PATHOPHYSIOLOGY
THE BIOLOGIC BASIS FOR DISEASE IN ADULTS AND CHILDREN
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8th Edition
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Kathryn L. McCance, Sue E. Huether
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Contents
Chapterb01:bCellularbBiology .......................................................................................................................... 4
Chapterb02:bAlteredbCellularbandbTissuebBiology:bEnvironmentalbAgents .................................................... 18
Chapterb03:bThebCellularbEnvironment:bFluidsbandbElectrolytes,bAcidsbandbBases ....................................... 31
Chapterb04:bGenesbandbGeneticbDiseases .................................................................................................... 44
Chapterb05:bGenes,bEnvironment-Lifestyle,bandbCommonbDiseases ............................................................ 55
Chapterb06:bEpigeneticsbandbDisease ........................................................................................................... 63
Chapterb07:bInnatebImmunity:bInflammationbandbWoundbHealing .............................................................. 68
Chapterb08:bAdaptivebImmunity .................................................................................................................. 83
Chapterb09:bAlterationsbinbImmunitybandbInflammation.............................................................................. 95
Chapterb10:bInfection................................................................................................................................. 108
Chapterb11:bStressbandbDisease ................................................................................................................. 117
Chapterb12:bCancerbBiology ....................................................................................................................... 124
Chapterb13:bCancerbEpidemiology ............................................................................................................. 137
Chapterb14:bCancerbinbChildren.................................................................................................................. 143
Chapterb15:bStructurebandbFunctionbofbthebNeurologicbSystem ................................................................. 148
Chapterb16:bPain,bTemperaturebRegulation,bSleep,bandbSensorybFunction ................................................ 159
Chapterb17:bAlterationsbinbCognitivebSystems,bCerebralbHemodynamics,bandbMotorbFunction ................ 174
Chapterb18:bDisordersbofbthebCentralbandbPeripheralbNervousbSystemsbandbthebNeuromuscularbJunction
.................................................................................................................................................................. 188
Chapterb19:bNeurobiologybofbSchizophrenia,bMoodbDisorders,bandbAnxietybDisorders ............................. 199
Chapterb20:bAlterationsbofbNeurologicbFunctionbinbChildren ...................................................................... 206
Chapterb21:bMechanismsbofbHormonalbRegulation.................................................................................... 213
Chapterb22:bAlterationsbofbHormonalbRegulation ...................................................................................... 222
Chapterb23:bObesitybandbDisordersbofbNutrition ........................................................................................ 234
Chapterb24:bStructurebandbFunctionbofbthebReproductivebSystems ........................................................... 239
Chapterb25:bAlterationsbofbthebFemalebReproductivebSystem ................................................................... 249
Chapterb26:bAlterationsbofbthebMalebReproductivebSystem ....................................................................... 259
Chapterb27:bSexuallybTransmittedbInfections ............................................................................................. 265
Chapterb28:bStructurebandbFunctionbofbthebHematologicbSystem .............................................................. 273
Chapterb29:bAlterationsbofbErythrocytes,bPlatelets,bandbHemostaticbFunction .......................................... 283
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Chapterb30:bAlterationsbofbLeukocytebandbLymphoidbFunction ................................................................. 293
Chapterb31:bAlterationsbofbHematologicbFunctionbinbChildren ................................................................... 300
Chapterb32:bStructurebandbFunctionbofbthebCardiovascularbandbLymphaticbSystems ................................. 311
Chapterb33:bAlterationsbofbCardiovascularbFunction .................................................................................. 324
Chapterb34:bAlterationsbofbCardiovascularbFunctionbinbChildren ................................................................ 338
Chapterb35:bStructurebandbFunctionbofbthebPulmonarybSystem ................................................................. 346
Chapterb36:bAlterationsbofbPulmonarybFunction ........................................................................................ 356
Chapterb37:bAlterationsbofbPulmonarybFunctionbinbChildren ...................................................................... 373
Chapterb38:bStructurebandbFunctionbofbthebRenalbandbUrologicbSystems................................................... 381
Chapterb39:bAlterationsbofbRenalbandbUrinarybTractbFunction ................................................................... 391
Chapterb40:bAlterationsbofbRenalbandbUrinarybTractbFunctionbinbChildren ................................................. 401
Chapterb41:bStructurebandbFunctionbofbthebDigestivebSystem .................................................................... 409
Chapterb42:bAlterationsbofbDigestivebFunction........................................................................................... 421
Chapterb43:bAlterationsbofbDigestivebFunctionbinbChildren ........................................................................ 432
Chapterb44:bStructurebandbFunctionbofbthebMusculoskeletalbSystem ........................................................ 441
Chapterb45:bAlterationsbofbMusculoskeletalbFunction ............................................................................... 453
Chapterb46:bAlterationsbofbMusculoskeletalbFunctionbinbChildren ............................................................. 466
Chapterb47:bStructure,bFunction,bandbDisordersbofbthebIntegument .......................................................... 475
Chapterb48:bAlterationsbofbthebIntegumentbinbChildren ............................................................................. 486
Chapterb49:bShock,bMultiplebOrganbDysfunctionbSyndrome,bandbBurnsbinbAdults ..................................... 494
Chapterb50:bShock,bMultiplebOrganbDysfunctionbSyndrome,bandbBurnsbinbChildren .................................. 502
, TestbBankb-bPathophysiology:bThebBiologicbBasisbforbDiseasebinbAdultsbandbChildrenb(8th)b b 4
Chapter 01: Cellular Biology
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MULTIPLEbCHOICE
1. Whichbstatementbbestbdescribesbthebcellularbfunctionbofbmetabolicbabsorption?
a. Cellsbcanbproducebproteins.
b. Cellsbcanbsecretebdigestivebenzymes.
c. Cellsbcanbtakebinbandbusebnutrients.
d. Cellsbcanbsynthesizebfats.
ANS:b C
Inbmetabolicbabsorption,ballbcellsbtakebinbandbusebnutrientsbandbotherbsubstancesbfrombtheirbsurrounding
s.bThebremainingboptionsbarebnotbinclusivebinbtheirbdescriptionsbofbcellularbmetabolicbabsorption.
PTS:b b 1 DIF: CognitivebLevel:bRemembering
2. Wherebisbmostbofbabcell’sbgeneticbinformation,bincludingbRNAbandbDNA,bcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS:b C
Thebnucleusbcontainsbthebnucleolus,babsmallbdensebstructurebcomposedblargelybofbRNA,bmostbofbth
ebcellularbDNA,bandbthebDNA-
bindingbproteins,bsuchbasbthebhistones,bwhichbregulatebitsbactivity.bThebmitochondriabarebresponsi
blebforbcellularbrespirationbandbenergybproduction.
Ribosomes’bchiefbfunctionbisbtobprovidebsitesbforbcellularbproteinbsynthesis.bLysosomesbfunctionba
sbthebintracellularbdigestivebsystem.
PTS:b b 1 DIF: CognitivebLevel:bRemembering
3. Whichbcomponentbofbthebcellbproducesbhydrogenbperoxideb(H2O2)bbybusingboxygenbtobremovebh
ydrogenbatomsbfrombspecificbsubstratesbinbanboxidativebreaction?
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS:b B