TestnBanknAdvancednPhysiologynandnPathophysiologynEssentialsnforn ClinicalnPracticen1stnEditionnTkac 1
s
Advanced Physiology and Pathophysiology Essentials for
n n n n n n
Clinical Practice 1st Edition Tkacs
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Chapter 1. THE FOUNDATIONAL CONCEPTS OF CLINICALPRACTICE
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1. Thencharacteristic,n localizedn cardinalnsignsn ofnacuteninflammationn include:
A) fever.
B) fatigue.
C) redness.
D) granuloma.
2.
Then vascular,n hemodynamicn stagen ofnacuteninflammationnisn initiatedn bynmo
mentaryn vasoconstrictionn followedn bynvasodilationn thatn causesn localized:
A) bleeding.
B) congestion.
C) palenskin.
D) coolness.
3.
Thencellularn stagen ofnacuten inflammationn isnmarkednbynthenmovementn ofnle
ukocytesn intonthenarea.nWhichn ofnthen followingn cellsnarrivesnearlyn inn greatnnu
mbers?
A) Basophils
B) Lymphocytes
C) Neutrophils
D) Platelets
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4.
Thenphagocytosisn processninvolvesn threen distinctn steps.n Whatn isn then initi
alnstepninnthenprocess?
A) Engulfment
B) Intracellularn killing
C) Antigennmargination
D) Recognitionnandn adherence
5.
Whichnofnthen followingn mediatorsn ofninflammationncausesn increasedn capillar
ynpermeabilitynandnpain?
A) Serotonin
B) Histamine
C) Bradykinin
D) Nitricnoxide
6.
Inflammatorynexudatesn aren an combinationn ofnseveraln types.n Whichn ofnth
enfollowingnexudatesn isncomposedn ofnenmeshedn necroticncells?
A) Serous
B) Fibrinous
C) Suppurative
D) Membranous
7. Then acute-
phasen systemicn responsen usuallynbeginsn withinn hoursn ofnthen onsetnofninflamm
ationnandnincludes:
A) fevernandn lethargy.
B) decreasedn C-reactiven protein.
C) positiven nitrogenn balance.
D) lownerythrocyten sedimentationn rate.
8.
Inncontrastn tonacuten inflammation,nchronicn inflammationnisn characterizednb
ynwhichnofnthen followingnphenomena?
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A) Profusenfibrinousnexudation
B) Anshiftntonthenleftn ofngranulocytes
C) Metabolicn andn respiratorynalkalosis
D) Lymphocytosisn andn activatedn macrophages
9. Exogenousn pyrogensn (interleukin-
1)n andnthen presencen ofnbacterian innthen bloodnleadntonthenreleasen ofnendogenousnp
yrogensn that:
A) stabilizenthermalncontroln innthen brain.
B) producen leukocytosisn andn anorexia.
C) blockn viraln replicationninncells.
D) inhibitn prostaglandinnrelease.
10 Annoldern adultn patientn hasnjustn shearedn thenskinn onnhernelbown whilen attempted
.
tonboostn herselfnupn innbed,nanneventnthatn hasnprecipitatedn acuten inflammatio
nninnthen regionnsurroundingnthenwound.n Whichn ofnthen followingneventsn willnoc
curn duringnthen vascularnstagen ofnthenpatientsninflammation?
A) Outpouringnofnexudaten inton interstitialnspaces
B) Chemotaxis
C) Accumulationnofn leukocytesn alongn thenepithelium
D) Phagocytosisn ofncellularndebris
11 Whichnofnthen followingn individualsnmostn likelynhasn then highestn riskn of
. experiencingn chronicn inflammation?
A) Anpatientn whon hasn recentlynbeenn diagnosedn withntypen 2n diabetes
B) Anpatientnwhon isnancarriernofnannantibiotic-resistantn organism
C) Anpatientnwhon isn takingn oralnantibioticsn forn annuppernrespiratoryninfection
D) Anpatientnwhonisn morbidlynobesen andn whon hasn an sedentarynlifestyle
12 Whichn ofnthen following core body temperatures is within normal range?
.
A) 35.9Cn (96.6F)
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B) 38.0Cn (100.4F)
C) 35.5Cn (95.9F)
D) 37.3Cn (99.1F)
13 Anpostsurgicaln patientn whonisn recoveringn innthen postanestheticn recoverynunit
.
statesnthatn shen isn freezingncold.n Whichn ofnthen followingn measuresn isn likelynt
onbeninitiatedn innthenpatientsn hypothalamusn innanneffortn tonreducenheatn loss?
A) Openingn ofnarteriovenousn(AV)n shunts
B) Reducednexhalationn ofnwarmednair
C) Contractionn ofnpilomotorn muscles
D) Decreasedn urinen production
14 Annelderlynpatientn isndressedn onlyninnan hospitalngownn andncomplainsn ofna
.
draftn innhernroom.n Consequently,n shen hasn requestednan warmnblanketn whilen sh
ensitsn innhernwheelchair.n Whichnofnthenfollowingnmechanismsn ofnheatnlossnisnmo
stn likelynthenprimaryncausen ofnhernrequest?
A) Evaporationn andn conduction
B) Radiationnandn convection
C) Conductionn andn convection
D) Convectionnandn evaporation
15 Whichn ofnthen followingnpathophysiologicn processesn aren capablen ofn inducing
. then productionn ofnpyrogens?n Selectn allnthatnapply.
A) Acuteninflammation
B) Obesity
C) Myocardialninfarction
D) Malignancy
E) Renalnfailure
16 Whichn ofnthen followingnpatientsn isn mostn likelyntonben susceptiblen to
. developingnan neurogenicn fever?