CPHON Study Guide ACTUAL Exam
Questions and CORRECT Answers
What does Hydroxyurea stimulate? - CORRECT ANSWER - fetal hgb
What is Rituximab? - CORRECT ANSWER - Monoclonal antibody
acts against CD20
used for Burkitts Lymphoma
Where is erythropoietin produced? - CORRECT ANSWER - kidneys
epryhropoietin: regulates and controls the production of maturation of RBCs
What is Septra and Dapsone for? - CORRECT ANSWER - to prevent pneumocystis
jiroveci.
What can Septra (Bactrim) cause? - CORRECT ANSWER - bone marrow suppression
Imatinib is best treatment for.... - CORRECT ANSWER - CML
What can Tacrolimus cause? - CORRECT ANSWER - reversible posterior encephalopathy
Dactinomycin can cause? - CORRECT ANSWER - radiation recall
Bleomycin can cause? - CORRECT ANSWER - pulmonary fibrosis. Make sure to tell
anesthesia before being put to sleep. You cannot hyper oxygenate bc it will make it worse.
What chemos have a max dose? - CORRECT ANSWER - Bleomycin
,Doxorubicin 550mg/m2
What can Asparaginase cause? - CORRECT ANSWER - Pancreatitis and High blood
sugar
What can VP16 cause? - CORRECT ANSWER - secondary AML
Alkylating agents are responsible for... - CORRECT ANSWER - fertility issues. Think of
transplant chemos and high dose chemos like cisplatin, ifosphamide
What is the first line of treatment for hemolytic anemia? - CORRECT ANSWER - Steroids
What drug is given for iron overload? - CORRECT ANSWER - Deferoxamine it is a
chelating agent
Most common childhood cancer? - CORRECT ANSWER - ALL
Most common solid tumor cancer? - CORRECT ANSWER - Brain tumors
Astrocytoma: most common brain tumor
Medulloblastoma: most common malignant brain tumor
Most common extracranial solid tumor? - CORRECT ANSWER - NB
Alkylating Agents.... - CORRECT ANSWER - interrupts the cell cycle
cytoxan (cycle)
Ifosfamide
Lomustine
Carmustine
,Buslfan
Procarbazine
Temozolimide
Decarbazine
Cisplatin
Carboplatin
Antitumor Antiboitics.... - CORRECT ANSWER - interfere with cell metabolism
Dactinomycin
Bleomycin
Daunorubicin
Doxorubicin
Idarubicin
Antimetabolites.... - CORRECT ANSWER - Stops the ability at the nucleus
5FU
6MP
Gemcitabine
Fludarabine
Cytrarbine
Hydroxyurea
Methotrexate
Plant Alkaloids.... - CORRECT ANSWER - cause DNA breakdown
VP16
Paclitaxel
Docetaxel
Topotecan
, Irinotecan
Vincristine:max single dose 2mg
Vinblastine
Vinorelbine
Miscellaneous... - CORRECT ANSWER - mechanisms not understood
Asparaginase
Retinoids
Imatinib (Gleevac)
Ambisome - CORRECT ANSWER - antifungal
check K
think about pt on antibiotics for 1 week and still having F/N think fungal
What are Biologic Response Modifiers (BRM)? - CORRECT ANSWER - attack targeted
pathways and tumor receptor sites
What scan is gold standard with NB? - CORRECT ANSWER - MIBG
What is Flagyl used for? - CORRECT ANSWER - Cdiff
Tacrolimus side effects? - CORRECT ANSWER - Hypomagnesium
Hearling loss
Dizzy
What does Mag sulfate prevent with Cisplatin? - CORRECT ANSWER - leg cramps
Questions and CORRECT Answers
What does Hydroxyurea stimulate? - CORRECT ANSWER - fetal hgb
What is Rituximab? - CORRECT ANSWER - Monoclonal antibody
acts against CD20
used for Burkitts Lymphoma
Where is erythropoietin produced? - CORRECT ANSWER - kidneys
epryhropoietin: regulates and controls the production of maturation of RBCs
What is Septra and Dapsone for? - CORRECT ANSWER - to prevent pneumocystis
jiroveci.
What can Septra (Bactrim) cause? - CORRECT ANSWER - bone marrow suppression
Imatinib is best treatment for.... - CORRECT ANSWER - CML
What can Tacrolimus cause? - CORRECT ANSWER - reversible posterior encephalopathy
Dactinomycin can cause? - CORRECT ANSWER - radiation recall
Bleomycin can cause? - CORRECT ANSWER - pulmonary fibrosis. Make sure to tell
anesthesia before being put to sleep. You cannot hyper oxygenate bc it will make it worse.
What chemos have a max dose? - CORRECT ANSWER - Bleomycin
,Doxorubicin 550mg/m2
What can Asparaginase cause? - CORRECT ANSWER - Pancreatitis and High blood
sugar
What can VP16 cause? - CORRECT ANSWER - secondary AML
Alkylating agents are responsible for... - CORRECT ANSWER - fertility issues. Think of
transplant chemos and high dose chemos like cisplatin, ifosphamide
What is the first line of treatment for hemolytic anemia? - CORRECT ANSWER - Steroids
What drug is given for iron overload? - CORRECT ANSWER - Deferoxamine it is a
chelating agent
Most common childhood cancer? - CORRECT ANSWER - ALL
Most common solid tumor cancer? - CORRECT ANSWER - Brain tumors
Astrocytoma: most common brain tumor
Medulloblastoma: most common malignant brain tumor
Most common extracranial solid tumor? - CORRECT ANSWER - NB
Alkylating Agents.... - CORRECT ANSWER - interrupts the cell cycle
cytoxan (cycle)
Ifosfamide
Lomustine
Carmustine
,Buslfan
Procarbazine
Temozolimide
Decarbazine
Cisplatin
Carboplatin
Antitumor Antiboitics.... - CORRECT ANSWER - interfere with cell metabolism
Dactinomycin
Bleomycin
Daunorubicin
Doxorubicin
Idarubicin
Antimetabolites.... - CORRECT ANSWER - Stops the ability at the nucleus
5FU
6MP
Gemcitabine
Fludarabine
Cytrarbine
Hydroxyurea
Methotrexate
Plant Alkaloids.... - CORRECT ANSWER - cause DNA breakdown
VP16
Paclitaxel
Docetaxel
Topotecan
, Irinotecan
Vincristine:max single dose 2mg
Vinblastine
Vinorelbine
Miscellaneous... - CORRECT ANSWER - mechanisms not understood
Asparaginase
Retinoids
Imatinib (Gleevac)
Ambisome - CORRECT ANSWER - antifungal
check K
think about pt on antibiotics for 1 week and still having F/N think fungal
What are Biologic Response Modifiers (BRM)? - CORRECT ANSWER - attack targeted
pathways and tumor receptor sites
What scan is gold standard with NB? - CORRECT ANSWER - MIBG
What is Flagyl used for? - CORRECT ANSWER - Cdiff
Tacrolimus side effects? - CORRECT ANSWER - Hypomagnesium
Hearling loss
Dizzy
What does Mag sulfate prevent with Cisplatin? - CORRECT ANSWER - leg cramps
