CPHON-Hematology UPDATED ACTUAL
Exam Questions and CORRECT
Answers
Bone Marrow Failure: examples of - CORRECT ANSWER - Autoimmune hemolytic
anemia, fanconi's anemia, dyskeratosis congentia, shwachman-diamond syndrome
Platelet/ coagulation diseases - CORRECT ANSWER - ITP, Thrombosis, thrombophilia,
hemophilia, VWD
RBC disease: examples - CORRECT ANSWER - SCD, thalassemia, Glucose 6-phosphate
dehydrogenase deficiency, heredity spherocytosis
A child with dysmorphic thumbs is newly dx with myelodyplastic syndrome. What does the RN
anticipate an additional evaluation for? - CORRECT ANSWER - Fanconi Anemia
Von Willebrand is missing... - CORRECT ANSWER - V, W factor
Iron def & Thalassemia: What are the lab differences between them - CORRECT
ANSWER - Iron def- Fe & ferritin levels are low
Thalassemia- Fe & ferritin levels are both normal to high
3 Factors that increase risk of thromboembolism - CORRECT ANSWER - Factor V
Leiden
Protein C & S deficiency
Protein C & S act as Vitamin K dependent proteins which are anticoagulants
,Thalassemia : How does it gets transmitted genetically? - CORRECT ANSWER - B-Thal
= autosomal recessive
SCD: What is the main symptom of spleenic infarction with SCD disease? - CORRECT
ANSWER - ULQ pain, severe
Pneumocystis Pneumonia: The causative organism of - CORRECT ANSWER - A Fungus
Amylase & lipase : what are they - CORRECT ANSWER - Amylase- breakdown starches
Lipase- digest fats
What electrolytes have an inverse relationship with each other? - CORRECT ANSWER -
potassium - magnesium
Phosphate-calcium
Sodium-water
PTT-fibrinogen
B cells purpose - CORRECT ANSWER - Humoral immunity- makes antibodies, memory
cells
Eosinophils: purpose - CORRECT ANSWER - Prominent in allergic rxs
Can selectively destroy parasites/ have function in immediate allergic/hypersensitivity reactions/
produced prifivrinolysin - form fubrinolysin - digests fibrin- dissolves clots
Stem cells mature into - CORRECT ANSWER - RBC, granulocytes, monocytes,
lymphocytes, plts
,Monocytes purpose - CORRECT ANSWER - Phagocytosis
Large phagocytic cells involved in early stage of inflammatory reaction
natural killer cells (NK cells) purpose - CORRECT ANSWER - Destroy viruses &
malignant cells non specifically
Neutrophils purpose - CORRECT ANSWER - Ingest & destroy microorganisms, primary
defense against bacterial infections
Primary defense in infection/phagocytize and kill bacteria
T lymphocytes (T cells) purpose - CORRECT ANSWER - Cell mediated immunity-
attacks invaders
a lymphocyte
They are circulated through the thymus gland- ralidly- divide & produce T-cells that are
sensituzed to antigen-killer cells- play a role in body's resistance to proliferation of cancer cells
Malignant stem cells are - CORRECT ANSWER - Cells that lose the ability to regulate
cell division and differentiate to mature functioning cells
Blasts accumulate where and what does this cause - CORRECT ANSWER - Marrow
spaces, peripheral vasculature, and organs
Normal cell proliferation is blocked d/t lack of space/nutrients
Diploid - CORRECT ANSWER - 46 chromosomes
G6PD: A ______ retic count and _____Coombs test are found in glucose 6 phosphate deficiency
- CORRECT ANSWER - High; negative
, Pseudodiploid - CORRECT ANSWER - 46 chromosomes with structural changes
Hyperdiploidy and prognosis - CORRECT ANSWER - Fewer than 50 chromosomes and
good prognosis
Platelet life span - CORRECT ANSWER - 7-10 days
Lymphocytes - CORRECT ANSWER - Involved in development of antibodies and
delayed hypersensitivity
RBC lifespan - CORRECT ANSWER - 120 days (4 months)
Hemoglobin is broken down into - CORRECT ANSWER - Iron- iron is used by bone
marrow to make more RBC and bilirubin which is excreted by liver as bile
Erythopoietin: What happens when it is released into the bloodstream - CORRECT
ANSWER - It stimulates the bone marrow to make new RBCs
Basophils - CORRECT ANSWER - Healing phase of inflammation- become mast cells on
tissue- responsible for histamine release- allows WBCs to exit vessels at site of injury
Erythropoietin is produced by _____in response to_____ - CORRECT ANSWER -
Kidneys
Tissue Hypoxia
Platelets decrease after chemo - CORRECT ANSWER - 7-21 days
Cancer cell deviations - CORRECT ANSWER - No present number of divisions before
