Immunology & Serology Final || A Verified A+ Pass.
First line of defense against infection correct answers Unbroken skin and mucosal membranes
3 immunologically functional groups of WBC correct answers 1. Granulocytes
2. Lymphocytes
3. Monocytes
5 types of luekocytes correct answers 1. Neutrophils
2. Eosinophils
3. Basophils
4. Monocytes
5. Mast Cell
Antigen definition correct answers Substance on RBC that reacts with antibody or sensitized T
cell but may not be able to evoke an immune response
5 classes of immunoglobulins (antibodies) correct answers 1. IgG
2. IgM
3. IgE
4. IgA
5. IgD
Immunoglobulin most efficient at binding complement, can cross placenta, and has the largest
hinge region. correct answers IgG
Immunoglobulin with 10 functional binding sites, able to fix complement, first to appear, and is
the largest. correct answers IgM
Immunoglobulin that plays a protective role by triggering acute inflammatory reaction correct
answers IgE
Immunoglobulin that plays a role in B cell activation and is the second to appear correct answers
IgD
Immunoglobulin that contains a secretory component and patrols mucosal surfaces correct
answers IgA
Basic Antibody Structure correct answers
Direct Bacterial Agglutination correct answers Known bacterial antigens test against patient's
unknown antibody
Coagglutination correct answers Using bacterial as inert particles to which antibody is attached
, Latex Agglutination correct answers Latex particles sensitized with antigen bind to patient's
antibodies
Hemagglutination correct answers Agglutination involving RBC
Liposome Mediated Agglutination correct answers Liposomes from closed vesicles under
appropriate conditions where antigen/antibodies molecules incorporate onto membrane and are
available for binding counterpart.
PCR correct answers Amplifying tiny quantities of nucleic acid
Southern Blot correct answers Analysis of DNA fragments
Northern Blot correct answers Analysis of RNA fragments
DNA Chip Technology correct answers Examine DNA and allows thousand of biological
reactions to be performed at once
Western Blot correct answers Protein based antibody detection
What test detects a wide range of antibodies and is POS in 95% of patients with SLE correct
answers Antinuclear Antibody Testing (ANA)
Is RF (rheumatoid factor) specific for Rheumatoid Arthritis (RA)? correct answers No. Only
75% of RA patients are POS and some healthy individuals are POS for RF
3 protective mechanisms against bacteria correct answers 1. Production of fever
2. Phagocytosis
3. Activation of complement
Characteristics of Streptococcal M proteins correct answers 1. Chief virulence factor of group A
strep
2. Provokes immune response
3. Limits phagocytosis of the organism
ASO titer NEG with hemolysis in all tubes.
Streptoenzyme test POS.
Controls okay. What do you conclude about test? correct answers Patient has antibody to a
streptococcal exoenzyme other than streptolysin O
In what disease do antibodies to group A streptococci cross-react with heart tissue? correct
answers Acute Rheumatic Fever
What indicates the presence of anti-DNase B activity in serum? correct answers Lack of change
in the color indicator
First line of defense against infection correct answers Unbroken skin and mucosal membranes
3 immunologically functional groups of WBC correct answers 1. Granulocytes
2. Lymphocytes
3. Monocytes
5 types of luekocytes correct answers 1. Neutrophils
2. Eosinophils
3. Basophils
4. Monocytes
5. Mast Cell
Antigen definition correct answers Substance on RBC that reacts with antibody or sensitized T
cell but may not be able to evoke an immune response
5 classes of immunoglobulins (antibodies) correct answers 1. IgG
2. IgM
3. IgE
4. IgA
5. IgD
Immunoglobulin most efficient at binding complement, can cross placenta, and has the largest
hinge region. correct answers IgG
Immunoglobulin with 10 functional binding sites, able to fix complement, first to appear, and is
the largest. correct answers IgM
Immunoglobulin that plays a protective role by triggering acute inflammatory reaction correct
answers IgE
Immunoglobulin that plays a role in B cell activation and is the second to appear correct answers
IgD
Immunoglobulin that contains a secretory component and patrols mucosal surfaces correct
answers IgA
Basic Antibody Structure correct answers
Direct Bacterial Agglutination correct answers Known bacterial antigens test against patient's
unknown antibody
Coagglutination correct answers Using bacterial as inert particles to which antibody is attached
, Latex Agglutination correct answers Latex particles sensitized with antigen bind to patient's
antibodies
Hemagglutination correct answers Agglutination involving RBC
Liposome Mediated Agglutination correct answers Liposomes from closed vesicles under
appropriate conditions where antigen/antibodies molecules incorporate onto membrane and are
available for binding counterpart.
PCR correct answers Amplifying tiny quantities of nucleic acid
Southern Blot correct answers Analysis of DNA fragments
Northern Blot correct answers Analysis of RNA fragments
DNA Chip Technology correct answers Examine DNA and allows thousand of biological
reactions to be performed at once
Western Blot correct answers Protein based antibody detection
What test detects a wide range of antibodies and is POS in 95% of patients with SLE correct
answers Antinuclear Antibody Testing (ANA)
Is RF (rheumatoid factor) specific for Rheumatoid Arthritis (RA)? correct answers No. Only
75% of RA patients are POS and some healthy individuals are POS for RF
3 protective mechanisms against bacteria correct answers 1. Production of fever
2. Phagocytosis
3. Activation of complement
Characteristics of Streptococcal M proteins correct answers 1. Chief virulence factor of group A
strep
2. Provokes immune response
3. Limits phagocytosis of the organism
ASO titer NEG with hemolysis in all tubes.
Streptoenzyme test POS.
Controls okay. What do you conclude about test? correct answers Patient has antibody to a
streptococcal exoenzyme other than streptolysin O
In what disease do antibodies to group A streptococci cross-react with heart tissue? correct
answers Acute Rheumatic Fever
What indicates the presence of anti-DNase B activity in serum? correct answers Lack of change
in the color indicator
