Pharm Exam #2: A Tale of Triumph and Ferocity

Pharm Exam #2: A Tale of Triumph and Ferocity
Study online at https://quizlet.com/_fsuqna

1. Angiotensin-convert- captopril (Capoten)
ing enzyme (ACE)
inhibitor

2. captopril (Capoten) Block enzyme that converts angiotensin I
EPA to angiotensin II. This decreases vasoconstriction and
aldosterone release (fluid volume and K+ increase).

3. captopril (Capoten) PO
Admin

4. captopril (Capoten) Treat hypertension and heart failure
TU

5. captopril (Capoten) - ortho hypo
ADRs - dry and nonproductive cough
- hyperkalemia
- angioedema
- taste distortions
- rash

6. captopril (Capoten) - teratogenic
C/I - breastfeeding
- liver disease
- NSAIDS

7. captopril (Capoten) - avoid salts
I/E - monitor BP before, during, and after
- educate about cough
- monitor K+ since drug increases K+ retention
(Potassium should stay between 3.5 and 5.0 mEq/L)

8. Angiotensin II Re- losartan (Cozaar)
ceptor Blocker
(ARBs)

9. losartan (Cozaar) Blocks vasoconstriction and aldosterone from being
EPA stimulated. Results in vasodilation and K+ retention.

10. PO
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, Pharm Exam #2: A Tale of Triumph and Ferocity
Study online at https://quizlet.com/_fsuqna
losartan (Cozaar)
Admin

11. losartan (Cozaar) TU - Treat HTN
- Stroke prevention
- Diabetic Nephropathy

12. losartan (Cozaar) - angioedema
ADRs - dizziness
- hypotension
- HA
- insomnia

13. losartan (Cozaar) C/I - teratogenic
- breastfeeding
- children under 6
- NSAIDS
- lithium

14. losartan (Cozaar) I/E - monitor BP before, during, and after
- monitor K+ (less risk than ACE)
- monitor for angioedema (skin wheals, tongue
swelling)

15. Aldosterone Antago- eplerenone (Inspra)
nist

16. eplerenone (Inspra) Blocks aldosterone receptors. Results in less NA and
EPA water, more K+ retention.

17. eplerenone (Inspra) PO, takes up to 4 weeks
Admin

18. eplerenone (Inspra) For hypertension and symptoms of heart failure after
TU MI

19. eplerenone (Inspra) Hyperkalemia, very common
ADRs

20.
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