Infarction Questions with Verified Answers
Effect of venous and arteriolar dilation on oxygen demand during angina
Ans✔✔-- NTG dilates arterioles (reduces systemic BP and thus
resistance) - decreased afterload
- NTG dilates (coronary) veins (reduces venous pressure) - decreased
venous return - decreased preload
*reduced preload and afterload result in reduced demands of the cardiac
muscle
Effect of venous and arteriolar dilation on oxygen supply during angina
Ans✔✔-- NTG dilates healthy coronary arteries. Collateral artery dilation
can increase the blood flow to the ischemic area - increases coronary
blood flow
Coronary artery disease (CAD, coronary heart disease, ischemic heart
disease) Ans✔✔-- heart disease due to impaired delivery of blood to the
myocardium
- the result of atherosclerosis of coronary arteries
Conditions that decrease coronary blood flow other than atherosclerosis
Ans✔✔-- poor perfusion (e.g., hypovolemia, hypotension, aortic stenosis,
dysrhythmias)
- coronary vasospasm (e.g., cocaine overdose)
, - coronary embolism (e.g., due to endocarditis)
Classifying CAD based on the extent of occlusion Ans✔✔-- partial
- complete
Classifying CAD on the speed of ischemic development Ans✔✔-- acute
- chronic
Presentations of CAD Ans✔✔-- asymptomatic
- angina pectoris
- congestive heart failure
-myocardial infarct
Plaque Ans✔✔-- 10-25% occlusion
- results: asymptomatic or angina pectoris
Nonocclusive thrombus Ans✔✔-- transient thrombus but leads to angina
pectoris
or
- recurrent ischemic episodes but leads to congestive heart failure
*partial occlusion that is chronic