Complete Solutions
Clomiphene (Clomid) Correct Answers -SERM, used for
infertility to induce ovulation
Danazol (Danocrine) Correct Answers -weak progestational,
androgenic, and glucocorticoid effects
-suppresses ovarian function, inhibits midcycle surge of LH &
FSH to treat endometriosis, also used for hematologic disorders
-ADR: weight gain, edema, decreased breast size, acne/oily skin,
hair growth, deepening of the voice
Dinoprostone (Cervidil) Correct Answers -prostaglandin E2
analog given vaginally to facilitate cervical ripening and induce
labor
-it is removed when labor begins or after 12 hours
-must monitor fetal HR during use
Folic acid use in pregnancy Correct Answers All women who
plan to become pregnant or are pregnant should take 400 mcg
daily to prevent neural tube defects.
How can endometrial hyperplasia be prevented? Correct
Answers co-administration with a progestin
How can oral combination estrogens and progestins differ in
dosing? Correct Answers -monophasic: constant dosage of
both during menstrual cycle
-biphasic: dosage of one or both components changed once
during the cycle
, -triphasic: dosage of one or both components changed twice
during the cycle
How do you manipulate oral contraception if breakthrough
bleeding continues after 3 months of initiation of therapy?
Correct Answers -If bleeding is on days 1-14, it indicates
estrogen deficiency, so raise the estrogen dose.
-If bleeding is on days 15-21, it indicates progestin deficiency,
so increase the progestin dose.
How is estrogen used to treat primary hypogonadism? Correct
Answers -can replace deficiency in patients w/ developmental
failure of ovaries, premature menopause, castration, or
menopause
-can begin at 11-13 yrs to stimulate secondary sex
characteristics and menses, prevent osteoporosis
-given on days 1-21 each month to simulate normal E2 levels
How is the Nuvaring used? Correct Answers The ring stays in
the vagina for 21 days, removed for 7 (when menses occurs)
How long should you wait to get pregnant after stopping oral
contraception? Correct Answers 3 regular menstrual cycles
How often is the Estonogestrel (Implanon) replaced? Correct
Answers every 3 years
Levonorgestrel (Mirena) Correct Answers -IUD that lasts for 5
years
-prevents pregnancy by stopping the release of the egg from the
ovary, inhibiting sperm from fertilizing the egg, thinning the