PATHOPHYSIOLOGY EXAM 1 2024-2025
QUESTIONS AND ANSWERS.
An ordered photographic display of a set of chromosomes
from a single cell is a(n):
A) metaphase spread.
B) autosomal spread.
C) karyotype.
D) anaphase spread. - ANSWER -c
An error in which homologous chromosomes fail to separate
during meiosis is termed:
A) aneuploidy.
B) nondisjunction.
C) polyploidy.
,D) anaplasia. - ANSWER -b
A somatic cell that does not contain a multiple of 23
chromosomes is called:
A) an aneuploid cell.
B) a euploid cell.
C) a polyploidy cell.
D) a haploid cell. - ANSWER -a
A 20-year-old pregnant female gives birth to a stillborn child.
Autopsy reveals that the fetus has 92 chromosomes. Which
of the following describes this condition?
A) Euploidy
B) Triploidy
C) Tetraploidy
D) Aneuploidy - ANSWER -c
If a person is a chromosomal mosaic, the person may:
,A) be a carrier of the genetic disease.
B) have a mild form of the genetic disease.
C) have two genetic diseases.
D) be sterile as a result of the genetic disease. - ANSWER -b
The most common cause of Down syndrome is:
A) paternal nondisjunction.
B) maternal translocations.
C) maternal nondisjunction.
D) paternal translocations. - ANSWER -c
Risk factors for Down syndrome include:
A) fetal exposure to mutagens in the uterus.
B) increased paternal age.
C) family history of Down syndrome.
D) pregnancy in women over age 35. - ANSWER -d
, A 13-year-old girl has a karyotype that reveals an absent
homologous X chromosome with only a single X
chromosome present. Her condition is called:
A) Down syndrome.
B) Cri du chat syndrome.
C) Turner syndrome.
D) Edward syndrome - ANSWER -c
A child is diagnosed with cystic fibrosis. History reveals that
the child's parents are first cousins. Cystic fibrosis was most
likely the result of:
A) X inactivation.
B) genomic imprinting.
C) consanguinity.
D) obligate carriers. - ANSWER -c
Joey, age 9, is admitted to a pediatric unit with Duchenne
muscular dystrophy. He inherited this condition through a:
QUESTIONS AND ANSWERS.
An ordered photographic display of a set of chromosomes
from a single cell is a(n):
A) metaphase spread.
B) autosomal spread.
C) karyotype.
D) anaphase spread. - ANSWER -c
An error in which homologous chromosomes fail to separate
during meiosis is termed:
A) aneuploidy.
B) nondisjunction.
C) polyploidy.
,D) anaplasia. - ANSWER -b
A somatic cell that does not contain a multiple of 23
chromosomes is called:
A) an aneuploid cell.
B) a euploid cell.
C) a polyploidy cell.
D) a haploid cell. - ANSWER -a
A 20-year-old pregnant female gives birth to a stillborn child.
Autopsy reveals that the fetus has 92 chromosomes. Which
of the following describes this condition?
A) Euploidy
B) Triploidy
C) Tetraploidy
D) Aneuploidy - ANSWER -c
If a person is a chromosomal mosaic, the person may:
,A) be a carrier of the genetic disease.
B) have a mild form of the genetic disease.
C) have two genetic diseases.
D) be sterile as a result of the genetic disease. - ANSWER -b
The most common cause of Down syndrome is:
A) paternal nondisjunction.
B) maternal translocations.
C) maternal nondisjunction.
D) paternal translocations. - ANSWER -c
Risk factors for Down syndrome include:
A) fetal exposure to mutagens in the uterus.
B) increased paternal age.
C) family history of Down syndrome.
D) pregnancy in women over age 35. - ANSWER -d
, A 13-year-old girl has a karyotype that reveals an absent
homologous X chromosome with only a single X
chromosome present. Her condition is called:
A) Down syndrome.
B) Cri du chat syndrome.
C) Turner syndrome.
D) Edward syndrome - ANSWER -c
A child is diagnosed with cystic fibrosis. History reveals that
the child's parents are first cousins. Cystic fibrosis was most
likely the result of:
A) X inactivation.
B) genomic imprinting.
C) consanguinity.
D) obligate carriers. - ANSWER -c
Joey, age 9, is admitted to a pediatric unit with Duchenne
muscular dystrophy. He inherited this condition through a:
