BSN 315 - Elimination/GI Questions And Correct Answers
Which of the following conditions is treated with a histamine2 blocker?
Select all that apply.
Gastric carcinoma
Gastric ulcer
Duodenal ulcer
Gastroparesis
Gastroesophageal reflux disease
Gastric ulcer
Histamine2 blockers are effective in the treatment of gastric ulcers.
Duodenal ulcer
Histamine2 blockers are effective in the treatment of duodenal ulcers.
Gastroesophageal reflux disease
Histamine2 blockers are effective in the treatment of gastroesophageal reflux disease.
Which of the following statements regarding the pharmacodynamics of cimetidine is
true?Cimetidine has an onset of action of 15 minutes.
,Cimetidine's duration of action is 8 to 12 hours.
It reaches its peak in 2 to 3 hours.
The elimination half-life is 1.5 to 2 hours for cimetidine.
The elimination half-life is 1.5 to 2 hours for cimetidine.
Rationale for Incorrect:
The onset of action of cimetidine is approximately 30 minutes, not 15 minutes after
administration.
The duration of action of this medication is 4 to 5 hours, not 8 to 12 hours. It is dosed
three to four times daily.
Cimetidine peaks in 45 to 90 minutes, not 2 to 3 hours.
Which of the following statements is true regarding the pharmacokinetics of cimetidine?
Food enhances the absorption of cimetidine.
Cimetidine readily crosses the blood-brain barrier.
Cimetidine is primarily excreted in the urine.
The drug does not undergo hepatic metabolism.
,Cimetidine is primarily excreted in the urine.
This histamine2 receptor antagonist is primarily excreted in the urine. Accumulation of
the drug may occur in patients with renal impairment.
Rationale for Incorrect:
Food delays, rather than enhances, the absorption of cimetidine; however, the overall
effect of cimetidine is not affected.
Cimetidine does not readily cross the blood-brain barrier.
Cimetidine does undergo hepatic metabolism.
With which of the following instructions would the nurse instruct Mr. Evans regarding
the timing of the prescribed cimetidine?
Case Study Details
Mr. Evans is a 47-year-old male patient who came to the clinic and stated he had an
upset stomach and heartburn. He states these symptoms have occurred over a couple
of weeks and that over-the-counter therapy has not helped resolve the issue. Mr. Evans
says he takes antacids daily. By physical assessment, the nurse finds Mr. Evans is
stable and his vital signs all within normal limits. After assessing Mr. Evans, the health
care provider prescribes cimetidine. Because Mr. Evans has not taken cimetidine
before, the nurse needs to teach him about his new medication.
Before meals and at bedtime.
, Before meals and in the morning after arising
After meals and in the morning after arising
After meals and at bedtime
Before meals and at bedtime.
Histamine2 receptor antagonists, such as cimetidine are to be taken just before meals
and at bedtime to decrease food-induced acid secretion.
Before administering cimetidine to a 27-year-old female patient, which patient
parameter would a nurse ensure has been evaluated?
Select all that apply.
Hepatic function
Renal function
Thyroid function
Pregnancy status
Fluid and electrolyte status
Hepatic function
The patient's liver function should be evaluated before the administration of cimetidine.
Renal function
The patient's renal function should be evaluated before the administration of cimetidine.
Pregnancy status
Pregnancy status should be assessed on this female client of childbearing age before
Which of the following conditions is treated with a histamine2 blocker?
Select all that apply.
Gastric carcinoma
Gastric ulcer
Duodenal ulcer
Gastroparesis
Gastroesophageal reflux disease
Gastric ulcer
Histamine2 blockers are effective in the treatment of gastric ulcers.
Duodenal ulcer
Histamine2 blockers are effective in the treatment of duodenal ulcers.
Gastroesophageal reflux disease
Histamine2 blockers are effective in the treatment of gastroesophageal reflux disease.
Which of the following statements regarding the pharmacodynamics of cimetidine is
true?Cimetidine has an onset of action of 15 minutes.
,Cimetidine's duration of action is 8 to 12 hours.
It reaches its peak in 2 to 3 hours.
The elimination half-life is 1.5 to 2 hours for cimetidine.
The elimination half-life is 1.5 to 2 hours for cimetidine.
Rationale for Incorrect:
The onset of action of cimetidine is approximately 30 minutes, not 15 minutes after
administration.
The duration of action of this medication is 4 to 5 hours, not 8 to 12 hours. It is dosed
three to four times daily.
Cimetidine peaks in 45 to 90 minutes, not 2 to 3 hours.
Which of the following statements is true regarding the pharmacokinetics of cimetidine?
Food enhances the absorption of cimetidine.
Cimetidine readily crosses the blood-brain barrier.
Cimetidine is primarily excreted in the urine.
The drug does not undergo hepatic metabolism.
,Cimetidine is primarily excreted in the urine.
This histamine2 receptor antagonist is primarily excreted in the urine. Accumulation of
the drug may occur in patients with renal impairment.
Rationale for Incorrect:
Food delays, rather than enhances, the absorption of cimetidine; however, the overall
effect of cimetidine is not affected.
Cimetidine does not readily cross the blood-brain barrier.
Cimetidine does undergo hepatic metabolism.
With which of the following instructions would the nurse instruct Mr. Evans regarding
the timing of the prescribed cimetidine?
Case Study Details
Mr. Evans is a 47-year-old male patient who came to the clinic and stated he had an
upset stomach and heartburn. He states these symptoms have occurred over a couple
of weeks and that over-the-counter therapy has not helped resolve the issue. Mr. Evans
says he takes antacids daily. By physical assessment, the nurse finds Mr. Evans is
stable and his vital signs all within normal limits. After assessing Mr. Evans, the health
care provider prescribes cimetidine. Because Mr. Evans has not taken cimetidine
before, the nurse needs to teach him about his new medication.
Before meals and at bedtime.
, Before meals and in the morning after arising
After meals and in the morning after arising
After meals and at bedtime
Before meals and at bedtime.
Histamine2 receptor antagonists, such as cimetidine are to be taken just before meals
and at bedtime to decrease food-induced acid secretion.
Before administering cimetidine to a 27-year-old female patient, which patient
parameter would a nurse ensure has been evaluated?
Select all that apply.
Hepatic function
Renal function
Thyroid function
Pregnancy status
Fluid and electrolyte status
Hepatic function
The patient's liver function should be evaluated before the administration of cimetidine.
Renal function
The patient's renal function should be evaluated before the administration of cimetidine.
Pregnancy status
Pregnancy status should be assessed on this female client of childbearing age before
