Pharm Tox Exam 3 UPDATED Exam
Questions and CORRECT Answers
least abundant of all immunoglobulins along with shortest serum half life - CORRECT
ANSWER - IgE
several properties of allergens - CORRECT ANSWER - elicit T cell response, proteolytic
activity, favor activation of IL4, low molecular weight, soluble, stable and survive dehydrated
form
3 types of drugs classified as bronchodilators - CORRECT ANSWER - beta 2 adrenergic
agonists, theophylline, anticholinergic agents
bronchodilator of choice - CORRECT ANSWER - inhaled beta 2 adrenergic agonsits
bronchodilator of choice for treating acute severe asthma; convenient and elicit fast response -
CORRECT ANSWER - short acting beta 2
preferred therapy for patients with persistent asthma - CORRECT ANSWER -
combination inhalers (long acting beta 2 + corticosteroid)
first line therapy for all but the mildest asthma b/c most effective at limiting asthma and has
minimal systemic effects - CORRECT ANSWER - inhaled corticosteroids
anti-asthma drug that inhibits PDE4; inexpensive; only slightly soluble in water; important to
measure blood levels of this drug b/c narrow therapeutic window - CORRECT ANSWER -
theophylline
drug class of theophylline - CORRECT ANSWER - methylxanthine
,drug of choice of COPD pts - CORRECT ANSWER - antimuscarinic agents
Jimson weed contains ________ and was/is used as a bronchodilator - CORRECT
ANSWER - atropine
atropine derivative anti-muscarinic agent used as a bronchodilator - CORRECT
ANSWER - ipratropium
mast cell stabilizers that act on sensory nerves; inhibit antigen and exercise-induced asthma -
CORRECT ANSWER - cromolyn; nedocromil
5-lipoxygenase inhibitor used for asthma - CORRECT ANSWER - zileuton
LTD4 receptor antagonist used for asthma - CORRECT ANSWER - zafirlukast;
montelukast
drug used for anti-IgE therapy - CORRECT ANSWER - omalizumab
Glaucoma is an age-related disease that:
A. is detected early due to central vision loss
B. is cured by aq suppression agents targeting autonomic receptors
C. is the #1 cause of reversible blindness in African Americans
D. is usually associated with elevated eye pressure and ganglion cell loss - CORRECT
ANSWER -D
Age-related macular degeneration can turn "wet" if angiogenesis occurs under the retina leading
to profound central vision loss; there are many antiVEGF products on the market for intra-vitreal
injection; which product is "off-label" per FDA guidelines?
A. Macugen
B. Eyelea
, C. Avastin
D. Lucentis - CORRECT ANSWER -C
Retrobulbar anesthesia has many surgical advantages EXCEPT:
A. diminishes vision temporarily
B. creates temporary recti muscle paralysis
C. inhibits pupil dilation
D. creates ocular and orbital anesthesia - CORRECT ANSWER -C
compression of the 3rd cranial nerve by an aneurysm can do the following, EXCEPT:
A. lead to an outward turning of the eye and double vision
B. limit upward gaze
C. cause a droopy upper eyelid and be associated with headaches
D. limit outward gaze - CORRECT ANSWER -D
glaucoma therapy traditionally targeted autonomic receptors in the ciliary body. A new
combination medicine, Combigan, has allowed better suppression of aq formation in one drop by
both:
A. stimulating alpha adrenergic receptors and blocking beta adrenergic receptors
B. stimulating alpha-adrenergic and beta-adrenergic receptors
C. increasing uveoscleral outflow
D. blocking beta adrenergic receptors and stimulating carbonic anhydrase II - CORRECT
ANSWER - A (repeated question)
a lung apex tumor can compress and damage the second order neuron in the sympathetic chain to
the pupil (Horners syndrome). In this scenario, application of 1% hydroxyamphetamine to the
ocular surface would result in:
A. no dilation of the pupil
B. pupil dilation
C. restoration of vision in that eye only
Questions and CORRECT Answers
least abundant of all immunoglobulins along with shortest serum half life - CORRECT
ANSWER - IgE
several properties of allergens - CORRECT ANSWER - elicit T cell response, proteolytic
activity, favor activation of IL4, low molecular weight, soluble, stable and survive dehydrated
form
3 types of drugs classified as bronchodilators - CORRECT ANSWER - beta 2 adrenergic
agonists, theophylline, anticholinergic agents
bronchodilator of choice - CORRECT ANSWER - inhaled beta 2 adrenergic agonsits
bronchodilator of choice for treating acute severe asthma; convenient and elicit fast response -
CORRECT ANSWER - short acting beta 2
preferred therapy for patients with persistent asthma - CORRECT ANSWER -
combination inhalers (long acting beta 2 + corticosteroid)
first line therapy for all but the mildest asthma b/c most effective at limiting asthma and has
minimal systemic effects - CORRECT ANSWER - inhaled corticosteroids
anti-asthma drug that inhibits PDE4; inexpensive; only slightly soluble in water; important to
measure blood levels of this drug b/c narrow therapeutic window - CORRECT ANSWER -
theophylline
drug class of theophylline - CORRECT ANSWER - methylxanthine
,drug of choice of COPD pts - CORRECT ANSWER - antimuscarinic agents
Jimson weed contains ________ and was/is used as a bronchodilator - CORRECT
ANSWER - atropine
atropine derivative anti-muscarinic agent used as a bronchodilator - CORRECT
ANSWER - ipratropium
mast cell stabilizers that act on sensory nerves; inhibit antigen and exercise-induced asthma -
CORRECT ANSWER - cromolyn; nedocromil
5-lipoxygenase inhibitor used for asthma - CORRECT ANSWER - zileuton
LTD4 receptor antagonist used for asthma - CORRECT ANSWER - zafirlukast;
montelukast
drug used for anti-IgE therapy - CORRECT ANSWER - omalizumab
Glaucoma is an age-related disease that:
A. is detected early due to central vision loss
B. is cured by aq suppression agents targeting autonomic receptors
C. is the #1 cause of reversible blindness in African Americans
D. is usually associated with elevated eye pressure and ganglion cell loss - CORRECT
ANSWER -D
Age-related macular degeneration can turn "wet" if angiogenesis occurs under the retina leading
to profound central vision loss; there are many antiVEGF products on the market for intra-vitreal
injection; which product is "off-label" per FDA guidelines?
A. Macugen
B. Eyelea
, C. Avastin
D. Lucentis - CORRECT ANSWER -C
Retrobulbar anesthesia has many surgical advantages EXCEPT:
A. diminishes vision temporarily
B. creates temporary recti muscle paralysis
C. inhibits pupil dilation
D. creates ocular and orbital anesthesia - CORRECT ANSWER -C
compression of the 3rd cranial nerve by an aneurysm can do the following, EXCEPT:
A. lead to an outward turning of the eye and double vision
B. limit upward gaze
C. cause a droopy upper eyelid and be associated with headaches
D. limit outward gaze - CORRECT ANSWER -D
glaucoma therapy traditionally targeted autonomic receptors in the ciliary body. A new
combination medicine, Combigan, has allowed better suppression of aq formation in one drop by
both:
A. stimulating alpha adrenergic receptors and blocking beta adrenergic receptors
B. stimulating alpha-adrenergic and beta-adrenergic receptors
C. increasing uveoscleral outflow
D. blocking beta adrenergic receptors and stimulating carbonic anhydrase II - CORRECT
ANSWER - A (repeated question)
a lung apex tumor can compress and damage the second order neuron in the sympathetic chain to
the pupil (Horners syndrome). In this scenario, application of 1% hydroxyamphetamine to the
ocular surface would result in:
A. no dilation of the pupil
B. pupil dilation
C. restoration of vision in that eye only
