Pharmacology Exam 3 practice UPDATED
Exam Questions and CORRECT Answers
A young couple (25-year-old male, 23-year-old female) wants to start a family. They have not
conceived after 1 yr of unprotected intercourse. Infertility evaluation revealed no abnormalities
in the female partner and low sperm count in the male. Which of the following is a drug that is
purified from the urine of postmenopausal women and is used to promote spermatogenesis in
infertile men?
(A) Desmopressin
(B) Gonadorelin
(C) Goserelin
(D) Somatropin
(E) Urofollitropin - CORRECT ANSWER - (E) Urofollitropin
A 29-year-old woman in her 41st wk of gestation had been in labor for 12 h. Although her uterine
contractions had been strong and regular initially, they had diminished in force during the past
hour. Which of the following agents would be used to facilitate this woman's labor and delivery?
(A) Dopamine
(B) Leuprolide
(C) Oxytocin
(D) Prolactin
,(E) Vasopressin - CORRECT ANSWER - (C) Oxytocin
A 3-year-old boy with failure to thrive and metabolic disturbances was found to have an
inactivating mutation in the gene that encodes the growth hormone receptor. Which of the
following drugs is most likely to improve his metabolic function and promote his growth?
(A) Atosiban
(B) Bromocriptine
(C) Mecasermin
(D) Octreotide
(E) Somatropin - CORRECT ANSWER - (C) Mecasermin
An important difference between leuprolide and ganirelix is that ganirelix
(A) Can be administered as an oral formulation
(B) Can be used alone to restore fertility to hypogonadal men and women
(C) Immediately reduces gonadotropin secretion
(D) Initially stimulates pituitary production of LH and FSH
(E) Must be administered in a pulsatile fashion - CORRECT ANSWER - (C) Immediately
reduces gonadotropin secretion
, A 27-year-old woman with amenorrhea, infertility, and galactorrhea was treated with a drug that
successfully restored ovulation and menstruation. Before being given the drug, the woman was
carefully questioned about previous mental health problems, which she did not have. She was
advised to take the drug orally. Which of the following is most likely to be the drug that was used
to treat this patient?
(A) Bromocriptine
(B) Desmopressin
(C) Human gonadotropin hormone
(D) Leuprolide
(E) Octreotide - CORRECT ANSWER - (A) Bromocriptine
A 3-year-old girl was referred to the genetic counselor by her pediatrician. She presents with
short stature (height is 85 cm, -3 standard deviations) and appears to have loose skin on her neck.
Cytogenetic testing reveals an XO karyotype. Which of the following drugs will allow her to
achieve a higher adult height?
(A) Adrenocorticotropin (ACTH)
(B) Corticotropin-releasing hormone (CRH)
(C) Growth hormone-releasing hormone (GHRH)
(D) Gonadotropin-releasing hormone (GnRH)
Exam Questions and CORRECT Answers
A young couple (25-year-old male, 23-year-old female) wants to start a family. They have not
conceived after 1 yr of unprotected intercourse. Infertility evaluation revealed no abnormalities
in the female partner and low sperm count in the male. Which of the following is a drug that is
purified from the urine of postmenopausal women and is used to promote spermatogenesis in
infertile men?
(A) Desmopressin
(B) Gonadorelin
(C) Goserelin
(D) Somatropin
(E) Urofollitropin - CORRECT ANSWER - (E) Urofollitropin
A 29-year-old woman in her 41st wk of gestation had been in labor for 12 h. Although her uterine
contractions had been strong and regular initially, they had diminished in force during the past
hour. Which of the following agents would be used to facilitate this woman's labor and delivery?
(A) Dopamine
(B) Leuprolide
(C) Oxytocin
(D) Prolactin
,(E) Vasopressin - CORRECT ANSWER - (C) Oxytocin
A 3-year-old boy with failure to thrive and metabolic disturbances was found to have an
inactivating mutation in the gene that encodes the growth hormone receptor. Which of the
following drugs is most likely to improve his metabolic function and promote his growth?
(A) Atosiban
(B) Bromocriptine
(C) Mecasermin
(D) Octreotide
(E) Somatropin - CORRECT ANSWER - (C) Mecasermin
An important difference between leuprolide and ganirelix is that ganirelix
(A) Can be administered as an oral formulation
(B) Can be used alone to restore fertility to hypogonadal men and women
(C) Immediately reduces gonadotropin secretion
(D) Initially stimulates pituitary production of LH and FSH
(E) Must be administered in a pulsatile fashion - CORRECT ANSWER - (C) Immediately
reduces gonadotropin secretion
, A 27-year-old woman with amenorrhea, infertility, and galactorrhea was treated with a drug that
successfully restored ovulation and menstruation. Before being given the drug, the woman was
carefully questioned about previous mental health problems, which she did not have. She was
advised to take the drug orally. Which of the following is most likely to be the drug that was used
to treat this patient?
(A) Bromocriptine
(B) Desmopressin
(C) Human gonadotropin hormone
(D) Leuprolide
(E) Octreotide - CORRECT ANSWER - (A) Bromocriptine
A 3-year-old girl was referred to the genetic counselor by her pediatrician. She presents with
short stature (height is 85 cm, -3 standard deviations) and appears to have loose skin on her neck.
Cytogenetic testing reveals an XO karyotype. Which of the following drugs will allow her to
achieve a higher adult height?
(A) Adrenocorticotropin (ACTH)
(B) Corticotropin-releasing hormone (CRH)
(C) Growth hormone-releasing hormone (GHRH)
(D) Gonadotropin-releasing hormone (GnRH)
