_______ is a group of disorders marked by withdrawal from reality, illogical thinking, hallucinations,
delusions, and emotional and behavioral disturbances. - Answers schizophrenia
Schizophrenia is a devastating illness which causes a schizo, or ______ between a person's emotions,
behaviors and cognitions - Answers split
A patient with a first degree relative with schizophrenia has a (#) time risk of developing schizophrenia -
Answers 10
T/F People who have schizophrenia are more likely to be born in the summer - Answers false (winter or
early spring - Jan - april)
Which of the following is false regarding epidemiology of schizophrenia?
A) more prevalent in urban areas
B) more prevalent in NE and western US
C) associated with higher mortality rate
D) more common in men vs women
E) there is a greater risk of developing schizophrenia if born of father >60 years of age - Answers D (more
common in men vs women - no gender preference)
Approximately (#)% of patients with schizophrenia attempt suicide - Answers 50(%) (10-15% of patients
complete suicide)
Suicide is more common in the first (#) years of the illness - Answers 10
Schizophrenia is related to an excess of:
A) serotonin
B) dopamine
C) norepinephrine - Answers B (dopamine) (however, Current hypotheses posit serotonin excess as a
cause of both positive and negative symptoms in schizophrenia. The robust serotonin antagonist activity
of clozapine and other second-generation antipsychotics coupled with the effectiveness of clozapine to
decrease positive symptoms in chronic patients has contributed to the validity of this proposition)
Delusions, hallucinations, hostility, and disorganized thinking are considered (positive / negative)
symptoms of schizophrenia - Answers positive
, Blunted or manic affect, impairment in associations between thoughts and actions, autism, and
ambivalence are considered (positive / negative) symptoms of schizophrenia - Answers negative (deficits
in behavior | 4 A's)
T/F The majority of schizophrenic patients smoke - Answers true (75% - Smoking is associated with an
increased rate of metabolism of the antipsychotic drugs and a decrease in drug related parkinsonism)
T/F Smoking may decrease positive symptoms in schizophrenia - Answers true
What are the two most commonly abused substances in schizophrenia?
A) cannabis
B) heroin
C) cocaine
D) LSD - Answers A (cannabis)
C (cocaine)
Substance use is associated with a (good / poor) prognosis in schizophrenia - Answers poor
15-45% of which population is diagnosed with schizophrenia?
A) elderly
B) children
C) homeless
D) institutionalized - Answers C (homeless)
T/F The cost of treating schizophrenia exceeds that of all combined cancers - Answers true (estimated 50
billion annually)
The concordance rate for monozygotic twins in schizophrenia is approximately (#)% - Answers 50(%) (It
is 15% in dizygotic twins)
The dopamine theory of schizophrenia posits that schizophrenia results from too (much / little)
dopaminergic activity - Answers much (based off the efficacy in antipsychotics which block dopamine
receptors and in drugs that increase the amount of dopamine causing psychosis -- such as
amphetamines and cocaine)
All of the following are seen in schizophrenia, EXCEPT:
A) Enlargement of the lateral and third ventricles
B) Reduced symmetry in the temporal, frontal, and occipital lobes