Tuesday, October 25, 2022!
Bio Mitosis (unit 3)
Subject!
- Gametes sexual production !
- Somatic are not !
Mitosis cell division, growth & repair- think of babies -!
Meiosis carries half of genetics -Sperm + egg = zygote Meiosis : reproduction;
gametes & genetic variability !
-Mitosis grows the human body ; Average adult body contains between 30-40 trillion
cells ;!
——————How much skin do you shed per year = 3 burgers !
Apoptosis: programmed cell death - Mitosis & apop work together !
Apop; cell death is an essential part of life ;its carves out structure !
The cell cycle!
• Interphase : Growth (G1): newly divided cell grows, Normal cell functions resume !
• G0 phase : Normal cell function , no Dan relocation ,no division !
• ,Dan replication (S), Growth (G2)!
• Chromosomes : homologues are similar but not identical ( non-replicated
chromosomes ) Replication ( S-phase )——> Sister chromatids (end of S phase to
M; G2 through metaphase replicated chromosomes ( sister chromatids))!
• G2 phase !
• M phase ; mitosis ( division of nucleus ) ; Cytokinesis ( division of cell)!
• Cancer cells : If the cell don’t do something they have to apoptosis - Pro oncogenes
promote normal cell division when mutated they can become oncogenes - Tumor
suppressor genes regulate checkpoints ; when muted they can’t stop the cell cycle !
• Normal cell ; pro oncogene + mutated = Oncogene (which is hyperactive ) if not ,
normal cells = normal protein stimulate cell division !
1
, • P53 gene : tumor suppressor + mutated = inactive (broken) ; Normal cell —-. Normal
proteins block cancer development !
• Growth factors example is like when your brake don’t work on your car it keeps going
with out stopping !
• Target for anti cancer drugs - actin molecule !
•
2
Bio Mitosis (unit 3)
Subject!
- Gametes sexual production !
- Somatic are not !
Mitosis cell division, growth & repair- think of babies -!
Meiosis carries half of genetics -Sperm + egg = zygote Meiosis : reproduction;
gametes & genetic variability !
-Mitosis grows the human body ; Average adult body contains between 30-40 trillion
cells ;!
——————How much skin do you shed per year = 3 burgers !
Apoptosis: programmed cell death - Mitosis & apop work together !
Apop; cell death is an essential part of life ;its carves out structure !
The cell cycle!
• Interphase : Growth (G1): newly divided cell grows, Normal cell functions resume !
• G0 phase : Normal cell function , no Dan relocation ,no division !
• ,Dan replication (S), Growth (G2)!
• Chromosomes : homologues are similar but not identical ( non-replicated
chromosomes ) Replication ( S-phase )——> Sister chromatids (end of S phase to
M; G2 through metaphase replicated chromosomes ( sister chromatids))!
• G2 phase !
• M phase ; mitosis ( division of nucleus ) ; Cytokinesis ( division of cell)!
• Cancer cells : If the cell don’t do something they have to apoptosis - Pro oncogenes
promote normal cell division when mutated they can become oncogenes - Tumor
suppressor genes regulate checkpoints ; when muted they can’t stop the cell cycle !
• Normal cell ; pro oncogene + mutated = Oncogene (which is hyperactive ) if not ,
normal cells = normal protein stimulate cell division !
1
, • P53 gene : tumor suppressor + mutated = inactive (broken) ; Normal cell —-. Normal
proteins block cancer development !
• Growth factors example is like when your brake don’t work on your car it keeps going
with out stopping !
• Target for anti cancer drugs - actin molecule !
•
2
