ASCP - Immunology Exam Questions Solved 100% Latest Update 2025 Already Passed
The properties of an antibody class are defined by the: - Answers Fc end of the molecule
Which subset of effector lymphocytes is predominantly responsible for regulation of antibody
production? - Answers TH12
The primary purpose of neutrophil granules is to: - Answers Provide microbicidal action
T lymphocytes are characterized by all of the following functions EXCEPT which? - Answers synthesize
antibody
The immunoglobulin molecule is made up of both heavy and light chains - the light chains can be
comprised of which of the following? - Answers Kappa or lambada
All of the following are applications of real-time PCR, EXCEPT? - Answers Amplification of DNA for
northern blot
Diseases associated with a dysfunction of polymorphonuclear neutrophils (PMNs) include all of the
following with the exception of? - Answers Gaucher's disease
Which of the following is responsible for the humoral immune response: - Answers B-lymphocytes
Which of the following types of lymphocytes express CD4? - Answers Only T-helper cells
HLA antibodies are responsible for which of the following transfusion reactions? - Answers Transfusion
related acute lung injury (TRALI)
Identify a characteristic of an organ-non specific disorder that distinguishes it from an organ specific
disorfer - Answers Lesions cause by deposition of antigen-antibody inmmune complexes
What section of an immunoglobulin molecule is responsible for the differences between
immunoglobulin classes? - Answers Heavy chains
.Which of the following is responsible for causing transfusion associated graft-versus-host disease? -
Answers Lymphocytes
What is the most common early abnormality observed in the lymph nodes of AIDS patients? - Answers
Reactive lymphodenopathy
All of the following conditions are associated with a polyclonal (broadbased) increase in gamma
globulins except? - Answers Immunodeficiency
Which of the following statements is true regarding anti-nuclear antibodies? - Answers 95% of patients
with SLE tests positive for ANAs
What three hepatitis B virus (HBV) early markers are detectable in serum during the first two months
after infecyion? - Answers HBsAg, HBeAg, anti-HBc
, Which of the following is used to determine if a person has had a recent infection with Strep pyogenes?
- Answers Antistreptolysin O (ASO)
.All of the following would be considered a part of the body's cellular immune system EXCEPT? -
Answers Thrombocytes
.Which of the following is used as an indicator of inflammation? - Answers C-reactive Protein (CRP)
CD5 antigen is normally found on which of the following lymphocyte populations? - Answers Mature T
cells
.Examples of cytokines originating from activated T-cells include: - Answers IL2, IL3
What is the expected serological response in an immunocompetent patient who has been vaccinated for
hepatitis B? - Answers HBsAg (neg), Anti-HBc (neg), anti-HBs (pos)
A 2-month old infant presented with history of chronic diarrhea and failure to thrive. The child's mother
also reveal that the baby has suffere from trush - Answers severe combine immunodeficiency syndrome
For the diagnosis of Systemic Lupus Erythematosus (SLE) which of the following test principles provides
the highes specificity? - Answers ELISA
What is the process of monoclonal antibody production? - Answers Fusion of antibody specific
lymphocyte and myeloma cell
Which of the following antibody types is the predominant serum antibody seen in the secondary
immune response? - Answers IgM
In what trimester is there the greatest risk for the manifestation of complications in maternal rubella
infection - Answers First trimester
Skin and mucous membranes are important components of what part of the immune system? - Answers
Innate immunity
What is the purpose of the Total Complement Activity (CH50) assay? - Answers Measures classic or
terminal complement pathway
An indirect latex agglutination assay was used to test for C-reactive protein in a patient sample. The
result of the serial dilution are provided in the image. - Answers Positive 1:12
Which modified PCR technique or other method of amplification is used to detect Mycobacterium
tuberculosis? - Answers Transcription mediated Amplification
What part of an immunoglobulin (Ig) molecule exists as kappa or lambda chains? - Answers Light chains
.The characteristics of an acute phase protein include the following EXCEPT: - Answers Acute phase
