Unit 1 MLS Review Exam- RBC 1
What is the RBC maturation series? - ✔️✔️rubriblast-pronormoblast, prorubricyte-
basophilic normoblast, rubricyte- polychromatophilic normoblast, metarubricyte-
orthochromic normoblast, retic, mature cell
What is the last cell in the RBC maturation series capable of mitosis? - ✔️✔️rubricyte-
polychromatophilic normoblast
What is unique about the metarubricyte nucleus? - ✔️✔️pyknotic
What demographic has the highest normal WBC, RBC, hgb, and hct? - ✔️✔️newborns
In what month of embryonic maturation does BM become the main region of
hematopoiesis? - ✔️✔️5th
What is the most common WBC seen in healthy BM? - ✔️✔️metamyelocytes
What demographic has the lowest normal RBC, hgb, and hct? - ✔️✔️6mo-1yr
What components make up a hgb molecule? - ✔️✔️4 moles of heme + one mole of
globin
What form of iron is the body able to use? - ✔️✔️ferrous - Fe2+
What factors effect hgb's ability to transport and deliver O2 to tissues? - ✔️✔️pH,
temperature, ionic strength, and DPG
What is the bohr effect? - ✔️✔️shift in saturation curve as pH shifts
What is the function of DPG? - ✔️✔️decreases hgb's affinity for O2
What factors cause a decrease in hgb's affinity for O2? - ✔️✔️decreased pH, high
temps, increased DPG
What factors cause an increase in hgb's affinity for O2? - ✔️✔️increased pH, low
temps, decreased DPG
What is the RBC maturation series? - ✔️✔️rubriblast-pronormoblast, prorubricyte-
basophilic normoblast, rubricyte- polychromatophilic normoblast, metarubricyte-
orthochromic normoblast, retic, mature cell
What is the last cell in the RBC maturation series capable of mitosis? - ✔️✔️rubricyte-
polychromatophilic normoblast
What is unique about the metarubricyte nucleus? - ✔️✔️pyknotic
What demographic has the highest normal WBC, RBC, hgb, and hct? - ✔️✔️newborns
In what month of embryonic maturation does BM become the main region of
hematopoiesis? - ✔️✔️5th
What is the most common WBC seen in healthy BM? - ✔️✔️metamyelocytes
What demographic has the lowest normal RBC, hgb, and hct? - ✔️✔️6mo-1yr
What components make up a hgb molecule? - ✔️✔️4 moles of heme + one mole of
globin
What form of iron is the body able to use? - ✔️✔️ferrous - Fe2+
What factors effect hgb's ability to transport and deliver O2 to tissues? - ✔️✔️pH,
temperature, ionic strength, and DPG
What is the bohr effect? - ✔️✔️shift in saturation curve as pH shifts
What is the function of DPG? - ✔️✔️decreases hgb's affinity for O2
What factors cause a decrease in hgb's affinity for O2? - ✔️✔️decreased pH, high
temps, increased DPG
What factors cause an increase in hgb's affinity for O2? - ✔️✔️increased pH, low
temps, decreased DPG