death
Exam Questions and CORRECT
Answers
Bone Marrow Failure: examples of - CORRECT ANSWER - Autoimmune hemolytic
anemia, fanconi's anemia, dyskeratosis congentia, shwachman-diamond syndrome
Platelet/ coagulation diseases - CORRECT ANSWER - ITP, Thrombosis, thrombophilia,
hemophilia, VWD
RBC disease: examples - CORRECT ANSWER - SCD, thalassemia, Glucose 6-phosphate
dehydrogenase deficiency, heredity spherocytosis
A child with dysmorphic thumbs is newly dx with myelodyplastic syndrome. What does the RN
anticipate an additional evaluation for? - CORRECT ANSWER - Fanconi Anemia
Von Willebrand is missing... - CORRECT ANSWER - V, W factor
Iron def & Thalassemia: What are the lab differences between them - CORRECT
ANSWER - Iron def- Fe & ferritin levels are low
Thalassemia- Fe & ferritin levels are both normal to high
3 Factors that increase risk of thromboembolism - CORRECT ANSWER - Factor V
Leiden
Protein C & S deficiency
Protein C & S act as Vitamin K dependent proteins which are anticoagulants
,Thalassemia : How does it gets transmitted genetically? - CORRECT ANSWER - B-Thal
= autosomal recessive
SCD: What is the main symptom of spleenic infarction with SCD disease? - CORRECT
ANSWER - ULQ pain, severe
Pneumocystis Pneumonia: The causative organism of - CORRECT ANSWER - A Fungus
Amylase & lipase : what are they - CORRECT ANSWER - Amylase- breakdown starches
Lipase- digest fats
What electrolytes have an inverse relationship with each other? - CORRECT ANSWER -
potassium - magnesium
Phosphate-calcium
Sodium-water
PTT-fibrinogen
B cells purpose - CORRECT ANSWER - Humoral immunity- makes antibodies, memory
cells
Eosinophils: purpose - CORRECT ANSWER - Prominent in allergic rxs
Can selectively destroy parasites/ have function in immediate allergic/hypersensitivity reactions/
produced prifivrinolysin - form fubrinolysin - digests fibrin- dissolves clots
Stem cells mature into - CORRECT ANSWER - RBC, granulocytes, monocytes,
lymphocytes, plts
,Monocytes purpose - CORRECT ANSWER - Phagocytosis
Large phagocytic cells involved in early stage of inflammatory reaction
natural killer cells (NK cells) purpose - CORRECT ANSWER - Destroy viruses &
malignant cells non specifically
Neutrophils purpose - CORRECT ANSWER - Ingest & destroy microorganisms, primary
defense against bacterial infections
Primary defense in infection/phagocytize and kill bacteria
T lymphocytes (T cells) purpose - CORRECT ANSWER - Cell mediated immunity-
attacks invaders
a lymphocyte
They are circulated through the thymus gland- ralidly- divide & produce T-cells that are
sensituzed to antigen-killer cells- play a role in body's resistance to proliferation of cancer cells
Malignant stem cells are - CORRECT ANSWER - Cells that lose the ability to regulate
cell division and differentiate to mature functioning cells
Blasts accumulate where and what does this cause - CORRECT ANSWER - Marrow
spaces, peripheral vasculature, and organs
Normal cell proliferation is blocked d/t lack of space/nutrients
Diploid - CORRECT ANSWER - 46 chromosomes
G6PD: A ______ retic count and _____Coombs test are found in glucose 6 phosphate deficiency
- CORRECT ANSWER - High; negative
, Pseudodiploid - CORRECT ANSWER - 46 chromosomes with structural changes
Hyperdiploidy and prognosis - CORRECT ANSWER - Fewer than 50 chromosomes and
good prognosis
Platelet life span - CORRECT ANSWER - 7-10 days
Lymphocytes - CORRECT ANSWER - Involved in development of antibodies and
delayed hypersensitivity
RBC lifespan - CORRECT ANSWER - 120 days (4 months)
Hemoglobin is broken down into - CORRECT ANSWER - Iron- iron is used by bone
marrow to make more RBC and bilirubin which is excreted by liver as bile
Erythopoietin: What happens when it is released into the bloodstream - CORRECT
ANSWER - It stimulates the bone marrow to make new RBCs
Basophils - CORRECT ANSWER - Healing phase of inflammation- become mast cells on
tissue- responsible for histamine release- allows WBCs to exit vessels at site of injury
Erythropoietin is produced by _____in response to_____ - CORRECT ANSWER -
Kidneys
Tissue Hypoxia
Platelets decrease after chemo - CORRECT ANSWER - 7-21 days
Cancer cell deviations - CORRECT ANSWER - No present number of divisions before
death
