Antibiotics affect communities - ANSWER antibiotics affect overall microbial
communities
In this study, it was found that the diversity of the community, rather than
density, was reduced by antibiotics ( panel A control, pane B treated with
antibiotics)
Alterng the intestinal microbiota during a critical developmental window has
lasting metabolic consequences - ANSWER findings:
low dose penicillin enhances effect of high fat diet-induced obesity
transferrable to germ-free hosts
phenotypes persists, despite recovery of microbial communities
antibiotics and agriculture
Prebiotics - ANSWER a non digestable food item that promotes growth of
healthy microbes in gut
Importance of metabolites - ANSWER nutrient availability reflects microbial
community
kwashiorkor, severe malnutrition, can be transplanted to mice by fecal
transplantation
microbes supply vitamine K, Vit B12, biotin, folate, thiamine, riboflavin, and
pyridoxine
metagenomic analysis allows correlations beteen microbes and metabolites to
be established
Fecal transplant - ANSWER initially utilized to treat pseudomembranous
enterocolitis
often caused by clostridium difficile
problems with antibiotic resistant C. Difficile
after treatment, the gut flora is very similar to that of the donor
rePOOPulation - ANSWER stool substitute transplant therapy for the
eradication of Clostridium difficile infection: RePOOPulating the gut
grow culture from healthy donors in a chemostat
selected 33 strains for transplanation
communities
In this study, it was found that the diversity of the community, rather than
density, was reduced by antibiotics ( panel A control, pane B treated with
antibiotics)
Alterng the intestinal microbiota during a critical developmental window has
lasting metabolic consequences - ANSWER findings:
low dose penicillin enhances effect of high fat diet-induced obesity
transferrable to germ-free hosts
phenotypes persists, despite recovery of microbial communities
antibiotics and agriculture
Prebiotics - ANSWER a non digestable food item that promotes growth of
healthy microbes in gut
Importance of metabolites - ANSWER nutrient availability reflects microbial
community
kwashiorkor, severe malnutrition, can be transplanted to mice by fecal
transplantation
microbes supply vitamine K, Vit B12, biotin, folate, thiamine, riboflavin, and
pyridoxine
metagenomic analysis allows correlations beteen microbes and metabolites to
be established
Fecal transplant - ANSWER initially utilized to treat pseudomembranous
enterocolitis
often caused by clostridium difficile
problems with antibiotic resistant C. Difficile
after treatment, the gut flora is very similar to that of the donor
rePOOPulation - ANSWER stool substitute transplant therapy for the
eradication of Clostridium difficile infection: RePOOPulating the gut
grow culture from healthy donors in a chemostat
selected 33 strains for transplanation
