Fraction of kids in US that are overweight or obese - Answers ~1/3
Healthy weight percentile range - Answers 5th-85th
Overweight weight percentile range - Answers 85th-95th
Obese weight percentile range - Answers >95th
Vd change for lipophilic drugs in obesity - Answers increases
Vd change for hydrophilic drugs in obesity - Answers increase or decrease
Hepatic clearance change in obesity - Answers decreases (fatty infiltrates in liver)
Renal clearance change in obesity - Answers increases (greater glomerular filtration rate)
Frequency change for renally-eliminated drugs in obesity? - Answers increase frequency
Most commonly reported medication error in pediatrics - Answers incorrect dosage
General dosing recommendation for children? - Answers use weight-based if <18 years, unless ≥ 40 kg
and adult dosing exceeded
Type of weight to use for Vd in obese children - Answers TBW
Type of weight to use for Cl in obese children - Answers lean body weight
Type of weight to use for loading dose of hydrophilic drug in obese children - Answers IBW
Type of weight to use for loading dose of lipophilic drug in obese children - Answers TBW
Type of weight to use for loading dose of partially-lipophilic drug in obese children - Answers AdjBW
Type of weight to use for maintenance doses for obese children - Answers lean body weight
Type of dosing to use for chemo agents for obese children - Answers BSA
Type of weight to use for Vancomycin dosing for obese children - Answers TBW
Type of weight to use for Aminoglycoside dosing for obese children - Answers TBW or AdjBW
BMI equation - Answers weight (kg) / height (m^2)
Ideal body weight equation - Answers 45.5kg (women) or 50 kg (men) + 2.3kg(each inch over 5 feet)
Adjusted body weight equation - Answers AdjBW= IBW + 0.4 (TBW-IBW)
, Term for inflammation of pharynx & surrounding tissues cause by viral, bacterial, or fungal infection -
Answers pharyngitis
Pharyngitis complications most commonly associated with what bacteria? - Answers Streptococcus
pyogenes
Non-supportive pharyngitis complications - Answers acute rheumatic fever, glomerulonephritis,
pediatric autoimmune neuropsychiatric disorder
Most serious strep pyogenes complication - Answers rheumatic heart disease (& rheumatic fever)
Supportive pharyngitis complications - Answers peritonsillar abscess, septic jugular-vein
thrombophlebitis, vincent angina
Common viral pharyngitis organisms: - Answers rhinovirus, adenovirus, coronavirus, epstein-barr virus
(EBV)
Common bacterial pharyngitis organisms: - Answers streptococcus pyogenes, H. flu, chlamydophila
pneumoniae, mycoplasma pneumoniae, neisseria gonorrhoeae
Common fungal pharyngitis organisms: - Answers candida albicans
Common pharyngitis symptoms between viral/bacterial/fungal: - Answers sore throat, painful
swallowing, & fever (peaking day 3-5, resolving by day 10)
Pharyngitis symptoms specific to viruses? - Answers cough, rhinorrhea, tonsillar hypertrophy,
oropharyngeal erythema or edema, cobblestoning, diarrhea, conjunctivitis
Pharyngitis symptoms specific to streptococcal bacteria? - Answers palatal petechiae, tonsillar exudate,
arthralgia or myalgia, cervical adenoapthy, nausea/vomiting, headache
Pharyngitis symptoms specific to fungal infections? - Answers oropharygeal curd-like plaques or smooth
red patches, loss of taste or mouth numbness
What information do throat cultures provide for pharyngitis? - Answers rules-out atypical (non-GAS) or
fungal infections
What information do rapid antigen detection tests (RADT) provide for pharyngitis? - Answers rules-in
GAS or respiratory virus infections
Does a negative RADT rule-out non-GAS bacterial pharyngitis? - Answers no
What to do if a patient 5-15 years old gets a negative RADT result? - Answers verify with throat culture
Test used if suspected GAS pharyngitis complication? - Answers Antistreptolysin O titre
Test used if suspected EBV pharyngitis infection? - Answers Mononucleis spot testing