Medication Information Table
Loop Diuretics – furosemide
Category Information
THERAPEUTIC USE • Treats pulmonary edema in heart failure
• Treats edema caused by renal, hepatic, or cardiac failure not affected by
other diuretics
• Treats hypertension not controlled by other diuretics
ADVERSE DRUG • Electrolyte imbalance: hyponatremia, hypochloremia, severe fluid loss
REACTIONS (dehydration), and hypokalemia
• Hypotension
• Ototoxicity (all loop diuretics - can be temporary or permanent ringing
of ears, hearing loss or balance problems depending on the specific
medication)
• Hyperglycemia (especially in clients who have diabetes mellitus)
• Increased uric acid levels (hyperuricemia) with possible gouty arthritis in
susceptible clients
INTERVENTIONS • Monitor serum electrolyte levels periodically; notify provider for abnormal
levels
• Monitor carefully for signs of electrolyte imbalance
• If hypokalemia occurs, monitor for cardiac dysrhythmias
• If hypokalemia is a risk (e.g., client also taking digoxin) furosemide can be
combined with a potassium-sparing diuretic
• Monitor blood pressure frequently during treatment
• Ensure that the client does not take other ototoxic medications (additive
effect)
• Monitor for hearing loss, tinnitus, and vertigo
• Monitor blood glucose periodically in all clients
• Monitor blood glucose more frequently in clients who have diabetes
mellitus; insulin or oral antidiabetic medication dosage can need to be
increased
• Monitor uric acid levels periodically
ADMINISTRATION • Available for oral, IM, or IV use
• Give oral form with food to prevent GI manifestations
• If prescribed more than once daily, give second dose by early afternoon to
prevent nocturia and sleep loss
• Give IV form undiluted; administer slowly to prevent ototoxicity
• Protect all forms from light; store oral solution in refrigerator and other
forms at controlled room temperature
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