,Chapter 1. THE FOUNDATIONAL CONCEPTS OF CLINICAL
p p p p p p
PRACTICE
p
1. The characteristic, localized cardinal signs of acute inflammation include:
p p p p p p p p
A) fever.
B) fatigue.
C) redness.
D) granuloma.
2. The vascular, hemodynamic stage of acute inflammation is initiated by
p p p p p p p p p
momentary vasoconstriction followed by vasodilation that causes
p p p p p p p
localized:
p
A) bleeding.
B) congestion.
C) pale skin. p
D) coolness.
3. The cellular stage of acute inflammation is marked by the movement of
p p p p p p p p p p p
leukocytes into the area. Which of the following cells arrives early in great
p p p p p p p p p p p p p
numbers?
p
A) Basophils
B) Lymphocytes
C) Neutrophils
D) Platelets
4. The phagocytosis process involves three distinct steps. What is the initial
p p p p p p p p p p
step in the process?
p p p p
A) Engulfment
B) Intracellular killing p
C) Antigen margination p
,D) Recognition and adherence p p
5. Which of the following mediators of inflammation causes increased capillary
p p p p p p p p p
permeability and pain?
p p p
A) Serotonin
B) Histamine
C) Bradykinin
D) Nitric oxide p
6. Inflammatory exudates are a combination of several types. Which of the
p p p p p p p p p p
pfollowing exudates is composed of enmeshed necrotic cells?
p p p p p p p
A) Serous
B) Fibrinous
C) Suppurative
D) Membranous
7. The acute-phase systemic response usually begins within hours of the onset
p p p p p p p p p p
of inflammation and includes:
p p p p
A) fever and lethargy.
p p
B) decreased C-reactive protein. p p
C) positive nitrogen balance. p p
D) low erythrocyte sedimentation rate.
p p p
8. In contrast to acute inflammation, chronic inflammation is characterized by
p p p p p p p p p
pwhich of the following phenomena?
p p p p
A) Profuse fibrinous exudation p p
B) A shift to the left of granulocytes
p p p p p p
C) Metabolic and respiratory alkalosis p p p
D) Lymphocytosis and activated macrophages p p p
, 9. Exogenous pyrogens (interleukin-1) and the presence of bacteria in the blood
p p p p p p p p p p
lead to the release of endogenous pyrogens that:
p p p p p p p p
A) stabilize thermal control in the brain.
p p p p p
B) produce leukocytosis and anorexia. p p p
C) block viral replication in cells.
p p p p
D) inhibit prostaglandin release. p p
10 An older adult patient has just sheared the skin on her elbow while attempted
p p p p p p p p p p p p p
. to boost herself up in bed, an event that has precipitated acute inflammation
p p p p p p p p p p p p
pin the region surrounding the wound. Which of the following events will
p p p p p p p p p p p
poccur during the vascular stage of the patients inflammation?
p p p p p p p p
A) Outpouring of exudate into interstitial spaces p p p p p
B) Chemotaxis
C) Accumulation of leukocytes along the epithelium p p p p p
D) Phagocytosis of cellular debris p p p
11 Which of the following individuals most likely has the highest risk of
p p p p p p p p p p p
. experiencing chronic inflammation? p p
A) A patient who has recently been diagnosed with type 2 diabetes
p p p p p p p p p p
B) A patient who is a carrier of an antibiotic-resistant organism
p p p p p p p p p
C) A patient who is taking oral antibiotics for an upper respiratory infection
p p p p p p p p p p p
D) A patient who is morbidly obese and who has a sedentary lifestyle
p p p p p p p p p p p
12 Which of the following core body temperatures is within normal range?
p p p p p p p p p p
.
A) 35.9C (96.6F) p
B) 38.0C (100.4F) p
C) 35.5C (95.9F) p
D) 37.3C (99.1F) p
p p p p p p
PRACTICE
p
1. The characteristic, localized cardinal signs of acute inflammation include:
p p p p p p p p
A) fever.
B) fatigue.
C) redness.
D) granuloma.
2. The vascular, hemodynamic stage of acute inflammation is initiated by
p p p p p p p p p
momentary vasoconstriction followed by vasodilation that causes
p p p p p p p
localized:
p
A) bleeding.
B) congestion.
C) pale skin. p
D) coolness.
3. The cellular stage of acute inflammation is marked by the movement of
p p p p p p p p p p p
leukocytes into the area. Which of the following cells arrives early in great
p p p p p p p p p p p p p
numbers?
p
A) Basophils
B) Lymphocytes
C) Neutrophils
D) Platelets
4. The phagocytosis process involves three distinct steps. What is the initial
p p p p p p p p p p
step in the process?
p p p p
A) Engulfment
B) Intracellular killing p
C) Antigen margination p
,D) Recognition and adherence p p
5. Which of the following mediators of inflammation causes increased capillary
p p p p p p p p p
permeability and pain?
p p p
A) Serotonin
B) Histamine
C) Bradykinin
D) Nitric oxide p
6. Inflammatory exudates are a combination of several types. Which of the
p p p p p p p p p p
pfollowing exudates is composed of enmeshed necrotic cells?
p p p p p p p
A) Serous
B) Fibrinous
C) Suppurative
D) Membranous
7. The acute-phase systemic response usually begins within hours of the onset
p p p p p p p p p p
of inflammation and includes:
p p p p
A) fever and lethargy.
p p
B) decreased C-reactive protein. p p
C) positive nitrogen balance. p p
D) low erythrocyte sedimentation rate.
p p p
8. In contrast to acute inflammation, chronic inflammation is characterized by
p p p p p p p p p
pwhich of the following phenomena?
p p p p
A) Profuse fibrinous exudation p p
B) A shift to the left of granulocytes
p p p p p p
C) Metabolic and respiratory alkalosis p p p
D) Lymphocytosis and activated macrophages p p p
, 9. Exogenous pyrogens (interleukin-1) and the presence of bacteria in the blood
p p p p p p p p p p
lead to the release of endogenous pyrogens that:
p p p p p p p p
A) stabilize thermal control in the brain.
p p p p p
B) produce leukocytosis and anorexia. p p p
C) block viral replication in cells.
p p p p
D) inhibit prostaglandin release. p p
10 An older adult patient has just sheared the skin on her elbow while attempted
p p p p p p p p p p p p p
. to boost herself up in bed, an event that has precipitated acute inflammation
p p p p p p p p p p p p
pin the region surrounding the wound. Which of the following events will
p p p p p p p p p p p
poccur during the vascular stage of the patients inflammation?
p p p p p p p p
A) Outpouring of exudate into interstitial spaces p p p p p
B) Chemotaxis
C) Accumulation of leukocytes along the epithelium p p p p p
D) Phagocytosis of cellular debris p p p
11 Which of the following individuals most likely has the highest risk of
p p p p p p p p p p p
. experiencing chronic inflammation? p p
A) A patient who has recently been diagnosed with type 2 diabetes
p p p p p p p p p p
B) A patient who is a carrier of an antibiotic-resistant organism
p p p p p p p p p
C) A patient who is taking oral antibiotics for an upper respiratory infection
p p p p p p p p p p p
D) A patient who is morbidly obese and who has a sedentary lifestyle
p p p p p p p p p p p
12 Which of the following core body temperatures is within normal range?
p p p p p p p p p p
.
A) 35.9C (96.6F) p
B) 38.0C (100.4F) p
C) 35.5C (95.9F) p
D) 37.3C (99.1F) p