult the
affected person?
A. Smoking increases Tarceva stages and he'll experience more side outcomes if he
maintains to smoke
b. Smoking decreases Tarceva stages and the medicine will be less effective if he
maintains to smoke
c. Tarceva levels aren't tormented by tobacco use
d. Smoking at the same time as taking Tarceva is contraindicated - ANS-b. Smoking
decreases Tarceva tiers and the medication may be much less effective if he
continues to smoke
A 56 y/o M is recognized with metastatic, castration‐resistant prostate most cancers and the
provider
asks which oral antiandrogen you advise. He has a beyond scientific history which include
hypertension and poorly controlled kind II diabetes. What is your recommendation?
, A. Zytiga (abiraterone acetate) 1000mg as soon as each day with prednisone
b. Xtandi (enzalutamide) 160mg as soon as day by day with prednisone
c. Xtandi (enzalutamide) 160mg once every day
d. Zytiga (abiraterone acetate) 1000mg as soon as every day - ANS-c. Xtandi
(enzalutamide) 160mg as soon as every day
A 56 y/o, 140lb affected person with psoriasis may be beginning Stelara (ustekinumab),
however the provider
desires to affirm the dosing of the drugs. What starting dose would you advocate?
A. Inject forty five mg subcutaneously at weeks 0 and four, observed via forty five mg every
12 weeks
b. Inject 90 mg subcutaneously at weeks 0 and 4, followed by means of 90 mg every 12
weeks
c. Infuse 260 mg IV over at the least 1 hour as a unmarried dose, accompanied 8 weeks
later with 90 mg
subcutaneously each 8 weeks
d. Infuse 520 mg IV over at least 1 hour as a single dose, followed eight weeks later with
ninety mg
subcutaneously each eight weeks - ANS-a. Inject forty five mg subcutaneously at weeks
zero and 4, followed by way of 45 mg each 12 weeks
A patient calls the pharmacy and states that their 2d Humira (adalimumab) pen changed into
left on
their kitchen counter overnight after injecting. How could you suggest the affected person?
A. Humira is stored at room temperature and this need to now not be an trouble
b. Humira is stored inside the refrigerator, however the medication is strong for up to a few
months at room temperature.
C. Humira is saved in the fridge, however the remedy is stable for up to fourteen
days at room temperature.
D. Humira is stored within the fridge and ought to therefore be discarded - ANS-c. Humira is
stored inside the fridge, however the medicine is strong for up to fourteen
days at room temperature.
A affected person calls to speak about her side outcomes from Tecfidera (dimethyl
fumarate). Every time she
takes her Tecfidera she has flushing. What would you suggest to this affected person?
A. Flushing is not a facet effect of Tecfidera.
B. She have to take on an empty stomach to lessen the flushing.
C. Taking the Tecfidera with meals and taking an aspirin earlier than her dose can help
lessen
flushing.
D. Flushing is a not unusual facet impact that does not get better through the years. - ANS-c.
Taking the Tecfidera with meals and taking an aspirin earlier than her dose can assist reduce
flushing.
A patient to your health center has a new prognosis of continual phase Philadelphia
chromosome superb
CML and the provider desires to order remedy with Tasigna (nilotinib). During your drug
evaluation, you word the patient is on fluconazole. Which of the following is actual
concerning the
interaction among Tasigna and fluconazole?
A. There isn't any interaction, no change is vital