m m
MODERN BLOOD BAN m m
KING & TRANSFUSION
m m m
PRACTICES 6TH EDITIO m m
N DENISE M. HARMENI
m m m
NG
,TEST BANK FOR
m m
MODERN BLOOD BANKING
m m m
& TRANSFUSION PRACTICES
m m
6TH EDITION
m
DENISE M. HARMENING
m m
, Chapter m1 mRBCsmandmPlateletmPreservation: mHistoricalmPerspectives mandmCurrentmTrends
MultiplemChoice
Identifymthemchoicemthatmbestmcompletesmthemstatementmormanswersmthemquestion.
1. Which mmetabolic mpathway mismresponsible mformgeneratingm90% mof mthemATPmformthemRBC?
a. Pentose mphosphate mshunt c. Glycolysis
b. Luebering-Rapoportmshunt d.m m Methemoglobin mreductase
2. Amunitmof mbloodmwasmreturnedmtomthemblood mbankmbeforemitmwasmspiked.mApparently mthempatient’smIVmfailed.
mThe munitmofmblood mwasmoutsidemthembloodmbank mform35 mminutes. mWhichmofmthe mstatements mbelow mismmostm
accurate?
a. Themunitmof mblood mshould mbemdiscarded mimmediately.
b. Themunitmof mblood mcan mbemreturned mto minventory.
c. Themunitmof mblood mmustmbemtransfused mwithin m4 mhoursmormbemdiscarded matmthemend mof mthatmtime.
d. Themunitmof mblood mmustmbemtransfused mwith m24 mhours.
3. Whatmismthemaverage mdiametermof mamplatelet?
a. 5 mto m10 mµm c. 1 mto m2 mµm
b. 2 mto m4 mµm d.m m 4 mto m6 mµm
4. In mthemnormalmhemoglobin-
oxygen mdissociationmcurve,mwhatmpercentagemofmoxygenmismreleased mtomthemtissuesmwhen mPO2maveragesm40
mmm mHg?
a. 75% c. 100%
b. 25% d.m m 50%
5. Whatmfactorsmaremknown mto minfluence mplateletmmetabolism mand mfunction?
a. Storage mtemperature c. Plateletmcount
b. InitialmpH d.m m Allmof mthemabove
6. Which mofmthemfollowingmred mbloodmcellmmorphologiesmmaymbempresentmonmthemperipheralmbloodmsmearmasmamr
esultmof mlossmof mRBCmmembrane?
a. Spherocytes c. Burrmcells
b. Targetmcells d.m m Schistocytes
7. Whatmdoesmthemtermmautologousmtransfusion mrefermto?
a. Amparentmdonatingmblood mformhismormhermchild
b. An mindividualmdonatingmblood mformamfriend
c. An mindividualmdonatingmblood mformamrelative
d. An mindividualmdonatingmblood mformhismormhermown mtransfusion
8. Whatmismthemprimary mfunction mof mhemoglobin?
a. Iron mmetabolism c. Oxygen mtransport
b. Porphyrin msynthesis d.m m Signalmtransduction
9. Allmof mthemfollowingmareasmof mred mblood mcellmbiology maremcrucialmformnormalmerythrocyte msurvivalm except:
a. Cellularmmetabolism. c. Sitemof mthemABOmantigen mattachment.
b. RBCmmembrane. d.m m Hemoglobin mstructure.
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, m 10.m m Whatmismthemcorrectmbiochemicalmcomposition mof mthemRBCmmembrane?
a. 52% mprotein,m40% mlipid,m8% mcarbohydrate
b. 40% mprotein,m8% mlipid,m52% mcarbohydrate
c. 8% mprotein,m52% mlipid,m40% mcarbohydrate
d. 8% mlipid,m40% mcarbohydrate, m52% mprotein
m 11.m m Allmof mthemfollowingmbiochemicalmchangesmaremassociatedmwithmlossmofmred mbloodmcellmviability muponmstorage
except:
a. Decreased mpH. c. Increased mATPmlevel.
b. Lossmof mred mblood mcellmfunction. d.m m Decreased mglucose mconsumption.
m 12.m m Which mred mblood mcellmpreservative mhasmamstoragemtimemof m35 mdays?
a. ACD c. AS-1
b. CPDA-1 d.m m CPD
m 13.m m ThemRBCmmembrane mismrelatively mpermeable mto mallmof mthemfollowingm except:
a. Chloride. c. Bicarbonate.
b. Sodium. d.m m Water.
m 14.m Whatmpercentagemofmplateletsmismsequestered minmthemspleen masmfunctionalmreservemaftermbeingmreleasedmfrom
mthe mbone mmarrow?
a. 30% c. 10%
b. 50% d.m m 25%
m 15.m Whatmismthemmajormbiochemicalmconsideration min mplateletmstorage?
a. Glucose mmetabolism c. Production mof mcarbon mdioxide
b. Oxygen msupply d.m m Regulation mof mpH
m 16.m Whatmwould mthemhemoglobin-
oxygen mdissociation mcurvemdepictmin mampatientmexhibitingmclinicalmsignsmof malkalosis?
a. Normal c. Shiftmto mthemright
b. Shiftmto mthemleft d.m m Nonemof mthemabove
m 17.m m Namemthemmain mlipid mcomponentsmof mamred mblood mcellmmembrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d.m m Glycophorin mA
m 18.m m ThemABOmblood mgroupsmweremdiscovered min m1901 mby mwhom?
a. CharlesmDrew c. Loutitmand mMollison
b. KarlmLandsteiner d.m m Edward mLindeman
m 19.m Amstandingmordermofmplateletsmwasmshipped mtomyourmfacilitymbymyourmsupplier.mItmwasminadvertently mleftminmt
hemcornermofmthemdepartmentmuntilmdiscoveredm36mhoursmlater.mWhatmwouldmthemappropriatemaction mbemformth
emblood mbanker?
a. If mthemtemperature min mthembox mwasm22 m+/-
m2°Cmand mthe mplateletmswirlmseemedmOK,mitmwouldmbemOKmto macceptmthe munitminto minventor
y.
b. Themplateletsmhavemfallen moutside mthemsupplier’smquality massurance.mThemunitmshould mbe
discardedmbecausemthempHmhasmprobably mdropped mtoomlowmandmplateletmactivation mhasmbeen mcom
promised.
c. If mthemtemperature mwasm1°Cmto m6°Cmand mthemplateletmswirlmseemed mOK,mitmwould mbemOKmto
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