Ciulla: Hematology UPDATED ACTUAL Questions and CORRECT Answers

Ciulla: Hematology UPDATED ACTUAL
Questions and CORRECT Answers
1. What is the first type of cell produced by the developing embryo?


A. Erythrocyte
B. Granulocyte
C. Lymphocyte

D. Thrombocyte - CORRECT ANSWER - A. Erythrocyte


2. What percentage of tissue located in the bone marrow cavities of adults is fat?


A. 10%
B. 25%
C. 50%

D. 75% - CORRECT ANSWER - C. 50%


3. Which of the following is not characteristic of pluripotent hematopoietic stem cells?


A. Possess self-renewal ability
B. Produce progenitor cells committed to a single cell lineage
C. Express the stem cell marker CD 13

D. Are morphologically unrecognizable - CORRECT ANSWER - C. Express the stem cell
marker CD 13


4. In an adult, what are the two best areas for obtaining active bone marrow by aspiration?


A. Vertebra,tibia

,B. Sternum,vertebra
C. Anterior iliac crest, tibia

D. Posterior iliac crest, sternum - CORRECT ANSWER - D. Posterior iliac crest, sternum


5. What is the normal ratio of myeloid to erythroid precursors in bone marrow (M:E ratio)?


A. 1:1
B. 1:3
C. 4:1

D. 8:1 - CORRECT ANSWER - C. 4:1


6. Which of the following does not accurately describe hematopoietic growth factors?


A. Bind to target cell receptors to express
activity
B. Action of majority is lineage restricted
C. May promote or suppress cell death
D. Can stimulate or inhibit cell

proliferation - CORRECT ANSWER - B. Action of majority is lineage restricted


7. In the third month of gestation, what is the primary site of hematopoiesis?


A. Liver
B. Marrow of long bones
C. Spleen

D. Yolksac - CORRECT ANSWER - A. Liver

,8. The mechanism that relays information about tissue oxygen levels to erythropoietin-producing
sites is located in the


A. Brain
B. Kidney
C. Liver

D. Spleen - CORRECT ANSWER - B. Kidney


9. Antigen-independent lymphopoiesis occurs in primary lymphoid tissue located in the


A. Liver and kidney
B. Spleen and lymph nodes
C. Peyer's patches and spleen

D. Thymus and bone marrow - CORRECT ANSWER - D. Thymus and bone marrow


10. Programmed cell death is called


A. Necrosis
B. Apoptosis
C. Cellular senescence

D. Terminal differentiation - CORRECT ANSWER - B. Apoptosis


11. In what area of the bone marrow does hematopoiesis take place?


A. Cords
B. Endosteum
C. Endothelium

D. Sinuses - CORRECT ANSWER - A. Cords

, 12. Bone marrow cellularity refers to the ratio of


A. Red cell precursors to white cell precursors
B. Hematopoietic tissue to adipose tissue
C. Granulocytic cells to erythrocytic cells
D. Extra vascular tissue to intravascular

tissue - CORRECT ANSWER - B. Hematopoietic tissue to adipose tissue


13. Interleukins and colony stimulating factors are cytokines produced by


A. B lymphocytes and erythrocytes
B. Erythrocytes and thrombocytes
C. Monocytes and T lymphocytes

D. Neutrophils and monocytes - CORRECT ANSWER - C. Monocytes and T lymphocytes


14. What is the approximate total blood volume in an adult?


A. 1 L
B. 2 L
C. 6 L

D. 12 L - CORRECT ANSWER - C. 6 L


15. The myeloid progenitor cell can produce cells committed to


A. Granulocytic, erythrocytic, monocytic,
or megakaryocytic lineages
B. Granulocytic, monocytic, lympho-