protein are synthesized slowly in response to tissue injury
The properties of an antibody class are defined by the: - Answers Fc end of the molecule
Which subset of effector lymphocytes is predominantly responsible for regulation of antibody
production? - Answers TH12
The primary purpose of neutrophil granules is to: - Answers Provide microbicidal action
T lymphocytes are characterized by all of the following functions EXCEPT which? - Answers synthesize
antibody
The immunoglobulin molecule is made up of both heavy and light chains - the light chains can be
comprised of which of the following? - Answers Kappa or lambada
All of the following are applications of real-time PCR, EXCEPT? - Answers Amplification of DNA for
northern blot
Diseases associated with a dysfunction of polymorphonuclear neutrophils (PMNs) include all of the
following with the exception of? - Answers Gaucher's disease
Which of the following is responsible for the humoral immune response: - Answers B-lymphocytes
Which of the following types of lymphocytes express CD4? - Answers Only T-helper cells
HLA antibodies are responsible for which of the following transfusion reactions? - Answers Transfusion
related acute lung injury (TRALI)
Identify a characteristic of an organ-non specific disorder that distinguishes it from an organ specific
disorfer - Answers Lesions cause by deposition of antigen-antibody inmmune complexes
What section of an immunoglobulin molecule is responsible for the differences between
immunoglobulin classes? - Answers Heavy chains
.Which of the following is responsible for causing transfusion associated graft-versus-host disease? -
Answers Lymphocytes
What is the most common early abnormality observed in the lymph nodes of AIDS patients? - Answers
Reactive lymphodenopathy
All of the following conditions are associated with a polyclonal (broadbased) increase in gamma
globulins except? - Answers Immunodeficiency
Which of the following statements is true regarding anti-nuclear antibodies? - Answers 95% of patients
with SLE tests positive for ANAs
What three hepatitis B virus (HBV) early markers are detectable in serum during the first two months
after infecyion? - Answers HBsAg, HBeAg, anti-HBc
, Which of the following is used to determine if a person has had a recent infection with Strep pyogenes?
- Answers Antistreptolysin O (ASO)
.All of the following would be considered a part of the body's cellular immune system EXCEPT? -
Answers Thrombocytes
.Which of the following is used as an indicator of inflammation? - Answers C-reactive Protein (CRP)
CD5 antigen is normally found on which of the following lymphocyte populations? - Answers Mature T
cells
.Examples of cytokines originating from activated T-cells include: - Answers IL2, IL3
What is the expected serological response in an immunocompetent patient who has been vaccinated for
hepatitis B? - Answers HBsAg (neg), Anti-HBc (neg), anti-HBs (pos)
A 2-month old infant presented with history of chronic diarrhea and failure to thrive. The child's mother
also reveal that the baby has suffere from trush - Answers severe combine immunodeficiency syndrome
For the diagnosis of Systemic Lupus Erythematosus (SLE) which of the following test principles provides
the highes specificity? - Answers ELISA
What is the process of monoclonal antibody production? - Answers Fusion of antibody specific
lymphocyte and myeloma cell
Which of the following antibody types is the predominant serum antibody seen in the secondary
immune response? - Answers IgM
In what trimester is there the greatest risk for the manifestation of complications in maternal rubella
infection - Answers First trimester
Skin and mucous membranes are important components of what part of the immune system? - Answers
Innate immunity
What is the purpose of the Total Complement Activity (CH50) assay? - Answers Measures classic or
terminal complement pathway
An indirect latex agglutination assay was used to test for C-reactive protein in a patient sample. The
result of the serial dilution are provided in the image. - Answers Positive 1:12
Which modified PCR technique or other method of amplification is used to detect Mycobacterium
tuberculosis? - Answers Transcription mediated Amplification
What part of an immunoglobulin (Ig) molecule exists as kappa or lambda chains? - Answers Light chains
.The characteristics of an acute phase protein include the following EXCEPT: - Answers Acute phase
protein are synthesized slowly in response to tissue injury
