VTHT 2223 Questions 3 Exam 100% Solved
F II - ANSWER Prothrombin
Citrate - ANSWER 1 part citrate to 9 parts whole blood available in 3.2% and 3.8%
Sample handling - ANSWER - Label and transfer ASAP
- Hold at room temp, tightly capped, kept upright.
- Avoid vibrational trauma.
Thrombocytopenia - ANSWER Decreased platelets
Other considerations for platelet counts - ANSWER - Observe morphologic change for
aggregation or giant platelets look for reticulated platelets.
Reticulated platelets - ANSWER Newly released with high levels of RNA.
Increases in MPV - ANSWER - increased loss, destruction or consumption
- not useful in cats (already larger)
- breed specific
- altered by exposure to EDTA
Plateletcrit or thrombocrit - ANSWER Measure of the percentage of the total blood
volume comprised of platelets.
Plateletcrit or thrombocrit Determined by - ANSWER Multiplying total platelet count by
the mean platelet volume normally less than 1% in mammals.
Prolonged OSPT - ANSWER - severe liver disease
- DIC
- hereditary or acquired deficiencies of any factors
- vitamin K
von Willebrand factor - ANSWER - vWF required for platelet adhesion
- performed when platelet function defects are evident
- immunoassays in reference laboratories
Causes of Thrombocytopenia - ANSWER - viral infection
- bacterial infection
, - parasitic infection
- medications like aspirin or acetaminophen
Hemostasis - ANSWER the ability of the body's systems to maintain the integrity of the
blood and blood vessels
Hemostasis involves - ANSWER - a number of complex pathways
- platelets
- coagulation factors
Mechanical phase - ANSWER - initiated when blood vessel is ruptured or torn
- exposed subendothelium of vessel is charged
- platelets are attracted to charged surface
Platelets at charged surface - ANSWER - undergo morphologic and physiologic changes
- causes:
adhere to each other and endothelium once activated expose phosphatidylserine on
their outer membrane.
von Willebrand factor - ANSWER - stabalizes the platelet plug
- large glycoprotein that circulates with F VIII and aids in platelet aggregation at the
beginning of the coagulation pathway
Trigger for chemical phase - ANSWER Adhesion and aggregation of platelets
Coagulation Cascade - ANSWER involves a number of factors both intrinsic and
extrinsic pathways results in a fibrin mesh or clot.
F VII - ANSWER proconvertin
F VIII - ANSWER Antihemophilic factor
F IX - ANSWER Plasma thromboplastin Christmas factor
F XI - ANSWER - plasma
- thromboplastin
- antecedent
F XII - ANSWER Hageman factor
Sample collection for coagulation tests - ANSWER - minimize tissue damage
- minimal venous stasis
F II - ANSWER Prothrombin
Citrate - ANSWER 1 part citrate to 9 parts whole blood available in 3.2% and 3.8%
Sample handling - ANSWER - Label and transfer ASAP
- Hold at room temp, tightly capped, kept upright.
- Avoid vibrational trauma.
Thrombocytopenia - ANSWER Decreased platelets
Other considerations for platelet counts - ANSWER - Observe morphologic change for
aggregation or giant platelets look for reticulated platelets.
Reticulated platelets - ANSWER Newly released with high levels of RNA.
Increases in MPV - ANSWER - increased loss, destruction or consumption
- not useful in cats (already larger)
- breed specific
- altered by exposure to EDTA
Plateletcrit or thrombocrit - ANSWER Measure of the percentage of the total blood
volume comprised of platelets.
Plateletcrit or thrombocrit Determined by - ANSWER Multiplying total platelet count by
the mean platelet volume normally less than 1% in mammals.
Prolonged OSPT - ANSWER - severe liver disease
- DIC
- hereditary or acquired deficiencies of any factors
- vitamin K
von Willebrand factor - ANSWER - vWF required for platelet adhesion
- performed when platelet function defects are evident
- immunoassays in reference laboratories
Causes of Thrombocytopenia - ANSWER - viral infection
- bacterial infection
, - parasitic infection
- medications like aspirin or acetaminophen
Hemostasis - ANSWER the ability of the body's systems to maintain the integrity of the
blood and blood vessels
Hemostasis involves - ANSWER - a number of complex pathways
- platelets
- coagulation factors
Mechanical phase - ANSWER - initiated when blood vessel is ruptured or torn
- exposed subendothelium of vessel is charged
- platelets are attracted to charged surface
Platelets at charged surface - ANSWER - undergo morphologic and physiologic changes
- causes:
adhere to each other and endothelium once activated expose phosphatidylserine on
their outer membrane.
von Willebrand factor - ANSWER - stabalizes the platelet plug
- large glycoprotein that circulates with F VIII and aids in platelet aggregation at the
beginning of the coagulation pathway
Trigger for chemical phase - ANSWER Adhesion and aggregation of platelets
Coagulation Cascade - ANSWER involves a number of factors both intrinsic and
extrinsic pathways results in a fibrin mesh or clot.
F VII - ANSWER proconvertin
F VIII - ANSWER Antihemophilic factor
F IX - ANSWER Plasma thromboplastin Christmas factor
F XI - ANSWER - plasma
- thromboplastin
- antecedent
F XII - ANSWER Hageman factor
Sample collection for coagulation tests - ANSWER - minimize tissue damage
- minimal venous stasis
