Basic and clinical pharmacology 15th edition katzung trevor test ban

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BASIC AND CLINICAL PHARMACOLOGY 15TH EDITION
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KATZUNG TREVOR TEST BANK
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INCLUSIVEmOFmCHAPTERSm1-
66mCOMPLETEmWITHmEXPLAINEDmANSWERS

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Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test Bank
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Chapterm1.mIntroduction:mThemNaturemofmDrugsm&mDrugmDevelopmentm&mRegulation


1.
Amnursemworkingminmradiologymadministersmiodinemtomampatientmwhomismhavi
ngmamcomputedmtomographym(CT)mscan.mThemnursemworkingmonmthemoncology
munitmadministersmchemotherapymtompatientsmwhomhavemcancer.mAtmthemPublicm

HealthmDepartment,mamnursemadministersmammeasles-mumps-
rubellam(MMR)mvaccinemtomam14-month-
oldmchildmasmamroutinemimmunization.mWhichmbranchmofmpharmacologymbestmd
escribesmthemactionsmofmallmthreem nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:

Pharmacologymismthemstudymofmthembiologicmeffectsmofmchemicals.mNursesmarem
involvedmwithmclinicalmpharmacologymormpharmacotherapeutics,mwhichmismamb
ranchmofmpharmacologymthatmdealsmwithmthemusesmofmdrugsmtomtreat,mprevent,ma
ndmdiagnosemdisease.mThemradiologymnursemismadministeringmamdrugmtomhelpmd
iagnosemamdisease.mThemoncologymnursemismadministeringmamdrugmtomhelpmtreat
mamdisease.mPharmacoeconomicsmincludesmanymcostsminvolvedminmdrugmtherapy.
Pharmacodynamicsminvolvesmhowmamdrugmaffectsmthembodymandmpharmacokine
ticsmismhowmthembodymactsmonmthembody.



2.
WhenminvolvedminmphasemIIImdrugmevaluationmstudies,m
whatmresponsibilitiesmwouldmthemnursemhave?
A) Workingmwithmanimalsmwhomaremgivenmexperimentalm drugs
B) Choosingmappropriatempatientsmtombeminvolvedminmthemdrugm study
C) Monitoringmandmobservingmpatientsmcloselymformadversem effects
D) Conductingmresearchmtomdeterminemeffectivenessmofmthem drug

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Ans: C
Feedback:

PhasemIIImstudiesminvolvemusemofmamdrugminmamvastmclinicalmpopulationminmwh
ichmpatientsmaremaskedmtomrecordmanymsymptomsmtheymexperiencemwhilemtaki
ngmthemdrugs.mNursesmmaymbemresponsiblemformhelpingmcollectmandmanalyzemt
heminformationmtombemsharedmwithmthemFoodmandmDrugmAdministrationm(FD
A)mbutmwouldmnotmconductmresearchmindependentlymbecausemnursesmdomnotmp
rescribemmedications.mUsemofmanimalsminmdrugmtestingmismdoneminmthemprecli
nicalmtrials.mSelectmpatientsmwhomareminvolvedminmphasemIImstudiesmtompartici
pateminmstudiesmwheremthemparticipantsmhavemthemdiseasemthemdrugmismintende
dmtomtreat.mThesempatientsmaremmonitoredmcloselymformdrugmactionmandmadver
semeffects.mPhasemImstudiesminvolvemhealthymhumanmvolunteersmwhomaremusu
allympaidmformtheirmparticipation.mNursesmmaymobservemformadversemeffectsma
ndmtoxicity.




3.
Amphysicianmhasmorderedmintramuscularm(IM)minjectionsmofmmorphine,mamna
rcotic,meverym4mhoursmasmneededmformpainminmammotormvehiclemaccidentmvictim.
mThemnursemismawaremthismdrugmhasmamhighmabusempotential.mUndermwhatmcate

gorymwouldmmorphinembemclassified?
A) SchedulemI
B) SchedulemII
C) SchedulemIII
D) SchedulemIV
Ans: B
Feedback:

NarcoticsmwithmamhighmabusempotentialmaremclassifiedmasmSchedulemIImdrugsm
becausemofmseveremdependencemliability.mSchedulemImdrugsmhavemhighmabuse
mpotentialmandmnomacceptedmmedicalmuse.mSchedulemIIImdrugsmhavemamlesserm


abusempotentialmthanmIImandmanmacceptedmmedicalmuse.mSchedulemIVmdrugsmha
vemlowmabusempotentialmandmlimitedmdependencem liability.

4.
Whatmconceptmismconsideredmwhenmgenericmdrugsmaremsubstitutedmformb
randmnamemdrugs?
A) Bioavailability

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