NR565 FINAL EXAM QUESTIONS WITH
CORRECT ANSWERS 2025
WhatRlabsRareRusedRtoRdiagnoseRthyroidRfunction?R-RCORRECTRANSWERR-1.RSerumRthyroid-
stimulatingRhormoneRtestR(TSH)
2.RSerumRthyroxineRtestR(TotalRorRFreeRT4)
3.RSerumRtriiodothyronineRtestR(TotalRorRFreeRT3)
s/sRhypothyroidismR-RCORRECTRANSWERR-
SignsRandRsymptomsRofRhypothyroidismRdependRonRdiseaseRseverity.RTheRfaceRisRpale,Rpuffy,RandRexpressi
onless;RskinRisRcoldRandRdry;RhairRisRbrittle;RhairRlossRoccurs;HeartRrateRandRtemperatureRareRlowered.RTheR
patientRmayRcomplainRofRlethargy,Rfatigue,RandRintoleranceRtoRcold.RMentationRmayRbeRimpaired.
s/sRhyperthyroidismR-RCORRECTRANSWERR-
Exophthalmos;RHeartbeatRisRrapidRandRstrong;RdysrhythmiasRandRanginaRmayRdevelop;Rnervousness;Rinso
mnia,RrapidRthoughtRflow;RrapidRspeech;RSkeletalRmusclesRmayRweakenRandRatrophy;RMetabolicRrateRisRrais
ed,RresultingRinRincreasedRheatRproduction,RincreasedRbodyRtemperature,RintoleranceRtoRheat,RandRskinRth
atRisRwarmRandRmoist.RAppetiteRisRincreased,RbutRweightRlossRmayRstillRoccur.
WhenRshouldRyouRre-checkRlabsRafterRinitiatingRLevothyroxine?R-RCORRECTRANSWERR-TSHR6-
8RweeksRafterRinitiationRorRdoseRchanges.
S/SRofRThyrotoxicRCrisisR(ThyroidRStorm)R-RCORRECTRANSWERR-
profoundRhyperthermiaR(105°FRorRevenRhigher),RsevereRtachycardia,Rrestlessness,Ragitation,RandRtremor.RU
nconsciousness,Rcoma,Rhypotension,RandRheartRfailureRmayRoccur
*ExcessiveRlevelsRofRthyroidRhormonesR(occursRafterRsurgeryRorRintercurrentRillnessR(e.g.Rsepsis)
TreatmentRofRthyroidRstormR-RCORRECTRANSWERR-*MEDICALREMERGENCY*R
1.HighRdosesRofRpotassiumRiodideRorRstrongRiodineRsolutionRareRgivenRtoRsuppressRthyroidRhormoneRreleas
e.R
2.MethimazoleRisRgivenRtoRsuppressRthyroidRhormoneRsynthesis.R3.ARβ-
blockerRisRgivenRtoRreduceRheartRrate.R
AdditionalRmeasuresRincludeRsedation,Rcooling,RandRgivingRglucocorticoidsRandRIVRfluids.
,WhatRcanRresultRfromRnotRtreatingRhypothyroidismRduringRpregnancy?R-RCORRECTRANSWERR-
permanentRneuropsychologicalRdeficitsRinRtheRchild
TreatmentRofRhyperthyroidismR-RCORRECTRANSWERR-1.RsurgicalRremovalRofRthyroidRtissue
2.RdestructionRofRthyroidRtissueRwithRradioactiveRiodineR(preferredRforRadults)
3.RantithyroidRdrugR(methimazoleRorRpropylthiouracil).R(preferredRforRyoungerRpatients)R
β-BlockersRsuppressRtachycardiaRbyRblockingRβ-receptorsRonRtheRheart.
NonradioactiveRiodineRinhibitsRsynthesisRandRreleaseRofRthyroidRhormones.
