NR565 WEEK 5 QUESTIONS WITH CORRECT ANSWERS 2025

NR565 WEEK 5 QUESTIONS WITH CORRECT
ANSWERS 2025
SignsMandMsymptomsMofMhypothyroidismMandMhyperthyroidismM-MCORRECTMANSWERM-Hypothyroidism:

Thick,Mcoarse,MdryMHyporeflexia,M"hungMup"MpatellaMreflexMSlowMthoughtMprocess,MWeightMgainM(5-
10Mlbs./2.25-4.5Mkg)MConstipation,MMenorrhagia,MColdMintolerance:MColdMallMtheMtime



HyperthyroidismM(akaMgravesMdisease):

Smooth,MsilkyMHyperreflexia,MMindMracing,MWeightMlossM(10Mlbs./4.5Mkg)MDiarrhea,Mloose,MfrequentMstool
s,MOligomenorrhea,MHeatMintolerance:MHotMallMtheMtime



pg.M418-419



WhatMadjunctiveMtherapyMisMgoodMtoMprescribeMtoMcontrolMsymptomsMofMhyperthyroidismMotherMthanMt
hyroidMspecificMmedications?M

KnowMdrugMclassesMandMexamplesMofMthoseMdrugMclasses.M-MCORRECTMANSWERM-β-
BlockersMandMnonradioactiveMiodineMmayMbeMusedMasMadjunctiveMtherapy.Mβ-
BlockersMsuppressMtachycardiaMbyMblockingMβ-
receptorsMonMtheMheart.MNonradioactiveMiodineMinhibitsMsynthesisMandMreleaseMofMthyroidMhormones.

pg.M419



MonitoringMneedsMandMintervalsMforMthyroidMmedications.M-MCORRECTMANSWERM-levothyroxine-
Monitoring:MCheckMTSHM6-
8MweeksMafterMinitiatingMtherapyMandMafterManyMdosageMchange.MCheckMTSHMatMleastMonceMaMyearMafterM
serumMTSHMisMstabilized.



Methimazole-
Monitoring:MCheckMCBCMwithMdifferentialMifMsignsMorMsymptomsMofMinfection.MCheckMLFTsMifMsignsMorMsy
mptomsMofMliverMdysfunction.



PropylthiouracilM(PTU)-MTreatmentMcontinuesMforM1-2Myears

PTUMhasMcausedMrareMcasesMofMliverMinjury.MOnsetMisMsuddenMandMprogressionMisMrapid.

,-
MPropylthiouracilM(PTU)McarriesMaMriskMforMliverMtoxicity.MAlthoughMrare,MtheMFDAMrecommendsMagainstMu
singMPTUMasMaMfirst-lineMtreatmentMdueMtoMpotentialMforMhepaticMtoxicity.M-MCORRECTMANSWERM-
TreatmentMcontinuesMforM1-2Myears

PTUMhasMcausedMrareMcasesMofMliverMinjury.MOnsetMisMsuddenMandMprogressionMisMrapid.MpgM421



-
MEffectsMofMmaternalMhypothyroidismMonMoffspringMandMappropriateMpatientMteachingMrelatedMtoMneedMf
orMtreatment.M-MCORRECTMANSWERM-
MaternalMhypothyroidismMcanMresultMinMpermanentMneuropsychologicalMdeficitsMinMtheMchild.



canMdecreaseMIQMandMotherMaspectsMofMneuropsychologicalMfunctionMinMtheMchild.



teaching:

toMhelpMensureMhealthyMfetalMdevelopment,MmaternalMhypothyroidismMmustMbeMdiagnosedMandMtreated
MveryMearly.




someMauthoritiesMcurrentlyMrecommendMroutineMscreeningMforMhypothyroidismMasMsoonMasMpregnancyMi
sMconfirmed.MIfMhypothyroidismMisMdiagnosed,MreplacementMtherapyMshouldMbeginMimmediately.



theMsignsMandMsymptomsMofMpregnancyMmimicsMthoseMofMhypothyroidism



WhenMwomenMtakingMthyroidMsupplementsMbecomeMpregnant,MdosageMrequirementsMusuallyMincrease
—
oftenMbyMasMmuchMasM50%.MTheMneedMforMincreasedMdosageMbeginsMbetweenMweeksM4MandM8MofMgestati
on,MlevelsMoffMatMapproximatelyMweekM16,MandMthenMremainsMsteadyMuntilMparturition.



pg.M418



-MPatientMteachingMforMthyroidMmedications.M-MCORRECTMANSWERM-:levothyroxine:M

shouldMbeMtakenMonManMemptyMstomachMinMtheMmorning,MatMleastM30MtoM60MminutesMbeforeMbreakfast.

, InformMpatientsMaboutMtheMsymptomsMofMthyrotoxicosisMandMinstructMthemMtoMnotifyMtheMprescriberMifM
theseMdevelopM(Sweating,Mirritability,MweightMloss,Mtachycardia)InstructMpatientsMtoMseparateMadministra
tionMofMlevothyroxineMandMtheseMdrugsMbyM4Mhours



OverdoseMmayMcauseMthyrotoxicosis.MSymptomsMincludeMtachycardia,Mangina,Mtremor,Mnervousness,Mins
omnia,Msweating,MandMheatMintolerance.



methamizole:

Agranulocytosis:MInformMpatientsMaboutMearlyMsignsMofMagranulocytosis,MincludingMfeverMorMsoreMthroat.
MIfMfollow-upMbloodMtestsMrevealMleukopenia,MmethimazoleMshouldMbeMstopped.



Hypothyroidism:MMethimazoleMmayMcauseMexcessiveMreductionsMinMthyroidMhormoneMsynthesis.MIfMsigns
MofMhypothyroidismMdevelopMorMifMplasmaMlevelsMofMT3MandMT4MbecomeMsubnormal,MdosageMshouldMbeM

reduced.



RadioactiveMIodine:

InformMpatientsMaboutMsymptomsMofMiodism,MincludingMbrassyMtaste,MburningMsensationsMinMtheMmouth,
MandMsorenessMofMgumsMandMteeth.MIodineMcanMalsoMcauseMcorrosiveMinjuryMtoMtheMGIMtract.MInstructMpa

tientsMtoMnotifyMtheMprescriberMifMsevereMabdominalMdistressMdevelops.



PTU:

canMcauseMrareMcasesMofMliverMinjury



WhatMdrugMclassMcanMinterfereMwithMtheMassessmentMandMmonitoringMofMdiabetesMandMwhy?M

oMYouMwillMneedMconnectMpathophysiologyMinformationMofMmedicationsMandMdiabetesMtogether.MThinkMa
boutMalphaMandMbetaMcells.M-MCORRECTMANSWERM-HypoglycemicMagents.

DrugsMthatMlowerMbloodMglucoseMlevelsMcanMintensifyMhypoglycemiaMinducedMbyMinsulin.MAmongMtheseM
drugsMareMsulfonylureas,Mglinides,MandMalcoholM(usedMacutelyMorMlongMtermMinMexcessiveMdoses).MWhenM
theseMdrugsMareMcombinedMwithMinsulin,MspecialMcareMmustMbeMtakenMtoMensureMasMbestMasMpossibleMth
atMbloodMglucoseMdoesMnotMfallMtooMlow.



HyperglycemicMagents.

DrugsMthatMraiseMbloodMglucoseM(e.g.,MthiazideMdiuretics,Mglucocorticoids,Msympathomimetics)McanMcoun
teractMtheMdesiredMeffectsMofMinsulin.MWhenMtheseMagentsMareMcombinedMwithMinsulin,MinsulinMdosageM
mayMneedMtoMbeMincreased.