PATHOPHYSIOLOGY 370 MIDTERM
EXAM QUESTIONS WITH COMPLETE
SOLUTION.
A serious complication of deep vein thrombosis - (correct answer) -A pulmonary embolus
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Venous obstruction leads to edema because it ___________ pressure - (correct answer) -
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Increases capillary hydrostatic jl jl
A cause of thrombocytopenia includes - (correct answer) -chemotherapy
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Which is not a manifestation of acute arterial obstruction? - (correct answer) -Purpura
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Risk factors for atherosclerosis include - (correct answer) -Hyperlipidemia
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A laboratory test finding helpful in confirming the diagnosis of iron deficiency anemia is -
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(correct answer) -Elevated total iron-binding capacity
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The major cause of death from leukemic disease is - (correct answer) -Infection
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Pernicious anemia is caused by a lack of - (correct answer) -Intrinsic factor
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Activation of intrinsic pathway of coagulation is initiated by - (correct answer) -Tissue
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thromboplastin
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Tissues are able to auto-regulate their rate of blood flow by controlling - (correct answer) -
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Vascular resistance jl
A three-year-old boy who exhibits prolonged bleeding after minor trauma and a prolonged
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aPTT, but a normal platelet count, is likely to be diagnosed with - (correct answer) -
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Hemophilia
Blood flow throughout the periphery is regulated by - (correct answer) -The autonomic
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nervous system
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Patients with immunodeficiency disorders are usually first identified because they -
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(correct answer) -Develop recurrent infections
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, True or False: The anemia resulting from a deficiency of either vitamin B 12(cobalamin) or
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folate is caused by a disruption in DNA synthesis of the blast cells in the bone marrow that
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produces very large abnormal bone marrow cells called megaloblasts - (correct answer) -
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True
Which condition is associated with an elevated reticulocyte count? - (correct answer) -
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hemolytic anemia jl
What laboratory finding is usually found in aplastic anemia? - (correct answer) -
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Pancytopenia
Which disorder is considered a primary immunodeficiency disease? - (correct answer) -
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HIV/AIDS
A patient is diagnosed with a tortuous blood vessel of the right hand that bleeds
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spontaneously. This patient presents with - (correct answer) -Telangiectasia
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What characteristic is indicative of hemolytic anemia? - (correct answer) -Jaundice
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The movement of blood through the vascular system as opposed by the force of - (correct
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answer) -Resistance
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Autologous cell transplantation is a procedure in which - (correct answer) -Stem cells are
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harvested from the patient and then returned to the same patient
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Which causes vasoconstriction? - (correct answer) -Norepinephrine
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The hypersensitivity reaction that does not involve antibody production is type - (correct
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answer) -IV
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Disseminated intravascular coagulation may be treated with heparin therapy to - (correct jl jl jl jl jl jl jl jl jl jl jl
answer) -Inhibit clotting factor consumption
jl jl jl jl jl
The final step in clot formation is: - (correct answer) -Clot retraction
jl jl jl jl jl jl jl jl jl jl jl
Which condition enhances lymphatic flow? - (correct answer) -Increased interstitial fluid
jl jl jl jl jl jl jl jl jl jl
colloid osmotic pressure
jl jl jl
A low mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular
jl jl jl jl jl jl jl jl jl
volume (MCV) are characteristic of which type of anemia? - (correct answer) -Iron
jl jl jl jl jl jl jl jl jl jl jl jl jl
deficiency
jl
True or false: vaccination for pneumococcal pneumonia should be performed before one
jl jl jl jl jl jl jl jl jl jl jl
year of age in patients with sickle cell anemia - (correct answer) -False
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An increase in hemoglobin affinity for oxygen occurs with - (correct answer) -Shift to the left
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EXAM QUESTIONS WITH COMPLETE
SOLUTION.