DrugsRthatRreduceRabsorptionRofRlevothyroxineR-RCORRECTRANSWERR-
HistamineR2R(H2)RreceptorRblockersR(e.g.,RcimetidineR[Tagamet])
ProtonRpumpRinhibitorsR(e.g.,RlansoprazoleR[Prevacid])
SucralfateR(Carafate)
CholestyramineR(Questran)
ColestipolR(Colestid)
Aluminum-containingRantacidsR(e.g.,RMaalox,RMylanta)
CalciumRsupplementsR(e.g.,RTums,ROs-Cal)
IronRsupplementsR(e.g.,RferrousRsulfate)
MagnesiumRsalts
OrlistatR(Xenical)
*administerR4RhoursRapartRfromRlevothyroxine*
FoodRinteractionsRwithRlevothyroxineR-RCORRECTRANSWERR-
FoodRdecreasesRabsorption.RShouldRbeRtakenRonRanRemptyRstomachR30-60RminutesRpriorRtoRbreakfast
DrugsRthatRaccelerateRlevothyroxineRmetabolismR-RCORRECTRANSWERR-phenytoinR(Dilantin)
carbamazepineR(Tegretol,RCarbatrol)
, rifampinR(Rifadin)
sertralineR(Zoloft)
phenobarbital.
*ToRmaintainRadequateRlevothyroxineRlevels,RpatientsRtakingRtheseRdrugsRmayRneedRtoRincreaseRtheirRlevo
thyroxineRdosage.
*DigoxinRandRInsulinRmayRhaveRmoreRrequirementsRwhenRtakingRlevothyroxine
WhichRlaboratoryRtestsRshouldRbeRcompletedRbeforeRprescribingRmethimazole?R-RCORRECTRANSWERR-
freeRtriiodothyronineR(T3)
freeRthyroxineR(T4)
LFTs
thyroid-stimulatingRhormoneR(TSH)
CBC
WhichRagentRisRtheRpreferredRtreatmentRoptionRforRthyroidRstorm?R-RCORRECTRANSWERR-
PTUR(propylthiouracil)
WhichRagentRisRtheRfirst-lineRtreatmentRforRhyperthyroidismRorRGrave'sRdisease?R-RCORRECTRANSWERR-
methimazole
HowRtoRconfirmRdiabetesRdiagnosisR-RCORRECTRANSWERR-FastingRplasmaRglucoseR≥126Rmg/dLa
Or
RandomRplasmaRglucoseR≥R200Rmg/dLRplusRsymptomsRofRdiabetesb
Or
OralRglucoseRtoleranceRtestR(OGTT):R2-hRplasmaRglucoseR≥200Rmg/dLc
or
HemoglobinRA1cR6.5%RorRhigherR(STANDARDRTEST)
CORRECT ANSWERS 2025
WhatRlabsRareRusedRtoRdiagnoseRthyroidRfunction?R-RCORRECTRANSWERR-1.RSerumRthyroid-
stimulatingRhormoneRtestR(TSH)
2.RSerumRthyroxineRtestR(TotalRorRFreeRT4)
3.RSerumRtriiodothyronineRtestR(TotalRorRFreeRT3)
s/sRhypothyroidismR-RCORRECTRANSWERR-
SignsRandRsymptomsRofRhypothyroidismRdependRonRdiseaseRseverity.RTheRfaceRisRpale,Rpuffy,RandRexpressi
onless;RskinRisRcoldRandRdry;RhairRisRbrittle;RhairRlossRoccurs;HeartRrateRandRtemperatureRareRlowered.RTheR
patientRmayRcomplainRofRlethargy,Rfatigue,RandRintoleranceRtoRcold.RMentationRmayRbeRimpaired.
s/sRhyperthyroidismR-RCORRECTRANSWERR-
Exophthalmos;RHeartbeatRisRrapidRandRstrong;RdysrhythmiasRandRanginaRmayRdevelop;Rnervousness;Rinso
mnia,RrapidRthoughtRflow;RrapidRspeech;RSkeletalRmusclesRmayRweakenRandRatrophy;RMetabolicRrateRisRrais
ed,RresultingRinRincreasedRheatRproduction,RincreasedRbodyRtemperature,RintoleranceRtoRheat,RandRskinRth
atRisRwarmRandRmoist.RAppetiteRisRincreased,RbutRweightRlossRmayRstillRoccur.
WhenRshouldRyouRre-checkRlabsRafterRinitiatingRLevothyroxine?R-RCORRECTRANSWERR-TSHR6-
8RweeksRafterRinitiationRorRdoseRchanges.
