with solutions 2025
warm ischemia time -O O O
ANSWER prior to organ removal when normothermic and after cold preservation prior to reperf
O O O O O O O O O O O O O O
usion
cold ischemia time -
O O O
OANSWER period from time of cooling organ to removal from cold preservation solution
O O O O O O O O O O O O
when does injury to transplanted organ happen? - ANSWER reperfusion -
O O O O O O O O O O
after cold ischemia when the organ is revascularized - ischemia reperfusion injury
O O O O O O O O O O O O
intracellular preservation solutions (3) - ANSWER Euro-Collins solution
O O O O O O O
HTK
University of Wisconsin solution O O O
all provide electrolyes that decrease cellular swelling during preservation time
O O O O O O O O O
which solution provides extended preservation of the liver and pancreas? -
O O O O O O O O O O
ANSWER University of Wisconsin solution
O O O O O
most common aberrant anatomy during KINDNEY transplant - ANSWER - kidney -
O O O O O O O O O O O
multiple renal arteries (10%)
O O O O
- lower pole of right renal artery passing in front of IVC rather than behind
O O O O O O O O O O O O O O
,-retroaortic left renal vein O O O
most common aberrant anatomy during LIVER transplant -
O O O O O O O
ANSWER aberrant right hepatic artery arising from the SMA (rather than celiac trunk)
O O O O O O O O O O O O O
most common aberrant anatomy during PANCREAS transplant -
O O O O O O O
ANSWER preduodenal portal vein
O O O O
annular pancreas O
portal vein duplication
O O
contraindications to organ donation for LIVING donors - ANSWER absolute:
O O O O O O O O O
- HIV and Hep (unless recipient positive)
O O O O O O
-cirrhosis
-active systemic infection with + blood cultures
O O O O O O
-melanoma
contraindications to organ donation for relativeLIVING donors -
O O O O O O O
OANSWER low grade visceral malignancies
O O O O
low grade brain tumors
O O O
history of abdominal surgery
O O O
UTI
, LIVING donor hepatectomy - contraindications - ANSWER *very healthy*
O O O O O O O O
no advanced cardiopulmonary disease
O O O
no advanced liver pathology
O O O
- no cancer history
O O O
-anatomic restraints - no aberrant biliary anatomy, etc
O O O O O O O
possible living donor hepatectomy grafts - ANSWER Right lobe (5-7)
O O O O O O O O O
left (2-4) O
left lateral (2-3)
O O
complications to living donor for hepatectomy - ANSWER -infections, bile leak, hernia
O O O O O O O O O O O
-liver failure O
-IVC thrombus O
postop maintenance for living donors - ANSWER - daily labs for a few days
O O O O O O O O O O O O O
- post op hepatic duplex
O O O O
-HIDA if concern for leak
O O O O
living vs deceased donor nephrectomy outcomes -
O O O O O O
OANSWER recipient outcomes and graft survival are BETTER with living donor.
O O O O O O O O O O O
less time on waiting list as well
O O O O O O
contraindications to living donor nephrectomy - O O O O O
OANSWER active/incompletely treated malignancy or infections
O O O O O