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Exam (elaborations)

BIOS 4400 EXAM 2 WITH 100% VERIFIED SOLUTIONS!!

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BIOS 4400 EXAM 2 WITH 100% VERIFIED SOLUTIONS!!...

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BIOS 4400
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February 18, 2025
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2024/2025
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BIOS 4400 EXAM 2 WITH 100% VERIFIED SOLUTIONS!!



thalamus is located in ... - ANSWER diencephalon, near the center of the brain

- forms the dorsolateral walls of 3rd ventricle



function of thalamus - ANSWER relays and processes

sensory signals --> brain --> motor signals



thalami are connected across ..., via ... - ANSWER 3rd ventricle, inter thalamic
adhesion

- this adhesion only exists in 70% of humans



BG is composed of ... - ANSWER caudate nucleus (C), globus pallidus (GP), putamen
(Pu)



... separates medial and lateral nuclei - ANSWER internal medullary lamina



... separates thalamus from its reticular nucleus and internal capsule - ANSWER
external medullary lamina



... separates thalamus from BG & consists of thalamocortical and corticothalamic fibers
- ANSWER internal capsule



AN function - ANSWER memory and emotion



DM function - ANSWER motivation, drive, emotion - sensory integration for abstract
thinking and goal-directed behavior, may play a role in personality

,VA function - ANSWER initiation and planning of movement



VL function - ANSWER modulation and coordination of movement



VPM function - ANSWER somatosensation of head



VPL function - ANSWER somatosensation of body (touch, pain, temp, proprioception)



AN link ... with ... system - ANSWER thalamus, limbic

- papez circuit (emotion circuit involving hippo, thalamus, cingulate gyrus)



AN pathway - ANSWER hypothalamus (maxillary bodies) & hippocampus --> AN <-->
cingulate gyrus & limbic areas



papez circuit

- what is it associated with?

- give pathway - ANSWER emotional processing, memory - spatial and episodic



closed loop

entorhinal cortex --> hippocampus --> mammillary bodies --> AN --> cingulate cortex -->
entorhinal cortex



how the circuit functions in simplified manner (per presenter notes on ppt)

1. hippocampus projects to mammillary bodies via fornix

2. mammillary bodies connect to AN via mammillothalamic tract

3. AN project to cingulate gyrus

4. cingulate gyrus sends projections back to the hippocampus via the entorhinal cortex,
closing the loop

,DM pathway - ANSWER temporal lobe, amygdala, hypothalamus --> DM <--> PFC and
olfactory cortex



VA pathway - ANSWER BG --> VA <--> premotor cortex (area 6)



VL pathway - ANSWER BG and cerebellum --> VL <--> motor cortex (area 4)



VPL pathway - ANSWER lateral spinothalamic and medial lemnisci --> VPL <--> primary
somatosensory cortex (areas 1, 2, 3)



pain temperature, touch, pressure, vibration, position, movement from contralateral
trunk and limbs



VPM pathway - ANSWER ventral trigeminal tract (CN V) --> VPM <--> primary
somatosensory cortex (areas 1, 2, 3)



sensory info from head, face, oral cavity



DBS targets ... thalamic nucleus - ANSWER VIM (ventral intermediate)

- between VA and VL



DBS is used to treat ... - ANSWER essential tremor, PD, psychiatric disorders



Mid (median) function - ANSWER very complex and poorly understood fxn

- pain, emotion, addiction



Mid (median) pathway - ANSWER Mid <--> PFC and limbic system

, IL pathway - ANSWER premotor and sensory cortex --> IL --> motor cortex and BG



CM pathway - ANSWER CM <--> diffusely to cortex, BG (esp. GP), RAS
(neuromodulation, arousal, consciousness)



pulvinar function - ANSWER higher-order visual function

- largest nuclear group of thalamus

- well developed in primates



pulvinar pathway - ANSWER SC, IC, MGB, LGB --> Pul <--> visual association cortex



inferior pulvinar is connected to the ... and ... visual fields - ANSWER dorsal (parietal -
spatial processing, action)

ventral (temporal - object recognition, memory)



superior pulvinar has connections to ..., ..., ..., and ... corticies - ANSWER PFC, frontal,
parietal, and temporal



lateral pulvinar has connections to the ... cortex and retinotopic representation of the ...
visual hemifield - ANSWER visual, contralateral



L visual field projects to R visual cortex



MGB function - ANSWER relay for auditory pathway



MGB pathway - ANSWER brachium of IC --> MGB of thalamus --> ipsilateral primary
auditory cortex (areas 41 & 42)



sound in R ear --> IC --> L thalamus --> L auditory cortex

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