COMSAE #1 Questions and Answers 100% Pass
Balantium Coli
reservoir/diagnosis/histology/symptoms/treatment/mechanism - ANSWER ✔✔-r:
PIGS
dx:
CYSTS in poop ("looks like a perfect circle")
Histo:
BEAN SHAPED MACROnucleus
Sx:
watery/dysenteric stool
persistant diarrhea
abd. pain
colon perforation -> sepsis
Created by Grace Amelia © 2025, All Rights Reserved.
,2|Page
mech:
invades colon wall -> possible bloody stool
Tx:
Tetracycline
Metro
Iodoquinol
Wucheria bancrofti
sx/dx/tx - ANSWER ✔✔-sx:
lymphedema (elephantiasis, hydrocele of scrotum, pulmonary eosinophilia syndrome)
dx:
blood smear (giemsa stain/ H&E)
tx:
Diethylcarbamazine (sensitizes bug to phagocytosis)
Tx for pseudomonas - ANSWER ✔✔-piper/tazo (penicillin w/b-lactam inhibitor)
Isoniazid:
causes 1 in G6PD pts
Created by Grace Amelia © 2025, All Rights Reserved.
, 3|Page
inhibits 2
AE = 3 & 4 & 5
moa? - ANSWER ✔✔-1. hemolysis
2. P-450
3. hepatitis & 4. neuropathy (B6 def.)
5. Drug-induced lupus
MOA:
dec. synthesis of mycolic acids & NEEDS KATG gene
Lennox-Gastaut Syndrome
epi/sx/eeg - ANSWER ✔✔-epi:
2-8 yo
sx:
mental retardation & seizures
EEG:
slow spikes & wave pattern
Created by Grace Amelia © 2025, All Rights Reserved.