Exam Questions and CORRECT Answers
immune system - CORRECT ANSWER - complex body defines system- protects body
against bacteria, viruses, toxins and parasites
innate system - CORRECT ANSWER - -present at birth
-not antigen specific
-present at all times
-does not improve with
repeated exposure to infectious agent
adaptive immune system - CORRECT ANSWER - -develops throughout life
-antigen specific
-lag time between infection and response
-memory develops- provides lifelong immunity to reinfection
immune response - CORRECT ANSWER - defend the life of the individual - by
identifying foreign substances in body and developing defence against them
host response - CORRECT ANSWER - The way that an individual's body responds to an
infection
leukocytes - CORRECT ANSWER - -act like independent single-cell organisms
-can move through tissues and capture micro-organisms on their own
-2 types important in perio disease: PMNs, Moncytes/macrophages
phagocytosis - CORRECT ANSWER - process by which leukocytes engulf and digest
microorganisms
,polymorphonuclear leukocytes - CORRECT ANSWER - (PMNs)
-neutrophils
- rapid responders- 1st line of defence
- capture/ destroy bacterial invaders
-short-lived
what attracts leukocytes to an infection site - CORRECT ANSWER - PMNs are attracted
to bacteria by chemotaxis
lysosomes - CORRECT ANSWER - strong bactericidal and digestive enzymes in PMN
-perio pathogens are effectively destroyed by PMNs
monocytes/macrophages - CORRECT ANSWER - monocytes:in the bloodstream
macrophages: in the tissues
-slower to arrive at infection site than PMNs
-surround/destroy bacteria
-long-lived cells in chronic inflammation
lymphocytes - CORRECT ANSWER - small leukocytes- help defend body
2 types: B cells, t cells
B lymphocytes - CORRECT ANSWER - B Cells
makes antibodies and pour into bloodstream
2 types: plasma/ memory b cells
antibodies - CORRECT ANSWER - y shaped proteins
, y binds w outside of b celll
-other end of y binds to a MO and kills it
antibodies - CORRECT ANSWER - are known collectively as immunoglobulins
T lymphocytes - CORRECT ANSWER - T cells
intensify the response of other immune cells to bacterial invasion
-produce CYTOKINES- further stimulate immune response
cytokine - CORRECT ANSWER - protein secreted by cells and affects behaviour of
nearby cells
regulate behaviour of immune cells
complement system - CORRECT ANSWER - series of protons circulating in blood:
-facilitate phagocytosis of bacteria
-kill bacteria directly - form pores in bacterial cell membrane
function of complement system - CORRECT ANSWER - • Destruction of pathogens
• Opsonization of pathogens
• Recruitment of phagocytes
• Immune clearance
trans-endothelial migration - CORRECT ANSWER - leukocytes push their way between
endothelial cells and enter connective tissue
migration - CORRECT ANSWER - leukocytes travel through the bloodstream to fight an
infection