NURS 5315 UTA EXAM |2025| QUESTIONS WITH
VERIFIED CORRECT ANSWERS
QUESTION>give CM and an example of coagulopathy hemorrhage - ANSWER~CM- joint bleeding, tissue
hematomas, large spontaneous central ecchymosis, delayed bleeding after surgery, trauma or injury
DIC
QUESTION>give CM and example of thrombocytopenia hemorrhage - ANSWER~CM- mucosal bleeding,
epistaxis, GI or GU bleed, oral bleeding, hemoptysis, heavy menses, immediate bleeding after trauma,
possible petechiae
ITP
QUESTION>what are causes of thrombocytopenia - ANSWER~post-op hemodilution (nadir 2-4 days),
splenomegaly, HIV, bone marrow failure, hemolysis, multiple medications
QUESTION>Primary Immune Thrombocytopenic Purpura- patho and CM - ANSWER~immune mediated
destruction of platelets- primary or secondary (caused by another etiology)
CM- petechiae, purpura, easy bruising, epistaxis, gingival bleeding, menorrhagia
CM vary with age- worse in elderly
QUESTION >HIV EIA (3rd generation immunoassay) - ANSWER~can use urine, saliva, or serum (most
accurate), need to wait until 12 weeks post exposure to see antibodies, >99% accurate
4th generation immunoassay- "gold standard"
measures P24 antigen
can test 10 days post exposure
QUESTION>Mast cell - ANSWER~Cellular bags of granules located in loose connective tisssue close to
blood vessels. Activation initiates inflammatory process.
QUESTION>Histamine - ANSWER~Causes vasodilation, increases vascular permeability, increases blood
flow to the site of injury- causes erythema and swelling.
, QUESTION>Cytokines - ANSWER~Soluble factors that contribute to the regulation of innate or adaptive
resistance by affecting other neighboring cells. Can be pro-inflammatory or anti-inflammatory. Can react
quickly or be more delayed.
QUESTION>Leukotrines - ANSWER~Released when mast cells degranulate, prolong the inflammatory
process. Cause vasodilation, attract neutrophils, monocytes, and eosinophils.target of inhibition for
singular.
QUESTION>Prostaglandins - ANSWER~Released when mast cells degranulate, are produced by the
arachidonic pathway. Cause vasodilation, platelet aggregation at site of injury, pain, and fever.
QUESTION>Chemotactic factors - ANSWER~Biochemical substance that attracts leukocyte to the site of
inflammation
QUESTION>Neutrophils - ANSWER~Predominant leukocyte at work during the early stages of acute
inflammation
QUESTION>Monocytes - ANSWER~Become macrophages when entering the tissue, responsible for
presenting antigens to the CD4 cell which triggers T-cell immunity and B-cell immunity.
Releases additional cytokines IL1, IL6, TNF.
QUESTION>Cytokine IL1 function - ANSWER~Causes fever, activates phagocytes & lymphocytes and also
increases the release of IL6a
QUESTION>Cytokine IL6 function - ANSWER~Stimulates production of acute phase reactants and
promotes growth and stimulation of RBCs
QUESTION>Cytokine TNF function - ANSWER~Causes fever, increases synthesis of proinflammatory
proteins by liver, causes muscle wasting, induces thrombosis
QUESTION>Cytokine growth factor function - ANSWER~Promotes production and maturation of
neutrophils
VERIFIED CORRECT ANSWERS
QUESTION>give CM and an example of coagulopathy hemorrhage - ANSWER~CM- joint bleeding, tissue
hematomas, large spontaneous central ecchymosis, delayed bleeding after surgery, trauma or injury
DIC
QUESTION>give CM and example of thrombocytopenia hemorrhage - ANSWER~CM- mucosal bleeding,
epistaxis, GI or GU bleed, oral bleeding, hemoptysis, heavy menses, immediate bleeding after trauma,
possible petechiae
ITP
QUESTION>what are causes of thrombocytopenia - ANSWER~post-op hemodilution (nadir 2-4 days),
splenomegaly, HIV, bone marrow failure, hemolysis, multiple medications
QUESTION>Primary Immune Thrombocytopenic Purpura- patho and CM - ANSWER~immune mediated
destruction of platelets- primary or secondary (caused by another etiology)
CM- petechiae, purpura, easy bruising, epistaxis, gingival bleeding, menorrhagia
CM vary with age- worse in elderly
QUESTION >HIV EIA (3rd generation immunoassay) - ANSWER~can use urine, saliva, or serum (most
accurate), need to wait until 12 weeks post exposure to see antibodies, >99% accurate
4th generation immunoassay- "gold standard"
measures P24 antigen
can test 10 days post exposure
QUESTION>Mast cell - ANSWER~Cellular bags of granules located in loose connective tisssue close to
blood vessels. Activation initiates inflammatory process.
QUESTION>Histamine - ANSWER~Causes vasodilation, increases vascular permeability, increases blood
flow to the site of injury- causes erythema and swelling.
, QUESTION>Cytokines - ANSWER~Soluble factors that contribute to the regulation of innate or adaptive
resistance by affecting other neighboring cells. Can be pro-inflammatory or anti-inflammatory. Can react
quickly or be more delayed.
QUESTION>Leukotrines - ANSWER~Released when mast cells degranulate, prolong the inflammatory
process. Cause vasodilation, attract neutrophils, monocytes, and eosinophils.target of inhibition for
singular.
QUESTION>Prostaglandins - ANSWER~Released when mast cells degranulate, are produced by the
arachidonic pathway. Cause vasodilation, platelet aggregation at site of injury, pain, and fever.
QUESTION>Chemotactic factors - ANSWER~Biochemical substance that attracts leukocyte to the site of
inflammation
QUESTION>Neutrophils - ANSWER~Predominant leukocyte at work during the early stages of acute
inflammation
QUESTION>Monocytes - ANSWER~Become macrophages when entering the tissue, responsible for
presenting antigens to the CD4 cell which triggers T-cell immunity and B-cell immunity.
Releases additional cytokines IL1, IL6, TNF.
QUESTION>Cytokine IL1 function - ANSWER~Causes fever, activates phagocytes & lymphocytes and also
increases the release of IL6a
QUESTION>Cytokine IL6 function - ANSWER~Stimulates production of acute phase reactants and
promotes growth and stimulation of RBCs
QUESTION>Cytokine TNF function - ANSWER~Causes fever, increases synthesis of proinflammatory
proteins by liver, causes muscle wasting, induces thrombosis
QUESTION>Cytokine growth factor function - ANSWER~Promotes production and maturation of
neutrophils
