Test bank for clayton s basic pharmacology for nurses 18th edition willihnganz full chapter

,DOWNLOAD THE Test Bank for Clayton's Basic Pharmacology for Nurses 18thEditio
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Chapter 02: Basic Principles of Drug Action and Drug Interactions
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mWillihnganz: Clayton’s Basic Pharmacology for Nurses, 18th Editi
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MULTIPLEmCHOICE

1. Themnursemassessesmhivesminmampatientmstartedmonmamnewmmedication.mWhatmismthemnurse’smprio
ritymaction?
a. Notifymphysicianmofmallergicmreaction.
b. Notifymphysicianmofmidiosyncraticmreaction.
c. Notifymphysicianmofmpotentialmteratogenicity.
d. Notifymphysicianmofmpotentialmtolerance.
ANS:m A
Anmallergicmreactionmismindicativemofmhypersensitivitymandmmanifestsmwithmhivesmand/ormurticari
a,mwhichmaremeasilymidentified.mAnmidiosyncraticmreactionmoccursmwhenmsomethingmunusualmorm
abnormalmhappensmwhenmamdrugmismfirstmadministered.mAmteratogenicmreactionmrefersmtomthemocc
urrencemofmbirthmdefectsmrelatedmtomadministrationmofmthemdrug.mTolerancemrefersmtomthembody’smr
equirementmformincreasingmdosagesmtomachievemthemsamemeffectsmthatmamlowermdosemoncemdid.

DIF: CognitivemLevel:mApplication REF:mmmp.m17
OBJ:m4mNAT:m NCLEXmClientmNeedsmCategory:mPhysiologicalmInteg
rity
TOP:m NursingmProcessmStep:mAssessment CON:m ClinicalmJudgmentm|mSafety

2. Themnursemadministersmanminitialmdosemofmamsteroidmtomampatientmwithmasthma.mThirtymminutesma
ftermadministration,mthemnursemfindsmthempatientmagitatedmandmstatingmthatm“everyonemismoutmtomg
etmme.”mWhatmismthemtermmformthismunusualmreaction?
a. Desiredmaction
b. Adversemeffect
c. Idiosyncraticmreaction
d. Allergicmreaction
ANS:m C
Idiosyncraticmreactionsmaremunusual,mabnormalmreactionsmthatmoccurmwhenmamdrugmismfirstm
administered.mPatientsmtypicallymexhibitmanmoverresponsivenessmtomammedicationmrelatedmt
omdiminishedmmetabolism.mThesemreactionsmarembelievedmtombemrelatedmtomgeneticmenzyme
mdeficiencies.mDesiredmactionsmaremexpectedmresponsesmtomammedication.mAdversemeffectsm

aremreactionsmthatmoccurminmanothermsystemmofmthembody;mtheymaremusuallympredictable.mAll
ergicmreactionsmappearmaftermrepeatedmmedicationmdosages.

DIF: CognitivemLevel:mKnowledge REF:mmmp.m18
OBJ:m4mNAT:m NCLEXmClientmNeedsmCategory:mPhysiologicalmInteg
rity
TOP:m NursingmProcessmStep:mEvaluation
CON:m PatientmEducationm|mClinicalmJudgmentm|mCaregivingm|mSafetym|mSensorymPerception

3. Whichmismthembestmdescriptionmofmwhenmdrugminteractionsmoccur?
a. Onmadministrationmofmtoxicmdosagesmofmamdrug
b. Onmanmincreaseminmthempharmacodynamicsmofmboundmdrugs
c. Onmthemalterationmofmthemeffectmofmonemdrugmbymanothermdrug
d. Onmincreasemofmdrugmexcretion


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,DOWNLOAD THE Test Bank for Clayton's Basic Pharmacology for Nurses 18thEditio
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n Willihnganz
m
ANS:m C




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, DOWNLOAD THE Test Bank for Clayton's Basic Pharmacology for Nurses 18thEditio
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Drugminteractionsmmaymbemcharacterizedmbymanmincreasemormdecreaseminmthemeffectivenessmofm
onemormbothmofmthemdrugs.mToxicitymofmonemdrugmmaymormmaymnotmaffectmthemmetabolismmofman
othermone.mDrugminteractionsmmaymresultmfrommeithermincreasedmormdecreasedmpharmacodyna
mics.
Drugminteractionsmmaymresultmfrommeithermincreasedmormdecreasedmexcretion.

DIF: CognitivemLevel:mComprehension REF:mmmp.m18
OBJ:m5mNAT:m NCLEXmClientmNeedsmCategory:mPhysiologicalmInteg
rity
TOP:m NursingmProcessmStep:mAssessment CON:m Safetym|mPatientmEducationm|mClinicalmJudgment

4. Whatmoccursmwhenmtwomdrugsmcompetemformthemsamemreceptormsite,mresultingminmincreas
edmactivitymofmthemfirstmdrug?
a. Desiredmaction
b. Synergisticmeffect
c. Carcinogenicity
d. Displacement
ANS:m D
Themdisplacementmofmthemfirstmdrugmfrommreceptormsitesmbymamsecondmdrugmincreasesmthemamo
untmofmthemfirstmdrugmbecausemmoremunboundmdrugmismavailable.mAnmexpectedmresponsemofmamd
rugmismthemdesiredmaction.mAmsynergisticmeffectmismthemeffectmofmtwomdrugsmbeingmgreatermthanm
themeffectmofmeachmchemicalmindividuallymormthemsummofmthemindividualmeffects.mCarcinogenici
tymismthemabilitymofmamdrugmtomcausemcellsmtommutatemandmbecomemcancerous.

DIF: CognitivemLevel:mComprehension REF:mmmp.m19
OBJ:m6mNAT:m NCLEXmClientmNeedsmCategory:mPhysiologicalmInteg
rity
TOP:m NursingmProcessmStep:mImplementation CON:mSafetym|mPatientmEducation

5. Whatmdomdrugmbloodmlevelsmindicate?
a. Theymconfirmmifmthempatientmismtakingmamgenericmformmofmamdrug.
b. Theymdeterminemifmthempatientmhasmsufficientmbodymfatmtommetabolizemthemdrug.
c. Theymverifymifmthempatientmismtakingmsomeonemelse’smmedications.
d. Theymdeterminemifmthemamountmofmdrugminmthembodymisminmamtherapeuticmrange.
ANS:m D
Themamountmofmdrugmpresentmmaymvarymovermtimemandmthembloodmlevelmmustmremainminmamthera
peuticmrangeminmordermtomobtainmthemdesiredmresult.mGenericmdrugsmdomnotmnecessarilymproducem
amdifferentmdrugmbloodmlevelmthanmproprietarymmedications.mBodymfatmismnotmmeasuredmbymdrug
mbloodmlevels.mDrugmbloodmlevelsmonlymmeasuremthemamountmofmdrugminmthembody;mtheymdom notm
determinemthemsourcemofmthemmedication.

DIF: CognitivemLevel:mComprehension REF:mmmp.m17
OBJ:m3mNAT:m NCLEXmClientmNeedsmCategory:mPhysiologicalmInteg
rity
TOP:m NursingmProcessmStep:mEvaluation CON:m ClinicalmJudgmentm|mSafety

6. Whatmismthemprocessmbymwhichmamdrugmismtransportedmbymcirculatingmbodymfluidsmtomreceptormsite
s?
a. Osmosis
b. Distribution
c. Absorption
d. Biotransformation

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