Questions and CORRECT Answers
Following ultracentrifugation of plasma, which fraction correlates with pre β lipoprotein?
A. Very low density lipoprotein (VLDL)
B. Low density lipoprotein (LDL)
C. High density lipoprotein (HDL)
D. Chylomicrons - CORRECT ANSWER -A
Select the lipoprotein fraction that carries most the endogenous triglycerides
A. VLDL
B. LDL
C. HDL
D. Chylomicrons - CORRECT ANSWER -A
The protein composition of HDL is what percentage by weight?
A. Less than 2%
B. 25%
C. 50%
D. 90% - CORRECT ANSWER -C
Which apoprotein is inversely related to risk of coronary heart disease?
A. Apoprotein A-I
B. Apoprotein B-100
C. Apoprotein C-II
D. Apoprotein E4 - CORRECT ANSWER -A
Which lipoprotein accumulates in familiar β dyslipoproteinemia?
, A. Chylomicrons
B. VLDL
C. IDL
D. HDL - CORRECT ANSWER -C
Which of the following mechanisms accounts for the elevated plasma level of β liproproteins
seen in familial hypercholesterolemia?
A. Hyperinsulinemia
B. ApoB-100 receptor defect
C. ApoC-II activated lipase deficiency
D. ApoE3 deficiency - CORRECT ANSWER -B
Which enzyme deficiency is most commonly associated with familial hypertriglyceridemia
associated with fasting plasma cholomicrons?
A. β- Glucocerebrosidase deficiency
B. Post heparin activated lipoprotein lipase deficiency
C. Apo B deficiency
D. Apo C-III deficiency - CORRECT ANSWER -B
Which of the following conditions is most consistently associated with secondary
hypercholesterolemia?
A. Hypothyroidism
B. Pancreatitis
C. Oral contraceptive therapy
D. Diabetes mellitus - CORRECT ANSWER -A
Which of the following is associated with Tangier disease?
A. Apoprotein C-II deficiency
B. Homozygous apo B-100 deficiency