ABSITE - PANCREAS – QUESTIONS WITH
CORRECT ANSWERS 2025
AllNofNtheNfollowingNinheritedNfamilialNsyndromesNareNassociatedNwithNanNincreasedNincidenceNofNpancrea
ticNendocrineNneoplasmsNexcept:
A.NvonNHippel-LindauN(VHL)Nsyndrome.
B.NtuberousNsclerosisN(TSC).
C.NmultipleNendocrineNneoplasiaNtypeN1N(MEN-1).
D.NPeutz-JeghersNsyndromeN(PJS).
E.NneurofibromatosisN(NF-1).N-NCORRECTNANSWERN-Peutz-JeghersNsyndromeN(PJS).
Correct.
TheNmajorityNofNpancreaticNendocrineNneoplasmsNareNsporadic.NSomeNofNthem,Nhowever,NoccurNasNpartNo
fNinheritedNfamilialNsyndromesNsuchNasNMEN-1,NVHLNsyndrome,NNF-1,NandNTSC.NMEN-
1NisNassociatedNwithNgastrinoma,NwhileNNF-
1NisNassociatedNwithNsomatostatinomas.NVHLNandNTSCNareNbothNassociatedNwithNincreasedNpancreaticNen
docrineNneoplasms.NPJSNisNcharacterizedNbyNtheNdevelopmentNofNbenignNhamartomatousNpolypsNinNtheNg
astrointestinalNtract.NItNisNassociatedNwithNanNincreasedNriskNofNdevelopingNcarcinomasNofNtheNpancreas,Nli
ver,Nlungs,Nbreast,Novaries,Nuterus,Ntesticles,NandNotherNorgans.
WhichNofNtheNfollowingNstatementsNisNtrueNregardingNpseudocystsNinNchronicNpancreatitis?
A.NPseudocysts,NalthoughNcommonNfollowingNanNepisodeNofNacuteNpancreatitis,NrarelyNoccurNinNpatientsN
withNchronicNpancreatitis.
B.NRecurrenceNofNaNpancreaticNpseudocystNafterNaspirationNimpliesNanNongoingNcommunicationNwithNtheN
pancreaticNduct.
C.NInNpatientsNwithNchronicNpancreatitisNandNaNpseudocyst,NadequateNdrainageNofNtheNpseudocystNwillNus
uallyNresultNinNsignificantNpainNreliefNandNdecreasedNnarcoticNrequirements.
D.NPercutaneousNdrainageNsuccessfullyNtreatsNpancreaticNpseudocystsNinNnearlyNallNcases.N-
NCORRECTNANSWERN-
RecurrenceNofNaNpancreaticNpseudocystNafterNaspirationNimpliesNanNongoingNcommunicationNwithNtheNpa
ncreaticNduct.
Correct.
, PancreaticNpseudocystsNareNaNcommonNcomplicationNofNchronicNpancreatitis.NTheNunderlyingNductalNabno
rmalitiesNinNpatientsNwithNchronicNpancreatitisNmakeNpseudocystsNlessNlikelyNtoNregressNspontaneouslyNinN
theseNpatients.NPseudocystsNcanNbeNanNimportantNadditionalNcauseNofNpainNinNpatientsNwithNchronicNpanc
reatitis,NbutNtreatmentNofNtheNpseudocystNrarelyNleadsNtoNcompleteNpainNrelief.NIdeally,NtheNpancreaticNdu
ctalNanatomyNshouldNbeNdefinedNpriorNtoNanyNattemptNatNtreatment.NANpseudocystNthatNrecursNafterNperc
utaneousNdrainageNhasNbyNdefinitionNanNongoingNcommunicationNwithNtheNpancreaticNductalNsystemNandN
isNbestNtreatedNbyNoperativeNinternalNdrainage.NThisNprocedureNcanNbeNcombinedNwithNaNductalNdrainageN
procedureNifNindicatedNtoNaddressNtheNpatient'sNchronicNpancreatitis.
