High-Yield and Frequently Missed ABSITE questions and answers with solutions 2025

Breast: What is presentation, treatment, prognosis for intraductal papilloma? -
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OANSWER presents with bleeding/bloody nipple discharge (most common cause), usually benign
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, biopsy/resect via major duct excision
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Breast: What are contraindications to BCT (lumpectomy) in stage I breast cancer (and what speci
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fically is not)? - ANSWER 1) prior irradiation;
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2) pos margins;
O O O




3) inflammatory;
O O




4) pregnancy (unless 3rd trimester)
O O O O




Breast: what are the axillary node levels (1-3, and one more category)? - ANSWER 1 -
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lateral to pec minor;
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2 - beneath pec minor;
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3 - medial to pec minor;
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Rotter's Nodes - between pec major and pec minor
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Breast: when is SNLB indicated (size, nodes, tumor status, metastatic risk)>? -
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ANSWER >1 cm, no positive nodes (obviously), primary tumor present, low risk of axillary mets,
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Breast: what do you do if you can't find radiotracer dye in SNLB? -
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ANSWER have to do formal ALND
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Breast: what is treatment for DCIS in male/female? - ANSWER female --
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BCT + xrt OR mastectomy; male -- mastectomy
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Breast: what is not needed for patient with negative SLNB? - ANSWER ALND --
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just do BCT or mastectomy depending on tumor is fine
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,Breast: what patient would get only mastectomy/BCT + tamoxifen for 5 years (4 characteristics)?
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- ANSWER negative SLN, old, ER+, and tumor <2 cm
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Breast: what patient would get mastectomy/BCT + tamoxifen for 5 years plus chemo (4 characte
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ristics)? - ANSWER negative SLN, young, ER+, and tumor >1cm
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Breast: what are 3 chemo agents used for breast CA typically? -
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ANSWER 1) adriamycin; 2) cyclophosphamide; 3) taxol
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Breast: what patient would get mastectomy/BCT + chemo (no tamoxifen)? -
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ANSWER negative SLN, ER-
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Breast: what is main SE of taxol? - ANSWER taxol - neuropathy
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Breast: what is main SE of adriamycin (doxorubacin)? - ANSWER cardiomyopathy
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Breast: what is treatment for inflammatory breast cancer (in order)? -
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ANSWER neoadjuvant chemo, then mastectomy (mod radical), then XRT
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Breast: what options are available for breast mass post neoadjuvant therapy? -
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OANSWER same as de novo breast cancer -- BCT or mastectomy --
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Oif tumor shrunk and now amenable to BCT, that's fine, even if it was big before and needed mas
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tectomy based on size O O O




Breast: LCIS -- O O



who primarily gets this, what is most important characteristic, what % get cancer, where, and w
O O O O O O O O O O O O O O O O



hat type? - ANSWER - pre-menopausal
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- NOT premalignant itself
O O O

,- 30% lifetime risk
O O O




70% ductal CA O O




Breast: LCIS -- what % have synchronous cancer? - ANSWER 5%
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Breast: LCIS -- what is treatment (4 possibility, 2 things not needed ever)? -
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ANSWER 1) Need to resect the lesion but do not need neg margins
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2) nothing and careful F/U
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3) Hormonal therapy
O O




O -(pre-meno: tamoxifen; Post-meno: raloxifene) O O O




4) bilateral subcutaneous mastectomy (no ALND)
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Breast: What are the benign proliferative breast lesions that have increased risk of CA? (3)
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Tx? - ANSWER - LCIS
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- Atypical ductal hyperplasia
O O O




- atypical lobular hyperplasia
O O O




Tx: resect the lesion w/ (-) margins
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Breast: for atypical ductal hyperplasia; atypical lobular hyperplasia; LCIS, how are these characte
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rized and what treatment should be considered? -
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OANSWER benign proliferative dz. Incr risk of CA.
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Need to resect - don't need (-) margins
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Can give hormone therapy
O O O




- pre-meno: tamoxifen
O O




- post-meno: raloxifene
O O




Bilateral total mastectomy (no ALND)
O O O O

, Liver: amebic abscess - how does organism enter, what organism is it -
O O O O O O O O O O O O



OANSWER through portal systemO O O




Liver: amebic abscess - what are 3 presenting symptoms? -
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OANSWER fever, RUQ pain, RUQ tenderness
O O O O O




Liver: amebic abscess - what test may help diagnose? - ANSWER indirect hemagglutination
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Liver: amebic abscess -
O O O



Owhat is first line treatment, when should surgery be done, and what other option exists? -
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OANSWER first option metronidazole -- surgery or percutaneous drainage if failure
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Liver: what are 2 primary routes for pyogenic liver abscess, and what are 2 specific causes for ea
O O O O O O O O O O O O O O O O O



ch? - ANSWER biliary infection (cholecystitis/cholangitis) - most common
O O O O O O O O




seeding from portal vein drainage (appendicitis, diverticulitis)
O O O O O O




Liver: pyogenic abscess - what are most common organisms (3)? -
O O O O O O O O O O



OANSWER e. coli, klebsiella, strep
O O O O




Liver: treatment for pyogenic abscess (variuos options)? -
O O O O O O O



OANSWER abx and/or percutaneous drainage, always search for primary source
O O O O O O O O O




Liver: echinococcal abscess - what is treatment? -
O O O O O O O



OANSWER Antiparasitics (albendazole/mabendazole)
O O




PA - Perc aspiration
O O O




I - inject (w/ hypertonic saline or alcohol)
O O O O O O O




R - resect
O O