A serious complication of deep vein thrombosis - (correct answer) -A pulmonary embolus
jl jl jl jl jl jl jl jl jl jl jl jl
Venous obstruction leads to edema because it ___________ pressure - (correct answer) -
jl jl jl jl jl jl jl jl jl jl jl jl
Increases capillary hydrostatic jl jl
A cause of thrombocytopenia includes - (correct answer) -chemotherapy
jl jl jl jl jl jl jl jl
Which is not a manifestation of acute arterial obstruction? - (correct answer) -Purpura
jl jl jl jl jl jl jl jl jl jl jl jl
Risk factors for atherosclerosis include - (correct answer) -Hyperlipidemia
jl jl jl jl jl jl jl jl
A laboratory test finding helpful in confirming the diagnosis of iron deficiency anemia is -
jl jl jl jl jl jl jl jl jl jl jl jl jl jl
(correct answer) -Elevated total iron-binding capacity
jl jl jl jl jl jl
The major cause of death from leukemic disease is - (correct answer) -Infection
jl jl jl jl jl jl jl jl jl jl jl jl
Pernicious anemia is caused by a lack of - (correct answer) -Intrinsic factor
jl jl jl jl jl jl jl jl jl jl jl jl
Activation of intrinsic pathway of coagulation is initiated by - (correct answer) -Tissue
jl jl jl jl jl jl jl jl jl jl jl jl
thromboplastin
jl
Tissues are able to auto-regulate their rate of blood flow by controlling - (correct answer) -
jl jl jl jl jl jl jl jl jl jl jl jl jl jl jl
Vascular resistance jl
A three-year-old boy who exhibits prolonged bleeding after minor trauma and a prolonged
jl jl jl jl jl jl jl jl jl jl jl jl
aPTT, but a normal platelet count, is likely to be diagnosed with - (correct answer) -
jl jl jl jl jl jl jl jl jl jl jl jl jl jl jl jl
Hemophilia
Blood flow throughout the periphery is regulated by - (correct answer) -The autonomic
jl jl jl jl jl jl jl jl jl jl jl jl
nervous system
jl jl
Patients with immunodeficiency disorders are usually first identified because they -
jl jl jl jl jl jl jl jl jl jl
(correct answer) -Develop recurrent infections
jl jl jl jl jl
, True or False: The anemia resulting from a deficiency of either vitamin B 12(cobalamin) or
jl jl jl jl jl jl jl jl jl jl jl jl jl jl
folate is caused by a disruption in DNA synthesis of the blast cells in the bone marrow that
jl jl jl jl jl jl jl jl jl jl jl jl jl jl jl jl jl jl
produces very large abnormal bone marrow cells called megaloblasts - (correct answer) -
jl jl jl jl jl jl jl jl jl jl jl jl jl
True
Which condition is associated with an elevated reticulocyte count? - (correct answer) -
jl jl jl jl jl jl jl jl jl jl jl jl
hemolytic anemia jl
What laboratory finding is usually found in aplastic anemia? - (correct answer) -
jl jl jl jl jl jl jl jl jl jl jl jl
Pancytopenia
Which disorder is considered a primary immunodeficiency disease? - (correct answer) -
jl jl jl jl jl jl jl jl jl jl jl
HIV/AIDS
A patient is diagnosed with a tortuous blood vessel of the right hand that bleeds
jl jl jl jl jl jl jl jl jl jl jl jl jl jl
spontaneously. This patient presents with - (correct answer) -Telangiectasia
jl jl jl jl jl jl jl jl jl
What characteristic is indicative of hemolytic anemia? - (correct answer) -Jaundice
jl jl jl jl jl jl jl jl jl jl
The movement of blood through the vascular system as opposed by the force of - (correct
jl jl jl jl jl jl jl jl jl jl jl jl jl jl jl
answer) -Resistance
jl jl
Autologous cell transplantation is a procedure in which - (correct answer) -Stem cells are
jl jl jl jl jl jl jl jl jl jl jl jl jl
harvested from the patient and then returned to the same patient
jl jl jl jl jl jl jl jl jl jl jl
Which causes vasoconstriction? - (correct answer) -Norepinephrine
jl jl jl jl jl jl
The hypersensitivity reaction that does not involve antibody production is type - (correct
jl jl jl jl jl jl jl jl jl jl jl jl
answer) -IV
jl jl
Disseminated intravascular coagulation may be treated with heparin therapy to - (correct jl jl jl jl jl jl jl jl jl jl jl
answer) -Inhibit clotting factor consumption
jl jl jl jl jl
The final step in clot formation is: - (correct answer) -Clot retraction
jl jl jl jl jl jl jl jl jl jl jl
Which condition enhances lymphatic flow? - (correct answer) -Increased interstitial fluid
jl jl jl jl jl jl jl jl jl jl
colloid osmotic pressure
jl jl jl
A low mean corpuscular hemoglobin concentration (MCHC) and mean corpuscular
jl jl jl jl jl jl jl jl jl
volume (MCV) are characteristic of which type of anemia? - (correct answer) -Iron
jl jl jl jl jl jl jl jl jl jl jl jl jl
deficiency
jl
True or false: vaccination for pneumococcal pneumonia should be performed before one
jl jl jl jl jl jl jl jl jl jl jl
year of age in patients with sickle cell anemia - (correct answer) -False
jl jl jl jl jl jl jl jl jl jl jl jl jl
An increase in hemoglobin affinity for oxygen occurs with - (correct answer) -Shift to the left
jl jl jl jl jl jl jl jl jl jl jl jl jl jl jl