AN35-year-
oldNwomanNisNevaluatedNforNaNseizureNdisorder,NmentalNobtundation,NandNpersonalityNchange.NTheNfindin
gsNonNphysicalNexaminationNareNnormal.NTheNfastingNserumNglucoseNisN44Nmg/dL.NOtherNserumNvaluesNare
Nnormal.NAnNinsulin-to-
glucoseN(I:G)NratioNofN0.5NwasNdocumentedNafterN28NhoursNofNfasting.NSymptomsNofNmentalNobtundationN
developedNconcurrentlyNandNwereNreversedNbyNmeansNofNoralNadministrationNofNglucose.NEndoscopicNultr
asonographyNshowedNaN1.2-
cmNmassNinNtheNheadNofNtheNpancreas.NAppropriateNmanagementNconsistsNofNwhichNofNtheNfollowing?
A.NLong-termNadministrationNofNoctreotide
B.NSurgicalNenucleationNofNtheNtumor
C.NPancreaticoduodenectomy
D.NTotalNpancreatectomyN-NCORRECTNANSWERN-SurgicalNenucleationNofNtheNtumor
Correct.
ManagementNofNanNinsulinomaNisNsurgicalNinNnearlyNallNcases.NInsulinomasNareNevenlyNdistributedNinNtheN
pancreas;NapproximatelyNoneNthirdNareNlocatedNinNtheNheadNandNuncinateNprocess,NoneNthirdNinNtheNbody
NofNtheNgland,NandNoneNthirdNinNtheNtailNofNtheNgland.NNinetyNpercentNofNpatientsNhaveNaNbenignNsolitaryNa
denomaNamenableNtoNsurgicalNcure.NSmallNbenignNinsulinomasNnotNcloseNtoNtheNpancreaticNductNcanNbeNr
emovedNbyNmeansNofNenucleation,NindependentNofNlocationNwithinNtheNgland.NInNtheNbodyNandNtailNofNth
eNpancreas,NinsulinomasNlargerNthanN2NcmNinNdiameterNandNthoseNcloseNtoNtheNpancreaticNductNareNmostN
commonlyNexcisedNbyNmeansNofNaNdistalNpancreatectomy.NLargeNinsulinomasNdeepNinNtheNheadNofNpancre
asNorNuncinateNprocessNofNtheNpancreasNmayNnotNbeNamenableNtoNlocalNexcisionNandNmayNnecessitateNpa
ncreaticoduodenectomy.
WhichNofNtheNfollowingNgeneticNalterationsNisNfoundNinNhighNfrequencyN(50%NorNgreater)NinNpatientsNwithN
pancreaticNcancer?
A.N
CORRECT ANSWERS 2025
AllNofNtheNfollowingNinheritedNfamilialNsyndromesNareNassociatedNwithNanNincreasedNincidenceNofNpancrea
ticNendocrineNneoplasmsNexcept:
A.NvonNHippel-LindauN(VHL)Nsyndrome.
B.NtuberousNsclerosisN(TSC).
C.NmultipleNendocrineNneoplasiaNtypeN1N(MEN-1).
D.NPeutz-JeghersNsyndromeN(PJS).
E.NneurofibromatosisN(NF-1).N-NCORRECTNANSWERN-Peutz-JeghersNsyndromeN(PJS).
Correct.
TheNmajorityNofNpancreaticNendocrineNneoplasmsNareNsporadic.NSomeNofNthem,Nhowever,NoccurNasNpartNo
fNinheritedNfamilialNsyndromesNsuchNasNMEN-1,NVHLNsyndrome,NNF-1,NandNTSC.NMEN-
1NisNassociatedNwithNgastrinoma,NwhileNNF-
1NisNassociatedNwithNsomatostatinomas.NVHLNandNTSCNareNbothNassociatedNwithNincreasedNpancreaticNen
docrineNneoplasms.NPJSNisNcharacterizedNbyNtheNdevelopmentNofNbenignNhamartomatousNpolypsNinNtheNg
astrointestinalNtract.NItNisNassociatedNwithNanNincreasedNriskNofNdevelopingNcarcinomasNofNtheNpancreas,Nli
ver,Nlungs,Nbreast,Novaries,Nuterus,Ntesticles,NandNotherNorgans.
WhichNofNtheNfollowingNstatementsNisNtrueNregardingNpseudocystsNinNchronicNpancreatitis?
A.NPseudocysts,NalthoughNcommonNfollowingNanNepisodeNofNacuteNpancreatitis,NrarelyNoccurNinNpatientsN
withNchronicNpancreatitis.
B.NRecurrenceNofNaNpancreaticNpseudocystNafterNaspirationNimpliesNanNongoingNcommunicationNwithNtheN
pancreaticNduct.