S/SRofRThyrotoxicRCrisisR(ThyroidRStorm)R-RCORRECTRANSWERR-
profoundRhyperthermiaR(105°FRorRevenRhigher),RsevereRtachycardia,Rrestlessness,Ragitation,RandRtremor.RU
nconsciousness,Rcoma,Rhypotension,RandRheartRfailureRmayRoccur
*ExcessiveRlevelsRofRthyroidRhormonesR(occursRafterRsurgeryRorRintercurrentRillnessR(e.g.Rsepsis)
TreatmentRofRthyroidRstormR-RCORRECTRANSWERR-*MEDICALREMERGENCY*R
1.HighRdosesRofRpotassiumRiodideRorRstrongRiodineRsolutionRareRgivenRtoRsuppressRthyroidRhormoneRreleas
e.R
2.MethimazoleRisRgivenRtoRsuppressRthyroidRhormoneRsynthesis.R3.ARβ-
blockerRisRgivenRtoRreduceRheartRrate.R
AdditionalRmeasuresRincludeRsedation,Rcooling,RandRgivingRglucocorticoidsRandRIVRfluids.
,WhatRcanRresultRfromRnotRtreatingRhypothyroidismRduringRpregnancy?R-RCORRECTRANSWERR-
permanentRneuropsychologicalRdeficitsRinRtheRchild
TreatmentRofRhyperthyroidismR-RCORRECTRANSWERR-1.RsurgicalRremovalRofRthyroidRtissue
2.RdestructionRofRthyroidRtissueRwithRradioactiveRiodineR(preferredRforRadults)
3.RantithyroidRdrugR(methimazoleRorRpropylthiouracil).R(preferredRforRyoungerRpatients)R
β-BlockersRsuppressRtachycardiaRbyRblockingRβ-receptorsRonRtheRheart.
NonradioactiveRiodineRinhibitsRsynthesisRandRreleaseRofRthyroidRhormones.
DrugsRthatRreduceRabsorptionRofRlevothyroxineR-RCORRECTRANSWERR-
HistamineR2R(H2)RreceptorRblockersR(e.g.,RcimetidineR[Tagamet])
ProtonRpumpRinhibitorsR(e.g.,RlansoprazoleR[Prevacid])
SucralfateR(Carafate)
CholestyramineR(Questran)
ColestipolR(Colestid)
Aluminum-containingRantacidsR(e.g.,RMaalox,RMylanta)
CalciumRsupplementsR(e.g.,RTums,ROs-Cal)
IronRsupplementsR(e.g.,RferrousRsulfate)
MagnesiumRsalts
OrlistatR(Xenical)
*administerR4RhoursRapartRfromRlevothyroxine*
FoodRinteractionsRwithRlevothyroxineR-RCORRECTRANSWERR-
FoodRdecreasesRabsorption.RShouldRbeRtakenRonRanRemptyRstomachR30-60RminutesRpriorRtoRbreakfast
DrugsRthatRaccelerateRlevothyroxineRmetabolismR-RCORRECTRANSWERR-phenytoinR(Dilantin)
carbamazepineR(Tegretol,RCarbatrol)
, rifampinR(Rifadin)
sertralineR(Zoloft)
phenobarbital.
*ToRmaintainRadequateRlevothyroxineRlevels,RpatientsRtakingRtheseRdrugsRmayRneedRtoRincreaseRtheirRlevo
thyroxineRdosage.
*DigoxinRandRInsulinRmayRhaveRmoreRrequirementsRwhenRtakingRlevothyroxine
WhichRlaboratoryRtestsRshouldRbeRcompletedRbeforeRprescribingRmethimazole?R-RCORRECTRANSWERR-
freeRtriiodothyronineR(T3)
freeRthyroxineR(T4)
LFTs
thyroid-stimulatingRhormoneR(TSH)
CBC
WhichRagentRisRtheRpreferredRtreatmentRoptionRforRthyroidRstorm?R-RCORRECTRANSWERR-
PTUR(propylthiouracil)
WhichRagentRisRtheRfirst-lineRtreatmentRforRhyperthyroidismRorRGrave'sRdisease?R-RCORRECTRANSWERR-
methimazole
HowRtoRconfirmRdiabetesRdiagnosisR-RCORRECTRANSWERR-FastingRplasmaRglucoseR≥126Rmg/dLa
Or
RandomRplasmaRglucoseR≥R200Rmg/dLRplusRsymptomsRofRdiabetesb
Or
OralRglucoseRtoleranceRtestR(OGTT):R2-hRplasmaRglucoseR≥200Rmg/dLc
or
HemoglobinRA1cR6.5%RorRhigherR(STANDARDRTEST)