Pharmacology Final – SLCC UPDATED
ACTUAL Questions and CORRECT
Answers
Heartburn, Symptoms of GERD, Duodenal ulcers associated with H. Pylori, erosive esophagitis,
antimicrobial effect - CORRECT ANSWER - Indication for Omeprazole (Prilosec)
Action of Omeprazole (Prilosec) - CORRECT ANSWER - suppress gastric acid secretion
by specific inhibition of the H+/K+ ATPase enzyme system at the secretory surface of the gastric
parietal cell. Proton Pump Inhibitor
Gastric Duodenal ulcers, GERD, Hypersecretory conditions (Zollinger-Ellison syndrome),
Aspiration pneumonitis, Heartburn, Acid indigestion. - CORRECT ANSWER - Indication
for Ranitidine (Zantac)
Cautions related to magnesium sulfate and chronic renal failure - CORRECT ANSWER -
Kidneys cannot clear magnesium and it could cause hypermagnesmia. Could cause dehydration
and electrolyte loss from diarrhea.
ABX. Amoxicillin, clarithromycin, tetracycline, metronidazole. Gram-negative. PPI-H2 receptor
- antagonist bismuth. - CORRECT ANSWER - Treatment for H. Pylori
block the gastric H,K-ATPase, inhibiting gastric acid secretion. This effect enables healing of
peptic ulcers, gastroesophageal reflux disease (GERD), Barrett's esophagus, and Zollinger-
Ellison syndrome, as well as the eradication of H-pylori as part of combination regimens. -
CORRECT ANSWER - Action of Proton Pump Inhibitors
Replacement for digestive enzymes - CORRECT ANSWER - Pancrelipase/pancrease
IBS-C, chronic/severe constipation, GI perforation, ischemic colitis, Crohn's disease,
diverticulitis, megacolon, chronic or severe constipation - CORRECT ANSWER -
Contraindications for alostron (Lotrinex)
, Adverse effects of Metoclopramide (Reglan) - CORRECT ANSWER - CNS effects.
BLACK BOX WARNING: Severe depression.
Block H2 receptors, which reduces the volume of gastric acid and lowers the concentration of
hydrogen ions in the stomach. - CORRECT ANSWER - Action of H2 inhibitors
Action of Filgrastim (Neupogen) - CORRECT ANSWER - Increase neutrophils.
Stimulates production of Neutrophils.
Labs to monitor effectiveness of heparin - CORRECT ANSWER - PTT
inactivating thrombin and preventing the conversion of fibrinogen to fibrin. It also prevents the
formation of a stable fibrin clot in inhibiting the activation of the fibrin stabilizing factor. -
CORRECT ANSWER - Action of Heparin
Dependent on adequate quantities of iron, folic acid, vitamin B12. - CORRECT
ANSWER - Factor that promotes effectiveness of epoetin alfa
Action of alteplase (Activase) - CORRECT ANSWER - binds to the fibrin in a clot and
converts the plasminogen back to plasmin.
Antidote for Heparin - CORRECT ANSWER - Protamine
prevent clotting by activating antithrombin, indirectly inactivating both thrombin and factor Xa -
CORRECT ANSWER - Action of anticoagulant
bind to the fibrin in a clot and convert the plasminogen back to plasmin. Assist in the dissolving
of a clot. - CORRECT ANSWER - Action of thrombolytics
ACTUAL Questions and CORRECT
Answers
Heartburn, Symptoms of GERD, Duodenal ulcers associated with H. Pylori, erosive esophagitis,
antimicrobial effect - CORRECT ANSWER - Indication for Omeprazole (Prilosec)
Action of Omeprazole (Prilosec) - CORRECT ANSWER - suppress gastric acid secretion
by specific inhibition of the H+/K+ ATPase enzyme system at the secretory surface of the gastric
parietal cell. Proton Pump Inhibitor
Gastric Duodenal ulcers, GERD, Hypersecretory conditions (Zollinger-Ellison syndrome),
Aspiration pneumonitis, Heartburn, Acid indigestion. - CORRECT ANSWER - Indication
for Ranitidine (Zantac)
Cautions related to magnesium sulfate and chronic renal failure - CORRECT ANSWER -
Kidneys cannot clear magnesium and it could cause hypermagnesmia. Could cause dehydration
and electrolyte loss from diarrhea.
ABX. Amoxicillin, clarithromycin, tetracycline, metronidazole. Gram-negative. PPI-H2 receptor
- antagonist bismuth. - CORRECT ANSWER - Treatment for H. Pylori
block the gastric H,K-ATPase, inhibiting gastric acid secretion. This effect enables healing of
peptic ulcers, gastroesophageal reflux disease (GERD), Barrett's esophagus, and Zollinger-
Ellison syndrome, as well as the eradication of H-pylori as part of combination regimens. -
CORRECT ANSWER - Action of Proton Pump Inhibitors
Replacement for digestive enzymes - CORRECT ANSWER - Pancrelipase/pancrease
IBS-C, chronic/severe constipation, GI perforation, ischemic colitis, Crohn's disease,
diverticulitis, megacolon, chronic or severe constipation - CORRECT ANSWER -
Contraindications for alostron (Lotrinex)
, Adverse effects of Metoclopramide (Reglan) - CORRECT ANSWER - CNS effects.
BLACK BOX WARNING: Severe depression.
Block H2 receptors, which reduces the volume of gastric acid and lowers the concentration of
hydrogen ions in the stomach. - CORRECT ANSWER - Action of H2 inhibitors
Action of Filgrastim (Neupogen) - CORRECT ANSWER - Increase neutrophils.
Stimulates production of Neutrophils.
Labs to monitor effectiveness of heparin - CORRECT ANSWER - PTT
inactivating thrombin and preventing the conversion of fibrinogen to fibrin. It also prevents the
formation of a stable fibrin clot in inhibiting the activation of the fibrin stabilizing factor. -
CORRECT ANSWER - Action of Heparin
Dependent on adequate quantities of iron, folic acid, vitamin B12. - CORRECT
ANSWER - Factor that promotes effectiveness of epoetin alfa
Action of alteplase (Activase) - CORRECT ANSWER - binds to the fibrin in a clot and
converts the plasminogen back to plasmin.
Antidote for Heparin - CORRECT ANSWER - Protamine
prevent clotting by activating antithrombin, indirectly inactivating both thrombin and factor Xa -
CORRECT ANSWER - Action of anticoagulant
bind to the fibrin in a clot and convert the plasminogen back to plasmin. Assist in the dissolving
of a clot. - CORRECT ANSWER - Action of thrombolytics