C.NInNpatientsNwithNchronicNpancreatitisNandNaNpseudocyst,NadequateNdrainageNofNtheNpseudocystNwillNus
uallyNresultNinNsignificantNpainNreliefNandNdecreasedNnarcoticNrequirements.
D.NPercutaneousNdrainageNsuccessfullyNtreatsNpancreaticNpseudocystsNinNnearlyNallNcases.N-
NCORRECTNANSWERN-
RecurrenceNofNaNpancreaticNpseudocystNafterNaspirationNimpliesNanNongoingNcommunicationNwithNtheNpa
ncreaticNduct.
Correct.
, PancreaticNpseudocystsNareNaNcommonNcomplicationNofNchronicNpancreatitis.NTheNunderlyingNductalNabno
rmalitiesNinNpatientsNwithNchronicNpancreatitisNmakeNpseudocystsNlessNlikelyNtoNregressNspontaneouslyNinN
theseNpatients.NPseudocystsNcanNbeNanNimportantNadditionalNcauseNofNpainNinNpatientsNwithNchronicNpanc
reatitis,NbutNtreatmentNofNtheNpseudocystNrarelyNleadsNtoNcompleteNpainNrelief.NIdeally,NtheNpancreaticNdu
ctalNanatomyNshouldNbeNdefinedNpriorNtoNanyNattemptNatNtreatment.NANpseudocystNthatNrecursNafterNperc
utaneousNdrainageNhasNbyNdefinitionNanNongoingNcommunicationNwithNtheNpancreaticNductalNsystemNandN
isNbestNtreatedNbyNoperativeNinternalNdrainage.NThisNprocedureNcanNbeNcombinedNwithNaNductalNdrainageN
procedureNifNindicatedNtoNaddressNtheNpatient'sNchronicNpancreatitis.
AN35-year-
oldNwomanNisNevaluatedNforNaNseizureNdisorder,NmentalNobtundation,NandNpersonalityNchange.NTheNfindin
gsNonNphysicalNexaminationNareNnormal.NTheNfastingNserumNglucoseNisN44Nmg/dL.NOtherNserumNvaluesNare
Nnormal.NAnNinsulin-to-
glucoseN(I:G)NratioNofN0.5NwasNdocumentedNafterN28NhoursNofNfasting.NSymptomsNofNmentalNobtundationN
developedNconcurrentlyNandNwereNreversedNbyNmeansNofNoralNadministrationNofNglucose.NEndoscopicNultr
asonographyNshowedNaN1.2-
cmNmassNinNtheNheadNofNtheNpancreas.NAppropriateNmanagementNconsistsNofNwhichNofNtheNfollowing?
A.NLong-termNadministrationNofNoctreotide
B.NSurgicalNenucleationNofNtheNtumor
C.NPancreaticoduodenectomy
D.NTotalNpancreatectomyN-NCORRECTNANSWERN-SurgicalNenucleationNofNtheNtumor
Correct.
ManagementNofNanNinsulinomaNisNsurgicalNinNnearlyNallNcases.NInsulinomasNareNevenlyNdistributedNinNtheN
pancreas;NapproximatelyNoneNthirdNareNlocatedNinNtheNheadNandNuncinateNprocess,NoneNthirdNinNtheNbody
NofNtheNgland,NandNoneNthirdNinNtheNtailNofNtheNgland.NNinetyNpercentNofNpatientsNhaveNaNbenignNsolitaryNa
denomaNamenableNtoNsurgicalNcure.NSmallNbenignNinsulinomasNnotNcloseNtoNtheNpancreaticNductNcanNbeNr
emovedNbyNmeansNofNenucleation,NindependentNofNlocationNwithinNtheNgland.NInNtheNbodyNandNtailNofNth
eNpancreas,NinsulinomasNlargerNthanN2NcmNinNdiameterNandNthoseNcloseNtoNtheNpancreaticNductNareNmostN
commonlyNexcisedNbyNmeansNofNaNdistalNpancreatectomy.NLargeNinsulinomasNdeepNinNtheNheadNofNpancre
asNorNuncinateNprocessNofNtheNpancreasNmayNnotNbeNamenableNtoNlocalNexcisionNandNmayNnecessitateNpa
ncreaticoduodenectomy.
WhichNofNtheNfollowingNgeneticNalterationsNisNfoundNinNhighNfrequencyN(50%NorNgreater)NinNpatientsNwithN
pancreaticNcancer?
A.N