ABRAMS'66CLINICAL66DRUG66THERAPY:66RATIONALES66FOR66NURSING66PRACTICE
,ABRAMS'66CLINICAL66DRUG66THERAPY:66RATIONALES66FOR66NURSING66PRACTICE
,ABRAMS'66CLINICAL66DRUG66THERAPY:66RATIONALES66FOR66NURSING66PRACTICE
, ABRAMS'66CLINICAL66DRUG66THERAPY:66RATIONALES66FOR66NURSING66PRACTICE
Chapter661,66The66Foundation66of66Pharmacology:66Quality66and66Safety
1. A66woman66diagnosed66with66obsessive–
compulsive66disorder66has66been66prescribed66oral66paroxetine66hydrochloride.66W
hat66is66the66expected66effect66for66this66prescription?
A. Curative66effect66on66symptoms
B. Systemic66effect66on66symptoms
C. Local66effect66on66symptoms
D. Parenteral66effect66on66symptoms
ANS:6 6 B
Rationale:66Drugs66that66produce66systemic66effects66are66taken66into66the66body,66circulate
d66through66the66bloodstream66to66their66sites66of66action66in66various66body66tissues,66and6
6eventually66eliminated66from66the66body.66Curative66agents66are66given66to66cure66a66disea
se66process.66In66this66case,66paroxetine66hydrochloride66will66control66the66symptoms66but
66not66cure66the66disorder.66Drugs66with66local66effects,66such66as66sunscreen66and66local66an
esthetics,66act66mainly66at66the66site66of66application.66Paroxetine66hydrochloride66is66not66
administered66parenterally.66Parenteral66agents66are66administered66subcutaneously,66intra
muscularly,66or66intravenously.
PTS: 1 REF: p.663,66Introduction OBJ: 1
NAT:6 6 Client66Needs:66Physiological66Integrity:66Pharmacological66and66Parenteral66T
herapies66TOP:
Chapter:661:66The66Foundation66of66Pharmacology:66Quality66and66Safety
KEY:6 6 Integrated66Process:66Nursing66Process
BLM:6 6 Cognitive66Level:66Understand NOT:6 6 Multiple66Choice
2. A66client66has66been66prescribed66an66antibiotic.66This66medication66is66a66naturally66occurring
substance66that66has66been66cheG
mRicA
alDlyEm
SoBdOifOieSd.TWhaOt66M
.C is66another66name66for66this66ty
pe66of66medication?
A. Synthetic66drug
B. Semisynthetic66drug
C. Biotechnology66drug
D. Prototype66drug
ANS:6 6 B
Rationale:66Semisynthetic66drugs66(e.g.,66many66antibiotics)66are66naturally66occurring66sub
stances66that66have66been66chemically66modified.66Synthetic66drugs66are66more66standardize
d66in66their66chemical66characteristics,66more66consistent66in66their66effects,66and66less66likely
66to66produce66allergic66reactions.66Biotechnology66drugs66involve66manipulating66DNA66a
nd66RNA66and66recombining66genes66into66hybrid66molecules66that66can66be66inserted66into6
6living66organisms.66Prototype66drugs66are66the66first66drug66of66a66particular66group66to66be
66developed.
PTS: 1 REF: p.663,66Drug66Sources OBJ: 1
NAT:6 6 Client66Needs:66Physiological66Integrity:66Pharmacological66and66Parenteral66T
herapies66TOP:
Chapter:661:66The66Foundation66of66Pharmacology:66Quality66and66Safety
KEY:6 6 Integrated66Process:66Nursing66Process
BLM:6 6 Cognitive66Level:66Understand NOT:6 6 Multiple66Choice
3. Which66classification66applies66to66morphine?
A. Central66nervous66system66depressant
ABRAMS'66CLINICAL66DRUG66THERAPY:66RATIONALES66FOR66NURSING66PRACTICE
,ABRAMS'66CLINICAL66DRUG66THERAPY:66RATIONALES66FOR66NURSING66PRACTICE
,ABRAMS'66CLINICAL66DRUG66THERAPY:66RATIONALES66FOR66NURSING66PRACTICE
, ABRAMS'66CLINICAL66DRUG66THERAPY:66RATIONALES66FOR66NURSING66PRACTICE
Chapter661,66The66Foundation66of66Pharmacology:66Quality66and66Safety
1. A66woman66diagnosed66with66obsessive–
compulsive66disorder66has66been66prescribed66oral66paroxetine66hydrochloride.66W
hat66is66the66expected66effect66for66this66prescription?
A. Curative66effect66on66symptoms
B. Systemic66effect66on66symptoms
C. Local66effect66on66symptoms
D. Parenteral66effect66on66symptoms
ANS:6 6 B
Rationale:66Drugs66that66produce66systemic66effects66are66taken66into66the66body,66circulate
d66through66the66bloodstream66to66their66sites66of66action66in66various66body66tissues,66and6
6eventually66eliminated66from66the66body.66Curative66agents66are66given66to66cure66a66disea
se66process.66In66this66case,66paroxetine66hydrochloride66will66control66the66symptoms66but
66not66cure66the66disorder.66Drugs66with66local66effects,66such66as66sunscreen66and66local66an
esthetics,66act66mainly66at66the66site66of66application.66Paroxetine66hydrochloride66is66not66
administered66parenterally.66Parenteral66agents66are66administered66subcutaneously,66intra
muscularly,66or66intravenously.
PTS: 1 REF: p.663,66Introduction OBJ: 1
NAT:6 6 Client66Needs:66Physiological66Integrity:66Pharmacological66and66Parenteral66T
herapies66TOP:
Chapter:661:66The66Foundation66of66Pharmacology:66Quality66and66Safety
KEY:6 6 Integrated66Process:66Nursing66Process
BLM:6 6 Cognitive66Level:66Understand NOT:6 6 Multiple66Choice
2. A66client66has66been66prescribed66an66antibiotic.66This66medication66is66a66naturally66occurring
substance66that66has66been66cheG
mRicA
alDlyEm
SoBdOifOieSd.TWhaOt66M
.C is66another66name66for66this66ty
pe66of66medication?
A. Synthetic66drug
B. Semisynthetic66drug
C. Biotechnology66drug
D. Prototype66drug
ANS:6 6 B
Rationale:66Semisynthetic66drugs66(e.g.,66many66antibiotics)66are66naturally66occurring66sub
stances66that66have66been66chemically66modified.66Synthetic66drugs66are66more66standardize
d66in66their66chemical66characteristics,66more66consistent66in66their66effects,66and66less66likely
66to66produce66allergic66reactions.66Biotechnology66drugs66involve66manipulating66DNA66a
nd66RNA66and66recombining66genes66into66hybrid66molecules66that66can66be66inserted66into6
6living66organisms.66Prototype66drugs66are66the66first66drug66of66a66particular66group66to66be
66developed.
PTS: 1 REF: p.663,66Drug66Sources OBJ: 1
NAT:6 6 Client66Needs:66Physiological66Integrity:66Pharmacological66and66Parenteral66T
herapies66TOP:
Chapter:661:66The66Foundation66of66Pharmacology:66Quality66and66Safety
KEY:6 6 Integrated66Process:66Nursing66Process
BLM:6 6 Cognitive66Level:66Understand NOT:6 6 Multiple66Choice
3. Which66classification66applies66to66morphine?
A. Central66nervous66system66depressant
ABRAMS'66CLINICAL66DRUG66THERAPY:66RATIONALES66FOR66NURSING66PRACTICE
