Carbamazepine (Tegretol) can sometimes show subtherapeutic range due to what? - Answers
Carbamazepine auto-induces metabolism, leading to lower levels despite good compliance
What are the black box warnings for Carbamazepine? - Answers Dermatologic reactions
1. Steven's Johnson
2. Toxic epidermal necrolysis
What lab test should be ordered for patients on Carbamazepine? - Answers CBC every 3-4 months
because it can cause decreased WBC, decreased platelets, and trouble with RBC
What kind of teaching needs to be done with families of patients who have seizure disorders? - Answers
Prevention is important, patient safety is important, Do NOT abruptly stop taking medication.
Ethosuximide (Zarontin), an anti-seizure medication can cause what? - Answers Blood dyscrasias
Patients taking Topiramate need to be monitored for what electrolyte imbalance? - Answers Decreased
sodium bicarb leading to hyperchloremic metabolic acidosis
Topiramate treats seizures and what is one common side effect? - Answers Normal side effect is weight
loss, especially in higher dose patients
A child on Topiramate that wants to play sports should monitor what? - Answers Don't get overheated.
Topiramate may affect his ability to sweat in the heat.
What should a pregnant patient be told about taking Valproate (Depakote)? - Answers It is a known
teratogen and category X medication. It should not be used in the first trimester, it may be restarted in
second trimester.
What patient population should tricyclic antidepressants be used cautiously in? - Answers Heart Disease
patients
Phenelzine (Nardil) is a MAOI. What teaching needs to be done with this medication? - Answers He
should not use serotonergic drugs like Imitrex. Also, this class of medication interacts with yogurt, sour
cream, soy sauce, etc.
Phenelzine (Nardil) may cause what if there is an interaction with known contraindicated foods? -
Answers Hypertensive crisis
What are the side effects of tricyclic antidepressants? - Answers Anticholinergic type effects like dry
mouth, sedation, constipation, increased appetite, blurred vision, tinnitus, euphoria, mania
How long does it take for SSRIs to take effect - Answers 2-6 weeks
, SSRIs may cause what onset of action symptoms? - Answers Nausea, but this will usually resolve in a
week.
What is one thing you should not do with SSRIs? - Answers Drink alcohol
What should happen when going off an SSRI? - Answers Wean slowly, do not stop abruptly
What medications would a patient with depression and anxiety respond well to? - Answers Buspar and
an SSRI combined
Celexa (Citalopram)
Lexapro (Escitalopram)
Why should you combine an SSRI with Buspar? - Answers Buspar augments the SSRI and is a good
combo for anxiety and depression
What is a first line drug for mild to moderate generalized anxiety disorder? - Answers Buspirone
How fast does Celexa start to demonstrate effects? - Answers Improved appetitie and concentration in
1-2 weeks.
What is a major drug to treat bipolar disease? - Answers Lithium
Blood levels need to be monitored with Lithium because why? - Answers Lithium has a narrow
therapeutic range so it is important to recognize toxicity
What are symptoms of lithium toxicity? - Answers Drowsiness and Nausea
What dietary teaching needs to be done with patients taking lithium? - Answers Salt intake needs to be
consistent
What are the side effects of SSRIs (selective seratonin reuptake inhibitor)? - Answers N/V, dizziness, light
headedness, dry mouth, increased sweating, weight changes, agitation, sexual side effects.
What are the side effects of SNRIs (serotonin norepinephrine reuptake inhibitor) - Answers Headache,
somnolence, dizziness, insomnia, nervousness, dry mouth, constipation, abnormal ejaculation,
anorexia/weight loss, elevated BP
What are the side effects of MAOIs? - Answers Insomnia, anxiety, agitation, dizziness, headache,
restlessness, hypotension, dry mouth, blurred vision, constipation
What Benzo has the greatest likelihood of dependence? - Answers Xanax /alprazolam
What receptors do Benzos act on? - Answers Enhances the neurotransmitter GABA (gamma-
aminobutyric acid) receptors
What result do Benzos have on the body? - Answers sedative